Cycled while taking multiple mood stabilizers and an atypical antidepressant. Started at 200mg Test E/wk then eased into 400mg Test E/wk for 12 weeks as a trial run - I really should have started lower than 200, but I was eager, which is a poor excuse. However, I was fine the whole time. I had several multi-compound cycles under my belt from about 5 or 6 years prior, so I also knew what I was getting into.
I messed around with Tren in the past, but I should not have done that - undiagnosed bipolar 1 at the time. It messed with everything in my life. Like everything. I am in a much better place now, oddly enough because of the sequence of events that followed the Trentastrophe on my life. When you take Tren, you feel like god. Then you get off it and you think, "Holy fuck, that messed me up. I will never touch it again." After a while, that line of thought changes to, "Welllllll, maybe a baby dose of 75-100mg/wk won't kill me." I'm battling those thoughts right now. Lol. God save the world around me if I fuck with Tren again. Point is, Tren isn't right for everyone, but it's especially not right for those with mental health disorders. Just avoid it.
Anyway, I agree with the other advice. Dial in your diet, training, sleep, meds, mood, have a rock solid (and very well-researched) plan before you start, and create an emergency plan with a person or people you trust to inform about this. Until you have those seven things locked down, don't start. When you do start, ease into it and continually assess.
If you're wondering about physical interactions between compounds, I have not found anything significant in the substances I have used or researched.
The best advice is to talk to a doc, but we know how that may go, which is likely why you're her. My advice is based on my experience - yours may wildly vary. Proceed with great caution.