Dutasteride frontload

[maybechris]

if you crash your dht like this youre gonna be so much more likely to develop gyno/mood disorder as pickle rick said. just wait lol
front loading dut lmaoooo

I got the message, i'm not frontloading. I don't really see much of a correlation between dut and gyno tho?

 

[docpepper]

Dut starts working quickly even if you don’t saturate serum levels immediately. It’s weird like that, there is a good Haircafe video on it somewhere that explains why.

Seems like a waste to front load, if you’re paranoid and wanna be fully covered just take fin for a few weeks along with your dut until you’re at steady state. When I switched I didn’t even bother and didn’t notice any shedding but then my AGA is very minor.

 

[Sera]

I got the message, i'm not frontloading. I don't really see much of a correlation between dut and gyno tho?

DHT prevents estrogen from causing breast growth.

 

[deuces_00]

I got the message, i'm not frontloading. I don't really see much of a correlation between dut and gyno tho?

youre more likely to experience estrogen sides when your estrogen to dht ratio is off. if you crash DHT, then gyno/other estrogen sides are much more likely to occur.
Same is true for the inverse - if your estrogen is crashed youre more likely to have DHT sides (hairloss, prostate issues xyz).

This is my understanding and would love to be corrected by a vet if wrong!

 

[BigDadd7]

I got the message, i'm not frontloading. I don't really see much of a correlation between dut and gyno tho?

Estrogen binds to receptors in male breast tissue → activates growth.

Normally, DHT competes with this effect by binding to androgen receptors that suppress estrogenic stimulation.

Low DHT = unchecked estrogen action → tissue growth and tenderness.

 

[maybechris]

DHT prevents estrogen from causing breast growth.

Estrogen binds to receptors in male breast tissue → activates growth.

Normally, DHT competes with this effect by binding to androgen receptors that suppress estrogenic stimulation.

Low DHT = unchecked estrogen action → tissue growth and tenderness.

youre more likely to experience estrogen sides when your estrogen to dht ratio is off. if you crash DHT, then gyno/other estrogen sides are much more likely to occur.
Same is true for the inverse - if your estrogen is crashed youre more likely to have DHT sides (hairloss, prostate issues xyz).

This is my understanding and would love to be corrected by a vet if wrong!

Ok, i wasn't aware of that, my estrogen is quite low right now anyways, so don't need to worry about it yet.. Does this really have a significant Impact tho, tons of people have been on dutasteride for ages and didn't get gyno.

 

[demon]

Because it doesn’t have any benefits. Hair loss, loss of elastin, upregulation of sebaceous glands (meaning acne). It’s not anabolic (metabolised by 3-alpha-hydroxysteroid reductase in muscle tissue (non-androgenic tissue)). There isn’t a good reason to have it circulating your body at all.

Been on 2.5mg Dut for over a year. No issues at all. No regrets being on. I knew sides were an meme by r/tressless schizos so I didn’t bother with 0.5mg. 2.5mg vs 0.5mg serum levels are practically the same anyway (nuked), just scalp DHT there’s an extra 30% suppression.

.5 mg for 3 years for me and no sides to speak of. I take it mainly for prostrate protection, but my full head of hair is an added benefit.