Here's a chronology of my trials with E control.
Current TRT regimen: Depo-Test - 80mg/week, Avodart - 0.5mg ED, Arimidex - 0.25mg, 3x/week.
5/04........Total E = 187 (Quest Norm, <130)
6/04.........Began I3C, 400mg. ED (Life Ext. brand)
9/04.........Tot. E = 100
12/04.......DC'd Arimidex (Perhaps no longer necessary.)
2/05.........Tot. E = 101. (But, estrone, previously low-norm,
goes high.)
3/05.........Resumed Adex @ 0.25mg 3x/week
Life Ext. reformulates their I3C. Supposedly better. I remain
@400mg.
5/05........Tot. E = 171
7/05........Tot. E = 186
8/05........Raised I3C to 600mgs ED
10/05.....Tot. E = 127
12/05..... Switched to DIM 120mg @ Doc's suggestion.
2/06.......Tot. E = 125.
DIM supplement is EnzymaticTherapy's EstroBalance.
My doctor feels that I3C may increase the 4-OH estrogen fractions so, recommends DIM.