TrenGoblin
New Member
Hi,
its my first post im usually just reading, so idk if its the right forum to post this sry, please move this if i am wrong.
I know there are a lot of discussions about follistatin/myostatin inhibition without any results, but a few months ago i came across this on ergo-log from a thread at PM:
FST-DHBS-MFC ( there is also one called FST-DHBS-fc, i think they are similar?)
Its a follistatin molecule which caused and increase of 19% muscle size within ~a week.
I mean even if its 19% within a month it a huge amount of muscle those mice where adding in a short time period.
I did a bit of research and found the protein sequence of FST-DHBS-FC from here. I think they are really similar?
FST-DHBS-FC (542aa)
-----------------------------------------------------------------------------------------------------------------
GNCWLRQAKNGRCQVLYKTELSKEECCSTG
RLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCG
PGQSCVVDQTGSPRCVCAPDCSNITWKGPVCGLDGKTYRNECA
LLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNA
YCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSI
GLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELC
PDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN
SISEDTEEEEEDEDQDYSFPISSILEWVPRDCGCKPCICTVPEVS
SVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVE
VHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNS
AAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMI
TDFFPEDITVEWQWNGQPAENYKNTQPIMDTDGSYFVYSKLN
VQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK
-----------------------------------------------------------------------------------------------------------------
I was researching but couldnt find a company which offered protein sequencing (i think that what its called) for an protein this long.
The only other method i found is something called recombinant-DNA synthesis. but its insanely expensive.
My question is:
Does anybody know how proteins of this length can be manufactured at a reasonable price? There has to be a way.
Most companies even legit ones are only offering aa sequencing for aa with a length up to maybe 100-200 aa.
its my first post im usually just reading, so idk if its the right forum to post this sry, please move this if i am wrong.
I know there are a lot of discussions about follistatin/myostatin inhibition without any results, but a few months ago i came across this on ergo-log from a thread at PM:
FST-DHBS-MFC ( there is also one called FST-DHBS-fc, i think they are similar?)
Its a follistatin molecule which caused and increase of 19% muscle size within ~a week.
I mean even if its 19% within a month it a huge amount of muscle those mice where adding in a short time period.
I did a bit of research and found the protein sequence of FST-DHBS-FC from here. I think they are really similar?
FST-DHBS-FC (542aa)
-----------------------------------------------------------------------------------------------------------------
GNCWLRQAKNGRCQVLYKTELSKEECCSTG
RLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCG
PGQSCVVDQTGSPRCVCAPDCSNITWKGPVCGLDGKTYRNECA
LLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNA
YCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSI
GLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELC
PDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCN
SISEDTEEEEEDEDQDYSFPISSILEWVPRDCGCKPCICTVPEVS
SVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVE
VHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNS
AAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMI
TDFFPEDITVEWQWNGQPAENYKNTQPIMDTDGSYFVYSKLN
VQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK
-----------------------------------------------------------------------------------------------------------------
I was researching but couldnt find a company which offered protein sequencing (i think that what its called) for an protein this long.
The only other method i found is something called recombinant-DNA synthesis. but its insanely expensive.
My question is:
Does anybody know how proteins of this length can be manufactured at a reasonable price? There has to be a way.
Most companies even legit ones are only offering aa sequencing for aa with a length up to maybe 100-200 aa.