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[Ghoul]

I've gotten several orders from Marcus, all well packaged, and only one delayed shipping issue. My only question is, has anyone else used the tirzepatide with any success? My wife went through 4 vials with little results. Keep in mind, she did not change her eating habits much and did very little exercise to help the process, but still. She only lost a total of 6 pounds from 4 vials.

What was her dosing protocol?

Has she used other GLPs before?

 

[Mayne]

Yo sir Marcus @GenericAsia when promotion

 

[PanamaVet]

What was her dosing protocol?

Has she used other GLPs before?

Started her with the standard 2.5mg/week for a month and then titrated her up to 5mg/week. She has never used any other GLPs.

 

[Ghoul]

Started her with the standard 2.5mg/week for a month and then titrated her up to 5mg/week. She has never used any other GLPs.

It's not uncommon with Tirz to not see a significant response until getting to 7.5 or 10. Try not to leave a long gap, and keep it going, or it could impair her response going forward.

When it kicks in, she won't have to put effort into not eating, just choosing the correct, protein dense, foods.

 

[PanamaVet]

It's not uncommon with Tirz to not see a significant response until getting to 7.5 or 10. Try not to leave a long gap, and keep it going, or it could impair her response going forward.

When it kicks in, she won't have to put effort into not eating, just choosing the correct, protein dense, foods.

Thanks, I appreciate your response. We'll give it a try again. She's not taken any for a month now, start back at 5 or go straight to 7.5/10?

 

[Ghoul]

Thanks, I appreciate your response. We'll give it a try again. She's not taken any for a month now, start back at 5 or go straight to 7.5/10?

I'd start her on one week of 5mg. Then 7.5 for 4. Keep in mind it takes four weekly doses to reach maximum blood plasma concentration at a given dose. So effects will increase at the same dose from first to fourth dose. Then 10, 12.5 each for 4 weeks. to 15 if she's tolerating it ok and not at goal weight. She can stay at any given dose as long as she wants, 4 is not a limit, Most people find their "maintenance dose" where goal weight has been reached, and no longer experiences appetite suppression, somewhere between 7.5-15.

Finally, UGL tirz is not quite as effective as pharma. It's very likely 20-30 is the actual equivalent to 15mg pharma in efficacy.

Suggest you find a kit with 30mg vials for cost effectiveness.

Finally, make sure you reconstitute in a way that makes each dose .5ml (or more) in volume, not less.

 

[Jeffholio5]

I've gotten several orders from Marcus, all well packaged, and only one delayed shipping issue. My only question is, has anyone else used the tirzepatide with any success? My wife went through 4 vials with little results. Keep in mind, she did not change her eating habits much and did very little exercise to help the process, but still. She only lost a total of 6 pounds from 4 vials.

Anecdotally I tried one vial of his tirz in the past, 20mg vial, my standard dose that’s been effective with other ugl suppliers was 2.5mg/week with GAs I did the same dosage protocol and it felt less effective. Seemed to wear off almost completely by day 5 and caused a bit more nausea on day 1 and 2, this was consistent for about a month until I switched back to our other supplier and those sides went away within a week.

 

[PanamaVet]

Anecdotally I tried one vial of his tirz in the past, 20mg vial, my standard dose that’s been effective with other ugl suppliers was 2.5mg/week with GAs I did the same dosage protocol and it felt less effective. Seemed to wear off almost completely by day 5 and caused a bit more nausea on day 1 and 2, this was consistent for about a month until I switched back to our other supplier and those sides went away within a week.

Oddly enough, that's the only thing she reported differently, nausea. Never any appetite supression, only nausea.

 

[Anat]

I’ve been using Marcus’s Tirz since July, and it’s been working well. I didn’t follow the usual medical protocols or @Ghoul advice.

I started with 2.5mg for the first four weeks, then went up to 3mg. Now I’m at 4mg a week.

No side effects and no appetite so far - it’s going great.

 

[Jeffholio5]

Oddly enough, that's the only thing she reported differently, nausea. Never any appetite supression, only nausea.

No idea what causes that because other sources we use rarely experience any nausea, GA has a jano test saying it’s legit and dosed correctly. So not sure if it’s an additive or something else causing it to feel different. Id be curious to hear from others that have used it with success and that it feels the same as their other sources.

 

[Ghoul]

I’ve been using Marcus’s Tirz since July, and it’s been working well. I didn’t follow the usual medical protocols or @Ghoul advice.

I started with 2.5mg for the first four weeks, then went up to 3mg. Now I’m at 4mg a week.

No side effects and no appetite so far - it’s going great.

LOL, you're following the most important aspect, once a week dosing. That is 90% of what constitutes the "pharma protocol".

 

[Anat]

LOL, you're following the most important aspect, once a week dosing. That is 90% of what constitutes the "pharma protocol".

I read your debates with the guy who injects Tirz every day like testosterone for a steady baseline. I agree that once a week is enough. By the way, thanks for all the helpful info on GLP-1 and the vial adapter spike.

 

[Ghoul]

I read your debates with the guy who injects Tirz every day like testosterone for a steady baseline. I agree that once a week is enough. By the way, thanks for all the helpful info on GLP-1 and the vial adapter spike.

The issue about daily dosing concerns taking a "sloppy" copy of a pharma protein drug, which is already much more immunogenic(antibody producing) than the original, and doing the one thing known to worsen that undesired response more than anything else, increasing frequency of exposure.

No, it won't manifest as suddenly feeling ill, or "losing an ass cheek", but much more insidious, slowly manifesting, and potentially very harmful, even lifelong effects.

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/immunogenicity