MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
SubparMarioBro
Member
If you’re going to have cold storage problems, could you just purchase small vials and reconstitute them weekly as a single-use thing? I realize it seems wasteful to throw out half of a 5mg or 10mg vial if you didn’t use the whole thing, but it’s not as if it’s outrageously expensive. Obviously you’ve gotta manage your storage conditions a bit still, jungle communities seems like it could be a problem, but the lyophilized peps hold up fine at room temp. Not sure how things go at higher temperatures.Am I doomed?
I have been taking Tirz inconsistently for the past months. My work constantly assigns me to travel to underprivileged jungle communities with no electricity - cannot bring my meds.
- November 16 (new vial) - 2.5mg -
- November 25 - 2.5mg -
- December 25 (new vial) - 2.5mg -
- January 2 - 2.5mg -
- February 15 (new vial) - 2.5mg -
- February 22 - 2.5mg -
- March 13 (new vial) - 2.5mg -
- March 19 - 2.5mg -
The days I marked with stars are the injections that I felt lots of appetite and food noise suppression, literally for the whole week!!! But when February came, it just stopped working for me. I'm really worried that I blew my chances as a good responder and what if I built up some immunity to tirz.
This April they finally found a replacement for me to do the field work, so I'll be able to do Tirz more consistently.
I’d wager a guess your doses are low and inconsistent so you aren’t really building up any concentration of the drug. A lot of folks don’t get any effect at the levels you’re at.
When orforglipron finally comes to market you’ll have a good jungle-ready solution. Not a peptide so should be easy to handle.
explodingHeart
Member
After 3 weeks and using about 10mg sema of the very cloudy Chinese semaglutide, I decided to filter and use more.
This time it passed through the chinese .22mm PES filter easily and was able to filter 9ml without too much trouble. I stopped short of clogging the filter becauase I always wanted to have a fresh filtered batch.
Data point for you. Simply waiting 3 weeks made it much easier to filter. Why? Perhaps you can give your theory.
Ghoul
Member
Aggregates adsorb (stick) to container walls more easily than monomers because they have a much larger surface area to interact with the glass. Since they're stuck in the vial that probably lowered the amount of them in solution so there weren't as many to clog the filter.
When they're really large you can see little spots of "gel" on the vial walls.
Wrapping up week 2 of 4 on 10mg Tirz. Last week I was using SSA, this week it’s GA - honestly, didn’t notice much of a difference between the two.
What’s interesting is that 10mg actually feels weaker than 7.5mg did in some ways. But overall, I feel better - no post-injection fatigue like before, and I’ve had no problem hitting my calorie targets.
I’ll keep tracking how things go. Next step: 12.5mg, then 15mg. After that, I might switch to Reta or even try stacking Reta with Tirz. Not sure if that’s the smartest idea, but hey… we’ll find out.
What’s interesting is that 10mg actually feels weaker than 7.5mg did in some ways. But overall, I feel better - no post-injection fatigue like before, and I’ve had no problem hitting my calorie targets.
I’ll keep tracking how things go. Next step: 12.5mg, then 15mg. After that, I might switch to Reta or even try stacking Reta with Tirz. Not sure if that’s the smartest idea, but hey… we’ll find out.
Ghoul
Member
Of you could just discover you've met your goals at 15mg Tirz, reach homeostasis, feel nothing, and stay at that dose enjoying the the long term benefits like those on the pharma protocol do for years....
Yeah, but where’s the chaos in that? Just hitting 15mg, feeling stable, and cruising into long-term health like a responsible adult? Sounds… peaceful. Terrifying. I need at least a little self-experimentation and mild panic to keep things interesting!
Has anyone else felt extreme soreness after tirzepatide?
I had been on semaglutide over a year ago. Eventually switched to tirzepatide and did well on it. Recently though I was doing mazdutide to see what that was like. Since QSC is gone I can’t find anywhere to stick with maz. I decided to go back to tizepatide . I started low at 2.5mg injected yesterday. Today I feel like I got hit by a truck. I am sore absolutely everywhere. It hurts to touch my body. It doesn’t feel like aches from an illness. It feels like I did the biggest work out of my life and all my muscles are screaming. I didn’t have this side effect at all with anything I’ve done before.
It’s not a deal breaker, but im wondering who else experienced this.
I had been on semaglutide over a year ago. Eventually switched to tirzepatide and did well on it. Recently though I was doing mazdutide to see what that was like. Since QSC is gone I can’t find anywhere to stick with maz. I decided to go back to tizepatide . I started low at 2.5mg injected yesterday. Today I feel like I got hit by a truck. I am sore absolutely everywhere. It hurts to touch my body. It doesn’t feel like aches from an illness. It feels like I did the biggest work out of my life and all my muscles are screaming. I didn’t have this side effect at all with anything I’ve done before.
It’s not a deal breaker, but im wondering who else experienced this.
Your tirzepatide or injection water is contaminated. Your body is fighting off the contamination, which is why you're feeling weak. If it's only mild, you'll experience muscle weakness, joint pain, maybe a headache, or a slight fever. If it's severe, you'll have to spend a lot of time on the toilet over the next few days.
Let’s be real - very few people actually throw it out at 30 days. If it’s legit Pfizer bac water, you’re probably fine using it until it’s finished. I do the same myself.
That 30-day rule is more for clinical settings like hospitals, where there’s a higher risk of cross-contamination, multiple users, and different environments. In a clean personal setup, as long as you’re being careful, it’s not a big deal.
Yes, that's true. I mix BA myself. A 100ml mixture of BA costs me €1.89. Every time I mix a new vial of semaglutide, I make a new 100ml of BA. Otherwise, it would have been eight weeks, and I'd have some concerns. I don't think much will happen even after eight weeks, although countless tests show that most refrigerators in private households are dirtier than toilets. At least microbiologically.
It’s gotten awfully quiet around here - either everyone hit their goal weight or decided GLP-1 is yesterday’s news.
Just checking in: I’m wrapping up week 3 on 10mg of Tirz, and honestly, I think I found my sweet spot. No struggles with calories, bloodwork looks perfect, no fatigue… everything just clicking.
Still planning to push it up to 15mg though, because why not? Curiosity is undefeated.
Honestly, Tirz is easily the best thing I’ve ever used. Without question, it’s taken the #2 spot in my book - right after good old testosterone.
Just checking in: I’m wrapping up week 3 on 10mg of Tirz, and honestly, I think I found my sweet spot. No struggles with calories, bloodwork looks perfect, no fatigue… everything just clicking.
Still planning to push it up to 15mg though, because why not? Curiosity is undefeated.
Honestly, Tirz is easily the best thing I’ve ever used. Without question, it’s taken the #2 spot in my book - right after good old testosterone.
Thye're not as "novel" anymore; we all know they work, we all use them now. I don't think we've had something this "magical/ground breaking" in a very, very long time.
I heard people say it works more by mentally making you less inclined to eat rather than phisically suppressing your appetite? is that true? if so it would be very usefull to generally reduce craving without making you unable to eat. with tirz for a while I had zero inclination to eat but I was eating so little it wasn't good for muscle. Now that I lost weigt is stable the appetite is back but thinking about food all the time sucks. I will increase my tirz but I think the same will happen, I'll get a bit leaner and then the fold noise comes back, maybe cagrilitide could help that? I don''t even want to loose too much more weight, like 5-8lbs at most. I just wanna eliminate the food noise so I can be in a better mood
Yeah, every Sunday like clockwork. Sometimes if something came up, I pushed it to day 8 or 9, but mostly it’s every Sunday.
I’ve always had pretty good control over my appetite, even before starting, so I never really had issues with crashes, food noise, or crazy hunger showing up around day 5–6 like some others mention. It’s been smooth for me all the way.
phenominal34
Banned
That’s what I was curious about, I’ve switched to every 6 days now.
Hey bro DM me ill tell u where to go to smaller increments of what your looking for
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