MESO-Rx
Anabolic Steroids
Giant Semaglutide Thread (and other GLP-1 / GIP agonists)
- Thread starter Doodle
- Start date
I used a local weight loss clinic…..started 2.5 then went to 5mg hit a plateau after 5 months then started using ugl Reta which i currently use to maintain current weight
Astartes
Member
Zero actual studies indicate this from what I understand. It’s (to date) more news media hype
SmallTitsIRL
Member
This is the end of the line using Reta for me, which is a shame, cause I have half a kit RT30 I got from SSA in August.
I loved using it, dieting is easy, I don't have craving, I don't think about food. Bulking is easy, I don't fuck it up, I don't think about food, I stick to the plan. Smoking weed? It's perfect, I don't have to indulge in a 5k calorie meal.
Honestly is a miracle drug for someone that was fat growing up and always had issue dieting long term and keeping the weight off.
Now, why it's over for me? At 2mg weekly, my RHR is in the 90s usually 95-99 range. I dislike that very much. Sleep gets a bit fucked from it. FBG is always in the 100s, which is normal due to glucagon, HbA1c is good but honestly seeing 105 FBG every morning is scarier than seeing HbA1c in range every 3 months.
What am I going to do now? Use 40mg+ of Nicotine daily, which doesn't affect my RHR or my FBG due to long-term exposure. And deal with the mental sides using huge amounts of drugs. Like no one should do.
What does the future hold for me? I'll be back to experiment with RT, that's for sure but for the time being, no GLPs, at least until next cut, where I will use Tirz/Cagri instead of RT.
For those curious, I've done bolus dose, and ED pinning of RT. Same shit. Don't come with your "but but pharma does..." idc.
Love you all, not equally. Don't forget Cardio and diet over anything, GLPs are just a tool. And @Ghoul was right about prefering Tirz>RT
I loved using it, dieting is easy, I don't have craving, I don't think about food. Bulking is easy, I don't fuck it up, I don't think about food, I stick to the plan. Smoking weed? It's perfect, I don't have to indulge in a 5k calorie meal.
Honestly is a miracle drug for someone that was fat growing up and always had issue dieting long term and keeping the weight off.
Now, why it's over for me? At 2mg weekly, my RHR is in the 90s usually 95-99 range. I dislike that very much. Sleep gets a bit fucked from it. FBG is always in the 100s, which is normal due to glucagon, HbA1c is good but honestly seeing 105 FBG every morning is scarier than seeing HbA1c in range every 3 months.
What am I going to do now? Use 40mg+ of Nicotine daily, which doesn't affect my RHR or my FBG due to long-term exposure. And deal with the mental sides using huge amounts of drugs. Like no one should do.
What does the future hold for me? I'll be back to experiment with RT, that's for sure but for the time being, no GLPs, at least until next cut, where I will use Tirz/Cagri instead of RT.
For those curious, I've done bolus dose, and ED pinning of RT. Same shit. Don't come with your "but but pharma does..." idc.
Love you all, not equally. Don't forget Cardio and diet over anything, GLPs are just a tool. And @Ghoul was right about prefering Tirz>RT
bananafeet
Member
Hey boss it ain't over till the fat lady sings.
You can use a low dose of metoprolol ER (25mg) to blunt the glucagon effects on RHR. Maybe even a low dose SSRI will blunt the signalling to the strawberry tart.
As for the fasting blood glucose Metformin ER about 1000mg before sleep will drop the BG down to low levels. It's a glucose disposal agent and reduces gluconeogenesis from amino acids. So your protien in the diet goes further.
Keep in mind weed is highly progestogenic and that will probably give you insulin resistance like progesterone does.
It sucks SSA is gone. They were getting good towards the end.
SmallTitsIRL
Member
Hi big boss,
I tried Nebivolol didn't do anything for my RHR, might have to source some Metoprolol, not sure if they act via the same pathway will have to investigate.
I'm using Metformin 1000mg before bed aswell, and FBG still in the 105s. I do know weed acts that way, thus only on a cruise and trying to maintain other than that I avoid weed like the plague.
At some point I'll experiment with RT again, probably sooner than I'd like. But for the time being I feel it's the smartest decision.
SSA were getting close to QSC level.
Quick question, when are you sharing your bananafeet with the community?
bananafeet
Member
To be honest I didn't like Retatrutide. I'm back on semaglutide.
I grew up eating until I couldn't anymore. Semaglutide makes my stomach fill easy so it's the best dieting tool for me. Tirz makes me feel drawn. It makes my blood glucose too low.
Metoprolol is not as fancy as nebivolol. But it works better for rate control of the heart (PVCs, tachycardia).
You need to consider a background noise of stress or anxiety could be adding to the mix of stress driving up the heart rate. I know this because I only got my heart rate down when I had a mental health crisis and ended up on anti depressants (the are better anti anxiety meds to be honest).
Anyway after that my RHR dropped a heap. Even on cycle.
Yes weed is not progestogenic I fucked up. It raises prolactin. Maybe by reducing testosterone or dopamine? I don't know but it messes with the gonadotropins.
Source: Redirecting
SmallTitsIRL
Member
Same, I grew up eating like a dickhead, and many times when stressed I eat like 2 dickheads. Honestly, I use RT just because it makes everything easier, specially maintaining the weight lost.
My HR used to be low 40s when I didn't use RT, some I may be super sensitive to Glucagon, or my liver is just clean and the Glucagon simply raises my sympathetic system instead of raising glucose (?)
Honestly, I should avoid weed at all costs year round. My prolactin has always been high (MRI confirmed that I don't have anything on my pituitary gland, and there's no macro-prolactin), but honestly it's just too good for my mental wellbeing.
SnowyMiami
Member
Forcing your basal metabolic rate higher (high RHR) may be why people lose more weight on Reta than Tirz despite weaker hunger control. Forcing it back down with another drug kind of defeats the purpose but this is bodybuilding where the answer to all questions is more drugs.
SmallTitsIRL
Member
You are correct to a certain extent.
Your heart beating at 95bpms is extremely high and doesn't burn many more calories than if it was in the 60s.
And your RHR being 95 for long periods of time is not healthy at all, let's not overlook that.
Now RT does not directly increase heart rate, but the glucagon may cause that, if your 400lbs fat 50% body fat, while you're losing weight you have the benefits of reta aswell as the benefits of losing weight.
Me being 11-14% body fat I do not have the health benefits of losing body fat.
And yes being a bodybuilder or living the life style is having a small pharmacy in my room, because I'd rather take a drug than have an health problem, which is crazy because I'm pinning steroids and research chemicals (which reta is one, and thus not yet approved)
If you haven’t dropped Reta yet, you could try adding 10mg of ivabradine per day. It should help bring resting heart rate down from around 90-100 bpm to 70-80 bpm. That’s how it worked for me. Just be aware it can make cardio tougher, since it becomes harder to push your heart rate up during training.
SmallTitsIRL
Member
I was recommended that aswell from somewhere else. But honestly it's time to get big and I'm kinda tired of pinning, so 1 less injection is always good
frofrank
Member
Whats your RHR like when you weren't on Reta? That seems really high for someone who I'm assuming is a pretty good athlete at 11-14% BF. When I started reta mine ticked up about 5-7ish but when I introduced GH it was another 10 has been annoying so don't know if your on GH as well I bet that could be a big needle mover.
Mines been slowly coming down as I'm doing more and more cardio and losing fat ( on a massive 120+ pound journey rn)
I do take Nebiv on days I have my pre workout too late or else i'm sitting in bed at 100 trying to fall asleep, sucks that doesn't work for you let me know how ivabradine goes i'm looking to try it as well although its a little pricier than Nebiv.
SmallTitsIRL
Member
I'm lean-ish at, which I assume is 13-15%, lower ab veins + quad veins, but a bit of fat in lower glutes and a bit of love handles.
Before reta my RHR was low 40s, or low 50s if I ate too much the day before. GH didn't change my RHR only my BP went up by 6-10 points which then Telmisartan got it under control.
Last reta pin was last Monday, my RHR today was 83 so a 15 point decrease in 6 days. But I also started 2.5mg Nebi on Wednesday.
Let's go mate keep up the weight loss journey!
Similar threads
