Jonny35
New Member
I've been thinking about SMP too, and your experience is very inspiring. It was especially interesting to hear that even barbers don't notice the difference. how long does the effect stay fresh?
MESO-Rx
Anabolic Steroids
Hair Loss
- Thread starter billydidit
- Start date
Ghoul
Member
Well worth having it checked out. I was low normal, got on T4, and saw a noticeable difference within 6 weeks. That's not enough for growth to be noticed, but the reduction in shed must've made the difference. Feel much, much better too. Far more energy.
Lost my hair for other reasons in my early 20s some years ago. Shaved it off, owned it and now I'm in my late 20s and I still miss my hair every damn day. I bought into the lie that you start to like it someday, nah, losing your hair is really shit.
So if any of you can prevent it, keep your hair gents.
So if any of you can prevent it, keep your hair gents.
pills:
a small amount of Finasteride: 1/2mg every other day
daily biotin pill
topicals:
every other day a bit of topical rosemary and mint oil
a little topical minoxidil every day
The key is to use both at the same time and REALLY rub it into your scalp. Apply Minox first, then apply the natural oils.
Lost 90% of my hair end of 2022 from covid and gear. It all came back using the above after 4 months.
If you want even faster results, add a little bit of red light therapy to top of head 3-4 times a week, 10 minutes at a time, along with the more potent pill anti oxidants (especially astaxanthin)
No need to go mental and use RU or Dutasteride
a small amount of Finasteride: 1/2mg every other day
daily biotin pill
topicals:
every other day a bit of topical rosemary and mint oil
a little topical minoxidil every day
The key is to use both at the same time and REALLY rub it into your scalp. Apply Minox first, then apply the natural oils.
Lost 90% of my hair end of 2022 from covid and gear. It all came back using the above after 4 months.
If you want even faster results, add a little bit of red light therapy to top of head 3-4 times a week, 10 minutes at a time, along with the more potent pill anti oxidants (especially astaxanthin)
No need to go mental and use RU or Dutasteride
Speaking from experience. You're pretty lucky if that's all you had to do to regain a lot of hair loss.
AlexDavis43
Member
You ever try sitting with a red/infrared light on your scalp for 10 minutes? Pretty big pain in the ass.
Wow...sounds exhausting buddy...
MAGA
New Member
Daily dutasteride took care of it for me mainly. Also stopped using Primo and switched to masteron whist dropping my testosterone dose
Photon
Member
Sharing this here in case someone may benefit.
I believe most people here are either on RU58841 or Pyrilutamide (KX-826).
The IC50 values of Ru58851 is 100nM vs Pyrilutamide 0.28 nM.
This means Pyri is significantly stronger at binding to androgen receptors.
However Pyri is also significantly more expensive than RU...theres also no UGL Chinese sources selling it here. For the amount you pay, you can get RU from a Chinese source here, dump a whole lot of it on your head daily and pray that it works. I believe Q does not plan to carry it either which means it's unlikely other vendors would.
RU is usually dosed at 5-8% whereas Pyri is dosed at 0.5-1%.
There's pretty much no trials published for RU on human beings whereas Pyri is undergoing Phase 3 in China.
In the latest trials for Pyri @ 0.5% twice daily, it showed statistical significance in improvements vs baseline but no statistical improvements vs placebo (tldr: it's useless). However this does highlight that Pyri is safe for long term as compared to RU (we dont know).
They are now doing a long term trial on Pyri 1% @ twice daily which will end in 2027, which is expected to have significantly better results than the 0.5% (or not?).
While they undergo trials..it seems like they are already selling this directly to consumers as a cosmetic product on Amazon (lol). The 0.5% version is ~70USD a month and 1% version ~130USD. It will last longer if you use it 1x a day vs 2x as per the trials. For reference, the 0.5% version is sold on minoxidilmax for 105USD before factoring in shipping. The plus side for us is that buying from them directly is cheaper than buying from 3rd party vendors..It is sold as KX-826 by Koshine on Amazon.
PS: I have not tried Pyri, I am currently on RU (Doesn't seem to work..maybe my batch was made too long ago?). I plan to switch over once my last bottle of RU is finished. If anyone has tried both RU & Pyri..please do share your experiences. I gain nothing from this post.
I believe most people here are either on RU58841 or Pyrilutamide (KX-826).
The IC50 values of Ru58851 is 100nM vs Pyrilutamide 0.28 nM.
This means Pyri is significantly stronger at binding to androgen receptors.
However Pyri is also significantly more expensive than RU...theres also no UGL Chinese sources selling it here. For the amount you pay, you can get RU from a Chinese source here, dump a whole lot of it on your head daily and pray that it works. I believe Q does not plan to carry it either which means it's unlikely other vendors would.
RU is usually dosed at 5-8% whereas Pyri is dosed at 0.5-1%.
There's pretty much no trials published for RU on human beings whereas Pyri is undergoing Phase 3 in China.
In the latest trials for Pyri @ 0.5% twice daily, it showed statistical significance in improvements vs baseline but no statistical improvements vs placebo (tldr: it's useless). However this does highlight that Pyri is safe for long term as compared to RU (we dont know).
They are now doing a long term trial on Pyri 1% @ twice daily which will end in 2027, which is expected to have significantly better results than the 0.5% (or not?).
While they undergo trials..it seems like they are already selling this directly to consumers as a cosmetic product on Amazon (lol). The 0.5% version is ~70USD a month and 1% version ~130USD. It will last longer if you use it 1x a day vs 2x as per the trials. For reference, the 0.5% version is sold on minoxidilmax for 105USD before factoring in shipping. The plus side for us is that buying from them directly is cheaper than buying from 3rd party vendors..It is sold as KX-826 by Koshine on Amazon.
PS: I have not tried Pyri, I am currently on RU (Doesn't seem to work..maybe my batch was made too long ago?). I plan to switch over once my last bottle of RU is finished. If anyone has tried both RU & Pyri..please do share your experiences. I gain nothing from this post.
How was Mast vs Primo with hairloss?
MAGA
New Member
Primo made my hair thin, it also tanked my e2.
I switched to Mast E a month after stopping Primo (to let it out of my system), and no shedding at all, if anything had a bit more density come back. Currently on 700mg of Mast E for the last 10 weeks and no hairloss, very stable for me.
Damn...that's awesome
AlexDavis43
Member
Seems a little quick to see noticeable differences in hair density but I'm pro-hair preservation so rock on.
Ghoul
Member
Men have to look in the mirror, and think, "This is as good as it's going to get. Will I be happy to see my hairline recede from here?". If the answer is, "No" take action to keep what you've got.
I study this subject a fair bit and unless I am incorrect there’s a few things my research has shown and please correct me with the studies if not.
1. Dutasteride is the nuclear option having a half life of 5 weeks opposed to Finasteride half life of 5-6hrs. I would not advise taking Dut over Fin as a first ever.
2. The studies on Dut are not 1mg other than prostate but for hair it’s 0.5mg daily.
3. Dut blocks the 2 aspects of 5AR, Fin blocks only 1. Again, safety recommends trialling the lesser drug first to see if that’s enough imho.
4. Minoxidil is NOT a DHT blocker. It was a blood pressure medication and allows good blood flow to the scalp which causes the hair to receive nutrition, oxygen etc and strengthen the hair and follicle.
5. Dut, Fin and Min can bring on a ‘dread shed’ as they cause the follicle to push out the thin hair to regrow another so be aware it can get worse on the recommended dosages before it gets better and given the time length it takes to regrow hair it can be a 1.5year event ‘if’ they are working for you.
6. Topical Fin and Min can lesson the systemic 5AR inhibition so being that less is better, 5AR and DHT are awesome and we need them, you might want to use that first over ‘oral’.
7. I would trial one thing first, like Fin topical as we all know that we can fly blind not knowing what’s doing what when we add more than one thing in in trials.
8. Regarding Nizoral shampoo, it’s the Ketocanozole 2% (not less than 2%) which the study to block DHT. I use this twice weekly leaving sit on the scalp for 5min or more. It can dry your scalp out but is also good against acne.
I’m 50yo and have no history of MPB, but many men begin thinning at 50yo anyway. As I started taking up the test only mildly past 250mg weekly I had diffuse thinning pretty bad. I experimented with 0.25mg of oral Fin EOD for 2 weeks then ED for another 2 weeks, then 0.5mg Fin EOD and went back to 0.25mg daily but I would highly recommend you feel it out specifically looking for a lessening in sexual desire as well as any dull aches in your gonads which I had both even at that low dosage. When that occurs I stop taking it and then go back on when clear. I have had significant success over 3 months of doing this and thicker hair and no more shedding. Obviously as I take up the gear I’ll need to readjust dosages and protocol to suit:
I want to keep my DHT in check, not nuke it personally. Less pharma to achieve the results is safety imho.
I hope that helps and please correct me where I’m wrong if so, I’m always learning and hate to say anything that isn’t correct, great post btw and very necessary for those of us which want to keep our hair.
Okay. That firsst post is 15 years old. Billydidit, do you still have your hair?
Ghoul
Member
Bill died three years ago from cardiovascular disease. No report from the funeral director on the state of his hairline at that point.
How's your blood pressure?
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