MESO-Rx
Anabolic Steroids
Heart Health
- Thread starter GeezerPeformance
- Start date
BamaCrazy
Banned
If you read the sources for that article provided you will see that the Limitations indicate the science is still not settled.
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Limitations
The Master@Heart study was limited to male individuals and did not provide insights on the exercise dose–response relationship in women. For statistical power, we only included men as the risk of coronary artery disease is significantly lower in women. All participants of the Master@Heart study were of White ethnicity, so our results may not be extrapolated to other ethnicities. All athletes denied using illicit performance-enhancing drugs that might induce or accelerate coronary atherosclerosis. However, no laboratory tests were performed to exclude this possibility. The primary endpoint from the Master@Heart study was investigated in a cross-sectional design. Therefore, a definitive causal relationship between endurance exercise and coronary artery disease cannot be made. We applied stringent inclusion criteria in order to minimize the influence of traditional cardiovascular risk factors. However, we did not perform blood sampling or blood pressure monitoring prior to study inclusion. Nevertheless, we do not believe that the higher prevalence of coronary plaques in athlete was influenced by occult arterial hypertension or dyslipidaemia as blood pressure was similar between groups and athletes had even more favourable lipid profiles than controls. Multiple comparisons were performed between lifelong athletes, late-onset athletes, and controls which may increase the risk of Type 1 errors. Finally, lifetime training load was assessed using questionnaires rather than continuous tracking of training logs over time. We do assess training load as part of the prospective follow-up of all study participants, such that we will be able to disentangle exercise intensity and duration and their relationship with coronary atherosclerosis in the future. We cannot exclude that some athletes may have temporarily interrupted exercise training during their lifetime. Nevertheless, superior aerobic capacity and lowest body fat percentage provide indirect evidence of superior training levels in the athletic population.”Stormwallace
New Member
Interesting. Thanks for sending. As a healthcare provider I would hesitate sharing this with some patients who may interpret it as “it’s dangerous to do hard workouts so I’m just going to take it easy”. Also, hard to quantify “intense” exercise when there’s so much variability. I have friends who consider 10 minutes on the elliptical intense.
Stormwallace
New Member
Saw this. Studies like this are so difficult to conduct. Hard to find a big enough group with matching variables. Obviously a big takeaway is the stability of the plaque and interpreting CaC score. High CAC score in someone who’s exercised their whole life way different than a sedentary person. Thus vigorous exercise still outweighs risk
Ghoul
Member
Of course. Everything in context.
I tend to limit to 3 references, but it's enough to get an overview of the developing science on this despite being more out there if you are curious.
It's not unreasonable to think existing hypertension played a role in the damage, even if not present at the time of the exams.
Something similar to the evidence of kidney injury in steroid users. There's often signs of hypertension damage in other organs, despite normal bp at the time kidney problems are discovered.
AlexDavis43
Member
Yeah, exactly
Seeing some guys worried about overtraining I can only shake my head in silence
The study on CAC scores still said they have lower numbers of cardiac events. That's what we're actually trying to avoid.
The other studies like copied below are measuring ultra endurance athletes. Their study group was marathons, ulta marathons, iron man, etc.
pubmed.ncbi.nlm.nih.gov
I don't think these studies actually mean anything even to ultra endurance athletes. The rest of us that think a 10k is long, are far away from seeing anything adverse.
The other studies like copied below are measuring ultra endurance athletes. Their study group was marathons, ulta marathons, iron man, etc.
Potential adverse cardiovascular effects from excessive endurance exercise - PubMed
A routine of regular exercise is highly effective for prevention and treatment of many common chronic diseases and improves cardiovascular (CV) health and longevity. However, long-term excessive endurance exercise may induce pathologic structural remodeling of the heart and large arteries...
pubmed.ncbi.nlm.nih.gov
I don't think these studies actually mean anything even to ultra endurance athletes. The rest of us that think a 10k is long, are far away from seeing anything adverse.
Ghoul
Member
The study on CAC scores still said they have lower numbers of cardiac events. That's what we're actually trying to avoid.
The other studies like copied below are measuring ultra endurance athletes. Their study group was marathons, ulta marathons, iron man, etc.
Potential adverse cardiovascular effects from excessive endurance exercise - PubMed
A routine of regular exercise is highly effective for prevention and treatment of many common chronic diseases and improves cardiovascular (CV) health and longevity. However, long-term excessive endurance exercise may induce pathologic structural remodeling of the heart and large arteries...
I don't think these studies actually mean anything even to ultra endurance athletes. The rest of us that think a 10k is long, are far away from seeing anything adverse.
Despite the limits of these studies, I think this is a useful reminder that regardless of regulate exercise and a high level of fitness, it's not a free pass to ignore regular monitoring of cardiovascular health even if you're lifestyle, in theory, puts you in the lowest risk group.
This irreversible damage had to be a nasty surprise and they would've taken steps to avoid it had they known it was happening.
Even 20 years ago, I'm sure there would've been a way to maintain endothelial health while still keeping up the same level of training.
Ghoul
Member
Damn typos gotta proofread before hitting post, lol
