HGH eod, IGF1 levels

[hghlover]

I'd like to hear from people who have ran HGH every other day at similar doses as you would have every day. For instance 4 iu, but eod instead of daily.

Looking at blood work, does it cause a significant drop in IGF 1 levels as compared to dosing it every day?

I'm thinking about having either two or three off days a week, for instance having monday/wednesday/friday as off days, but I'm unsure if it will make IGF 1 plummet, as opposed to running it every day?

 

[BrockSamson42]

Im sure somebody who has ran it this way will chime in, but ED is more beneficial for IGF. EOD is better for HGH levels itself.

 

[GuerillaPete]

Im sure somebody who has ran it this way will chime in, but ED is more beneficial for IGF. EOD is better for HGH levels itself.

I think maybe you have it backwards.
Igf level i would say are the same as long as the weekly dose is the same.
I use 5 on 2 off with the same weekly dosage and i like it more then eod or ed protocol seems to have les side effects with best effect.
Eod might be better or the same on building muscle
Ed seems better for fat loss .
5 on 2 off seems the best overall in my experience .

 

[hghlover]

@Type-IIx Could you perhaps chime in buddy?

 

[Burly]

Hgh ed vs eod

Hi guys i need your help with hgh.what you thing is the best protocol for hgh 4 iu 5/2 or 10 eod 5on/2off i was thinking to split the dose like that: Morning : 2iu hgh +2 iu hunulin r + 800mg carnitine inj. Before or post workout 2iu hgh+ 15iu humulin r If you want heko me thank you

thinksteroids.com

 

[Type-IIx]

@Type-IIx Could you perhaps chime in buddy?

There is a reduced increase to IGF-I with q.o.d. vs. q.d. administration at the same weekly total dose.

 

[GuerillaPete]

There is a reduced increase to IGF-I with q.o.d. vs. q.d. administration at the same weekly total dose.

You mean eod and ed right?

 

[hghlover]

There is a reduced increase to IGF-I with q.o.d. vs. q.d. administration at the same weekly total dose.

I wonder if this could be somewhat counteracted by upping the total weekly dose within the EOD protocol? My reasoning for EOD is alleviating insulin resistance.

 

[Type-IIx]

You mean eod and ed right?

eod & ed are brospeak I was just using the medical abbreviations that mean the same thing.

 

[Type-IIx]

I wonder if this could be somewhat counteracted by upping the total weekly dose within the EOD protocol? My reasoning for EOD is alleviating insulin resistance.

That is a reasonable justification or rationale that is served by thrice weekly administration.

It cannot be counteracted in the sense that it will always be true that daily administration > alternate day administration at the same weekly total dose.

You just have to decide whether improved insulin sensitivity is worth the diminished Δ IGF-I.

There is another benefits to consider, too, though. For example, daily pinning is more burdensome than thrice weekly.

 

[Burly]

Growth hormone therapy in GH-deficient adults: continuous vs alternate-days treatment - PubMed

In the present report, we have compared 12 months of rhGH therapy given daily (D) at the beginning and then on alternate days (A) to 20 subjects with severe adult-onset GH deficiency (GHD). Aim of the study was to establish whether the lower frequency injection regimen is as effective as the...

pubmed.ncbi.nlm.nih.gov

Efficacy and Safety of Weekly Somatrogon vs Daily Somatropin in Children With Growth Hormone Deficiency: A Phase 3 Study

AbstractContext. Somatrogon is a long-acting recombinant human growth hormone (rhGH) in development for once-weekly treatment of children with growth hormone de

academic.oup.com

 

[hghlover]

That is a reasonable justification or rationale that is served by thrice weekly administration.

It cannot be counteracted in the sense that it will always be true that daily administration > alternate day administration at the same weekly total dose.

You just have to decide whether improved insulin sensitivity is worth the diminished Δ IGF-I.

There is another benefits to consider, too, though. For example, daily pinning is more burdensome than thrice weekly.

Your input is really appreciated. My fasted blood glucose has been in the higher end for months now, and I'm not seeing impressive results with metformin, even at 2g daily. I think I'll try and go with EOD HGH dosing.