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Does high and low E2 levels always cause ED? Do you really need to take an AI when going on Test?
There is a wonderful invention called google.
This question has been answered 1000 times and now 1001
I told you.You didnt listen me.It is about estrogen and estrogen receptors.You need Femara.half tab per 3 days for 2 or 3 months.Last week of Femara >start Nolvadex and continue nolvadex 3 more weeks after Femara.Totally 4 weeks Nolvadex.This will save you from estrogenic side effects.And femara will refresh your estrogen receptors.But you may lose some hair and can break your tendoms cuz of Femara.Be careful about this.Femara is your answer,arimidex should help too but Femara will %100 refresh you
Maybe your situation with high E2 is analogous to those who have experienced big E2 spikes from using HCG.
All of that HCG stimulation ramps up testicular aromatase activity and you end up with high E2. The same thing could happen with high LH.
Just sayin'.
Exogenous T might not spike E2 like driving the testicles hard with HCG/LH
Nah mean?
MAIS is only diagnosed in normal phenotypic males, and is not typically investigated except in cases of male infertility [18]. MAIS has a mild presentation that often goes unnoticed and untreated [15]; even with semenological, clinical and laboratory data, it can be difficult to distinguish between men with and without MAIS, and thus a diagnosis of MAIS is not usually made without confirmation of an AR gene mutation [5]. The androgen sensitivity index (ASI), defined as the product of luteinizing hormone (LH) and testosterone (T), is frequently raised in individuals with all forms of AIS, including MAIS, although many individuals with MAIS have an ASI in the normal range [5]. Testosterone levels may be elevated despite normal levels of luteinizing hormone [15][20][24]. Conversion of testosterone (T) to dihydrotestosterone (DHT) may be impaired, although to a lesser extent than is seen in 5?-reductase deficiency [3]. A high ASI in a normal phenotypic male [45], especially when combined with azoospermia or oligospermia [5][7], decreased secondary terminal hair [26], and / or impaired conversion of T to DHT [3], can be indicative of MAIS, and may warrant genetic testing
I never have in 3+ years of TRT. In fact, after reading this forum and ATM for those same 3+ years, dicking with my estrogen scares the shit out of me. No thanks.Do you really need to take an AI when going on Test?
I told you.You didnt listen me.It is about estrogen and estrogen receptors.You need Femara.half tab per 3 days for 2 or 3 months.Last week of Femara >start Nolvadex and continue nolvadex 3 more weeks after Femara.Totally 4 weeks Nolvadex.This will save you from estrogenic side effects.And femara will refresh your estrogen receptors.But you may lose some hair and can break your tendoms cuz of Femara.Be careful about this.Femara is your answer,arimidex should help too but Femara will %100 refresh you
I always said from the beginning that I had downregulated my androgen receptors and I kind of proved it.
So, you downregulated receptors by AAS and it caused MAIS?
I just don't understand, were you overall normal before AAS? If yes (your problems started after cycle?), then seems steroids CAN cause MAIS symptoms in some form (no congenital, whatever)? Or you will be treating the wrong thing?
Are you going to get genetic testing or you just need diagnosis to start testosterone shots? Dr. Scally mentioned that only T, LH results are not enough.
I never have in 3+ years of TRT. In fact, after reading this forum and ATM for those same 3+ years, dicking with my estrogen scares the shit out of me. No thanks.
I don't want to sound redundant but I found this very interesting and want to clarify some things. So before you ever touched testosterone, naturally you were at 1000ng/dL of testosterone and still exhibited symptoms of low testosterone?
What have you heard about AI's that scare you? I've heard of scary stuff with those hair loss prescriptions but I haven't heard really anything negative about AI's.
I'm not using hcg. Not using anything. My E2 is now normal and I feel no different. It's not an E2 issue.
When I first came her last year I was looking on advice of my hormones because I came off a Test E cycle and became limp. My dick wouldn't work. I did a 9 month enanthate cycle and became like this after coming off.
My Test levels were good. In the upper range but in November I was given a complete hormonal panel and found out my LH was high. High LH means that my pituitary thinks my T is low. I always said from the beginning that I thought I had downregulated my androgen receptors and this high LH level kind of confirmed it but things didn't make sense. It's not heard of right?
Structure (a member of this forum) came on here, saw my bloodwork and that I had symptoms of low T. He said to me, "I think you could have MAIS" At first I didn't believe it but then started reading up more and more on it and this totally defines me 100%. I have LH and High T nothing else can explain it but this:
Mild androgen insensitivity syndrome - Wikipedia, the free encyclopedia
