How long can I take clen for?

[Liter O' Test]

Title.

I want to know if I can take a moderate/low dose for months?
what the risks are?
how common this is?
I think guys run clen their whole prep, months are not uncommon?
I understand it will lose its effectveness, but it surely cant be that rapidly?

This is not a thread for things about diet or 2 week on bro science
or random anecdotes of a friend of a friend you saw on reddit 5 years ago, or about the heart regarding dumbasses who ran 100mcg+ on adderal/tren/cardio/no bp meds
I've been BnC for a very long time but never felt the need to add a weight loss drug in a cut
I dont know anything about clen despite taking gear for a decade, so if anyone can fill me in on some anecdotes
or general practices etc.
Also I think I need clen this time around because I was on beta blockers (metopolol) for the past 3 years and i think that caught up with me
( good news is that my heart rate has been permanently reduced since ive been off them, since Feb)

I just want to run some clen to get the gears turning so to speak, Ive had my carbs and calories reduced greatly for about 6 weeks,
I've made a lot of progress, but I'm not making the progress I'm used to , my metabolism just isnt going as fast as it was even just last summer

Ive read a lot about clen, but i only stumble on advanced discussion of how it burns fat etc, and im missing the whole foundational aspect of it,
of how to run it and generally how guys use it

I'm thinking 8 weeks tapering up from 20mcg up to like 60mcg-80mcg. Im not trying to like actually get any sides, just get the ball rolling and get my metabolism back..

thanks for reading

yes I have DNP , no I havent tried it, yes i know its more effective.
I just dont want to run it for 7-10 days and then spend another week bloated. like ive just been cutting too long to go back to holding water in my face.
like ive said before, Im not fat fat and i am getting weightloss already, and i usually have a good metabolism. so i feel like i just need a little assistance to get things firing, i have a feeling ill be a hyperresponder to clen or any metabolism/fat loss drug for that matter
@Ghoul

 

[Ghoul]

hey man, if someone dumps out 1,000 40ug clen tablets and decides to pop all of them, maybe, ya know.. darwinism and all that

I think highest I've seen reported was 10,000, with raws, thought mcg and mg was the same.

Guy was out of hospital in 2 days, were signs of some heart muscle cell death, but otherwise lived to tell the tale.

 

[buzzingonaas]

I think highest I've seen reported was 10,000, with raws, thought mcg and mg was the same.

Guy was out of hospital in 2 days, were signs of some heart muscle cell death, but otherwise lived to tell the tale.

“Man this clen is really expensive but guess that’s the price of getting lean”

Also, goddamn I can’t imagine how he must have felt.. the first day on 40 I feel like i’m tweaking. He must have been seizing up like crazy

 

[Ghoul]

“Man this clen is really expensive but guess that’s the price of getting lean”

Also, goddamn I can’t imagine how he must have felt.. the first day on 40 I feel like i’m tweaking. He must have been seizing up like crazy

What I see mostly in the various reports of clen hospitalizations are folks who think they're going to have a heart attack. likely from an inadvertent "hot pill" in a UGL pack, rush themselves to the hospital, are
treated, monitored. and released. Still sucks ofc.

 

[onlyontrt]

Leave it up to Ghoul to always provide the info i'm looking for.

Wish I came across this before buying UGL Clen 40mcg tabs. Unfortunately might have to roll the dice for a while.

 

[Ghoul]

Leave it up to Ghoul to always provide the info i'm looking for.

Wish I came across this before buying UGL Clen 40mcg tabs. Unfortunately might have to roll the dice for a while.

40's pretty heavy to start with anyway. I'd try half

 

[onlyontrt]

I've used clen for as long as 8 months. Off now.

I'll make the key points succinctly, if you need more details lmk.

"Tolerance" does develop quickly but it's not that simple. Metabolically 80mg of Clen, without prior use, will increase resting calorie burn by 29%, and fat lipolysis (breakdown to fatty acids) by 39%, along with increasing insulin sensitivity and other fat loss enhancing effects.

The tolerance that quickly develops primarily affects the tremors and boosted twitch speed of muscles. This accounts for only a portion of the extra resting calorie burn, and quickly diminishes as you take the same dose. Some users think that's an indication it's no longer working, which isn't accurate. I also thought increased doses to keep the tremors going and the break to reset receptors were necessary to restore the fat loss effects after you reached your max dose and the tremors stopped, but that wasn't actually necessary.

The increased fat metabolism is a direct action of Clen on fat cells, not relying on continued beta receptor sensitivity.

Air passages continue to be opened more than normal, resulting in higher resting calorie burn.

After all, when used as an asthma med it would be taken for years at the same dose. The tremors are considered a temporary side effect when treatment is initiated. No "break" or ever increasing dose is required to keep patients breathing more easily, or as we're trying to induce, additional fat oxidation.

The increased insulin sensitivity is so durable Clen has experimentally been used as a treatment for diabetes. Again, this doesn't fade with tolerance.

So do you lose some of the "free" calorie burn from a lack of tremors and muscles that have increased twitch response? Yes, how much? Not enough to warrant repeatedly going through the stress the tremor stage puts on your body in as you keep cycling over an extended period, in my opinion. The time to reset receptor sensitivity varies from person to person and protocols are all over the place, btw.

Most of the fat loss benefits will continue with sustained use, and the only way to go if you want to use this for a long period to counteract your slowed metabolism. Do something else to burn off what is perhaps 100-200 / day in extra calories from the tremor stage. The biggest benefits are the continuing enhanced lipolysis that will speed fat loss and boost energy, and better glucose control from increased insulin sensitivity. That is largely what "better metabolism" is anyway right?

So for dosing. 40ug twice a day is the asthma dose, proven to be safe for long term use. 80ug twice a day is the highest amount I've found referred to in a long term study (6 months), and those were people weakened by ALS, with no ill effects.

Because of the possible unintentional overdosing with UGL Clen I wouldn't go past 80ug a day, and would usually take that in one dose early in the morning, A split dose is better but no later than noon for the second to avoid insomnia. With pharma I'd be comfortable going up to 80ug twice a day max. Thats me, 40ug twice a day will still be effective. This is all after slow titration and dependent on how you respond. Don't go higher if you don't feel well. You've also got to monitor BP as it can drop too low if you're normal or below already. First time use 20ug for 4 days, then 40ug, 60ug, until you reach your max. Increasing every 4 days or when the tremors ease off.

Although plenty of people have gone to the hospital after taking too much, or ingesting it accidentally (an infant ate 20 tabs, and turned out ok thankfully) or it was used to cut street drugs, documented injury has only been recorded at really high doses, and thankfully very rare. No fatalities as far as I've been able to find. Definitely don't play with raws. It's essentially heart muscle damage from increased heart rate combined with insufficient oxygen supply from the low blood pressure. Again, the highest heart rate is in the tremor stage when the receptors are most sensitive, so even though the doses we're talking about shouldn't put you anywhere near the danger zone, it's another reason to not cycle back into the tremors.

Stay really well hydrated. A lot of the extra energy expenditure is going to be from expelling moisture via breathing. So not only is dehydration bad in general, it'll slow fat loss.

You'll likely experience cramping. I finally realized this wouldn't happen after a long break, I'd be ok for a few weeks, then it would be continuous cramps. A blood test showed depleted taurine. A known effect of clen.. You don't replace Taurine quickly. I think this is happening mostly in the tremor stage (another reason to avoid repeating it) because of taurine's use in nerves and suspect the constant super twitch response was using it up. This isn't something asthma patients typically experience, which reinforces my belief it happens during the repeated tremor stage when cycling. Whatever causes it, 1000mg / day Taurine from the first day of Clen was enough to keep them away most of the time. On the rare occasion I felt a cramp coming on I'd take another Taurine cap. Cramps were never a problem after that.

Finally don't take this with a high GLP dose. At 15mg/tirz I think the insulin sensitivity effect of both would combine to induce brief hypoglycemia, since I'd get blurry vision for a few moments. Once I stopped the Clen that effect didn't return.

Reading through this thread again and taking notes as my UGL clen should land in the next week or so. I noticed you said 80ug can increase resting calorie burn by about 29%. This is quite a bit, this is almost like doing an extra cardio session or even better. Is it really that pronounced?

Also, I do have the means of getting pharmacy clen from PCT 24/7. Money isn't much of a concern for me when it comes to health. Would you suggest just throwing away this UGL clen (pharmaqo) and ordering some pharma?

 

[Ghoul]

Reading through this thread again and taking notes as my UGL clen should land in the next week or so. I noticed you said 80ug can increase resting calorie burn by about 29%. This is quite a bit, this is almost like doing an extra cardio session or even better. Is it really that pronounced?

Also, I do have the means of getting pharmacy clen from PCT 24/7. Money isn't much of a concern for me when it comes to health. Would you suggest just throwing away this UGL clen (pharmaqo) and ordering some pharma?

Not a fan of UGL clen, pharmaqo are exceptionally difficult to split, making matters even worse beyond the inconsistency from tablet to tablet.

Unfortunately Sopharma is commonly faked now, so the only pharma grade left is from India pharma (clenbut etc), and Alpha pharma is also excellent. There's a new EU vendor here that carries that line if you're in the EU.

Yes resting rate calorie burn is that dramatic, especially initially. You can lay down and feel your heart rate is significantly higher, body temp rise, and even notice significant dehydration after sleeping from the water vapor exhaled as a result of increased metabolism.

That said, a new GLP / Metabolism study released just a few days ago found initial evidence that resting metabolism via the conversion of white fat to metabolically active brown fat after six months leads to an approximately 20% increase in resting calorie burn after 24 weeks of treatment in humans. Still early days for this aspect of GLP effects, but it was confirmed in mice and the biopsies performed after in earlier studies.

This effect is durable in a calorie deficit, and since short term clen use is in part intended to offset the slowing of metabolism as you cut calories, this may be a much healthier way of increasing "background" calorie burn continuously.*

*We do have a new self appointed QA moderater here at Meso, so take this with a grain of salt until he's had a chance to analyze the data and chime in with his hypothesis @Lexington

 

[onlyontrt]

Not a fan of UGL clen, pharmaqo are exceptionally difficult to split, making matters even worse beyond the inconsistency from tablet to tablet.

Unfortunately Sopharma is commonly faked now, so the only pharma grade left is from India pharma (clenbut etc), and Alpha pharma is also excellent. There's a new EU vendor here that carries that line if you're in the EU.

Yes resting rate calorie burn is that dramatic, especially initially. You can lay down and feel your heart rate is significantly higher, body temp rise, and even notice significant dehydration after sleeping from the water vapor exhaled as a result of increased metabolism.

That said, a new GLP / Metabolism study released just a few days ago found initial evidence that resting metabolism via the conversion of white fat to metabolically active brown fat after six months leads to an approximately 20% increase in resting calorie burn after 24 weeks of treatment in humans. Still early days for this aspect of GLP effects, but it was confirmed in mice and the biopsies performed after in earlier studies.

This effect is durable in a calorie deficit, and since short term clen use is in part intended to offset the slowing of metabolism as you cut calories, this may be a much healthier way of increasing "background" calorie burn continuously.*

*We do have a new self appointed QA moderater here at Meso, so take this with a grain of salt until he's had a chance to analyze the data and chime in with his hypothesis @Lexington

Thanks for the info!

 

[onlyontrt]

So just went from 20mcg to 40mcg UGL (not planning on going any higher until my India pharma comes in) but at both dosages I haven’t felt much of anything. No tremors or anything like that. Not saying it’s bunk though because I am the type of guy who took tren and if it wasn’t for strength increase and shitty bloodwork I wouldn’t have known I was on anything.

 

[xrayphoton13]

Not a fan of UGL clen, pharmaqo are exceptionally difficult to split, making matters even worse beyond the inconsistency from tablet to tablet.

Unfortunately Sopharma is commonly faked now, so the only pharma grade left is from India pharma (clenbut etc), and Alpha pharma is also excellent. There's a new EU vendor here that carries that line if you're in the EU.

Yes resting rate calorie burn is that dramatic, especially initially. You can lay down and feel your heart rate is significantly higher, body temp rise, and even notice significant dehydration after sleeping from the water vapor exhaled as a result of increased metabolism.

That said, a new GLP / Metabolism study released just a few days ago found initial evidence that resting metabolism via the conversion of white fat to metabolically active brown fat after six months leads to an approximately 20% increase in resting calorie burn after 24 weeks of treatment in humans. Still early days for this aspect of GLP effects, but it was confirmed in mice and the biopsies performed after in earlier studies.

This effect is durable in a calorie deficit, and since short term clen use is in part intended to offset the slowing of metabolism as you cut calories, this may be a much healthier way of increasing "background" calorie burn continuously.*

*We do have a new self appointed QA moderater here at Meso, so take this with a grain of salt until he's had a chance to analyze the data and chime in with his hypothesis @Lexington

Is this any glp or was it a certain one? I'm currently running tirzepitide with clen. Are you saying I may not need the clen?

 

[Ghoul]

Is this any glp or was it a certain one? I'm currently running tirzepitide with clen. Are you saying I may not need the clen?

This white fat to brown fat effect was found across a wide spectrum of GLP receptor agonist drugs: exenatide, lixisenatide,
liraglutide, dulaglutide, albiglutide, and semaglutide.

While they didn't look at Tirz and Reta, I think this is an effect applicable to all GLP-1 receptor agonists, including those.

Exogenous GIPs add another aspect to this, since they "open the door wider" for energy to move into or out of fat storage. Normally, you only get a GIP boost in a fed state, to facilitate storage of excess calories. Since Tirz(and Reta) have a GIP component, in a calorie deficit fat is lost faster than lean tissue improving body composition.

I don't think Clen is worth the stress on your system, long term, when running a GLP / GIP year round, even at non-weight loss doses induces metabolic changes that safely facilitate faster fat burning lipolysis, along with providing a big package of other health benefits.

Basically, long term use of Clen for its direct action on fat lipolysis, has, in my opinion, been replaced by GLPs. The higher the dose of GLP you can tolerate without driving your appetite too low for your goal weight, the better, since the non-.appetite reducing metabolic benefits all increase proportionate to the dose.

 

[BP_6]

I've been taking pharm grade clen at 20mcg/day for many months now. Was taking 40mcg/day. All depends on the dose and your tolerance. Likely doing very, very little for fat loss but it is not expensive and at 20mcg it gives me zero sides. Just for that little .1% boost.