HYB (Best Service and Product - International Shipping)

[oldgrey]

We have communicated with the new freight company and began to restore the acceptance orders (because of the particularity of Oils and OILS, so the delivery will be delayed, and we must ensure the safety of transportation!) Everyone is delayed by 30usd to December 15, China time. At the end of the number, each person is limited to only once.

Can you clarify this, I think there is a typo - Everyone is delayed by 30usd to December 15, China time. At the end of the number, each person is limited to only once.

 

[bighunanballs]

Skip Tirz and go straight to Reta
You won’t regret it!

Lol jokes aside tirz or reta for sure

Man honestly the Reta has me eating like a fat piece of shit. No appetite suppression at 8mg/wk. Tirz at 7.5mg killed my appetite and will to snack 100%. Although I'm eating clean on reta it's definitely nothing like Tirz for app suppression if that's what you're after.

 

[max187]

Man honestly the Reta has me eating like a fat piece of shit. No appetite suppression at 8mg/wk. Tirz at 7.5mg killed my appetite and will to snack 100%. Although I'm eating clean on reta it's definitely nothing like Tirz for app suppression if that's what you're after.

100% agreed. If appetite suppression and fat loss are the main goal then Tirzepetide is king. If you are already jacked with muscle and looking to just take the edge off of hunger cravings and get the other glucagon related benefits then Retatrutide is great. I can definitely eat way more food on Retatrutide compared to tirz.
Tirz at 7.5mg per week is way stronger suppression than 9mg of per week Reta for m not even comparable.

 

[Trenbolonetax]

Man honestly the Reta has me eating like a fat piece of shit. No appetite suppression at 8mg/wk. Tirz at 7.5mg killed my appetite and will to snack 100%. Although I'm eating clean on reta it's definitely nothing like Tirz for app suppression if that's what you're after.

Oh yeah reta has the least appetite suppression for me. I can still eat like a fat piece of shit and I have been lol.

I’ve not tried sema, but Tirz definitely slowed gastric motility and suppressed appetite more than Reta.

I'm enjoying Reta cuz I can eat, i believe the glucagon component helps ameliorate fat gain in surplus, and then still get some BG control but just not quite as good as Tirz.

Reta still quiets the food noise for me almost as good as Tirz, but I just don't get the physiologic "full" feeling as quick

 

[bighunanballs]

Oh yeah reta has the least appetite suppression for me. I can still eat like a fat piece of shit and I have been lol.

I’ve not tried sema, but Tirz definitely slowed gastric motility and suppressed appetite more than Reta.

I'm enjoying Reta cuz I can eat, i believe the glucagon component helps ameliorate fat gain in surplus, and then still get some BG control but just not quite as good as Tirz.

Reta still quiets the food noise for me almost as good as Tirz, but I just don't get the physiologic "full" feeling as quick

Ya I'm definitely still very slowly recomping on reta so no complaint with fatloss. I also don't seem to be as fatigued. Reta is perfect for clean bulking, recomping or cutting without the extreme app suppression. Tirz lost me the bulk of the weight but now that I'm around 15% bf Reta is doing nicely

 

[Trenbolonetax]

Ya I'm definitely still very slowly recomping on reta so no complaint with fatloss. I also don't seem to be as fatigued. Reta is perfect for clean bulking, recomping or cutting without the extreme app suppression. Tirz lost me the bulk of the weight but now that I'm around 15% bf Reta is doing nicely

Very well put. Think there is a logical progression of these GLP1s based on someones starting place and goals.

 

[RekTest]

I chose Sema after discussing it with @Ghoul yesterday. I'm primarily after the psychological edge it might give on the addiction side, which is primarily GLP mediated. Sema is the strongest binder of that of the three, so has potentially the better effect considering my use case. I don't struggle with appetite, I struggle with just psychological urges to eat even when not hungry. So seeing as Sema seems the most beneficial, that's where I'm starting. If I see bad sides etc, i'll swap to Tirz.

It might be that it turns out just a difference on paper, but theory suggests not. Regardless, I 'needed' some GH at the same time, so it also lined up being better for cost effectiveness considering.

I can tell you, from personal experience you wont be disappointed with the GLPs vs DNP.

Ive ran DNP 3 times iirc, though quite some time ago by now, and high doses (750 crystal)
I can tell you GLPs are fucking magic and nothing compares to them.
Im on Tirz and it completely changes, mentally how you view food.
I was a fat piece of shit 3 months ago and had problems with eating, bad habits that were hard to quit, in the past I would diet and get cravings for ice cream every 6 ish days, on Tirz I was able to do a harsher (plain) diet and not get any cravings.
DNP just kills you, where as on GLPs life is just easy.. you go through the day just not thinking about food or feeling hunger rumbles, like I drink a huge protein shake in the morning that takes me all the way to dinner, which even by then my stomach isn’t talking to me, and only if I go til the next morning will I hear a little something, but nothing compared to cutting naturally… id get hunger pains terrible to the point of my stomach hurting i was so hungry and Im eating LESS on Tirz and feeling worlds better, I dont even feel like Im cutting.
I have a theory Tirz turns something off in your brain so it doesnt register your in a deficit and just keeps everything going as normal… but Im not Ghoul smart to even know if this is a thing, but from what I am experiencing its just a thought I have.

 

[rexy]

I can tell you, from personal experience you wont be disappointed with the GLPs vs DNP.

Ive ran DNP 3 times iirc, though quite some time ago by now, and high doses (750 crystal)
I can tell you GLPs are fucking magic and nothing compares to them.
Im on Tirz and it completely changes, mentally how you view food.
I was a fat piece of shit 3 months ago and had problems with eating, bad habits that were hard to quit, in the past I would diet and get cravings for ice cream every 6 ish days, on Tirz I was able to do a harsher (plain) diet and not get any cravings.
DNP just kills you, where as on GLPs life is just easy.. you go through the day just not thinking about food or feeling hunger rumbles, like I drink a huge protein shake in the morning that takes me all the way to dinner, which even by then my stomach isn’t talking to me, and only if I go til the next morning will I hear a little something, but nothing compared to cutting naturally… id get hunger pains terrible to the point of my stomach hurting i was so hungry and Im eating LESS on Tirz and feeling worlds better, I dont even feel like Im cutting.
I have a theory Tirz turns something off in your brain so it doesnt register your in a deficit and just keeps everything going as normal… but Im not Ghoul smart to even know if this is a thing, but from what I am experiencing its just a thought I have.

Thanks for detailing your experience. I knew what I'd be getting back into with DNP as I've used it successfully quite a few times. Hence why I edged myself towards just not going through that again when I could give the GLPs a go.

Long term I plan to move towards Tirz, and if I find Sema to be problematic I'll shift pretty quickly. I do think Tirz is quite clearly the better overall compound. I'm just keen for that enhanced GLP binding as I need the psychological edge as much as possible. Clearly it still happens with Tirz but it takes a higher dose and is not as strong at that particular receptor (hence the dosing differences). So whilst I might get the same or enough psychological effect from it, it might not be for months or at a dose outside the clinical ranges, whereas with Sema it should technically be sooner.

So for the first go with a GLP where I need to see my responses and have to go by theory, the Sema made sense based on my particular focus. Especially because it's cheaper and the side effects should show me pretty quickly whether I need to move on or not.

 

[zombiesauce]

So odd to read all your replies. Tirz had only a slight appetite supression effect for me, I switched over to Reta and at 5mg a week was able to cruise into my show with my appetite controlled very well.

 

[rexy]

So odd to read all your replies. Tirz had only a slight appetite supression effect for me, I switched over to Reta and at 5mg a week was able to cruise into my show with my appetite controlled very well.

Reading your response, I'm glad i've started with Sema. It seems like individual variability can be large in response to these - I've seen @Sampei comment on Tirz giving him +10-15bpm on RHR and i'm susceptible to that. So I think at least if I get whacked by Sema sides, I'll have the tested the 'roughest' of the bunch to begin with. But I also definitely do not want more HR burden than I already have from HGH + AAS, so if Tirz does that to me it's a non-starter too. We'll see.

 

[UncleBuns]

So odd to read all your replies. Tirz had only a slight appetite supression effect for me, I switched over to Reta and at 5mg a week was able to cruise into my show with my appetite controlled very well.

Seems like each person reacts quite different to each one. Maybe it has to do with quantity and sensitivity of different receptors people have? The GLP's interact with completely different systems in the body and Even though two different ones May agonize the same receptor they do it with a different intensity.

Check this out:



Lower number means the drug more intensely agonizes that type of receptor.

 

[ZyzzReincarnate]

Seems like each person reacts quite different to each one. Maybe it has to do with quantity and sensitivity of different receptors people have? The GLP's interact with completely different systems in the body and Even though two different ones May agonize the same receptor they do it with a different intensity.

Check this out:

View attachment 306718

Thats what I was looking for. Thanks!

 

[rexy]

Seems like each person reacts quite different to each one. Maybe it has to do with quantity and sensitivity of different receptors people have? The GLP's interact with completely different systems in the body and Even though two different ones May agonize the same receptor they do it with a different intensity.

Check this out:

View attachment 306718

Lower number means the drug more intensely agonizes that type of receptor.

Great find!!! where's that from?

 

[UncleBuns]

Great find!!! where's that from?

Credit goes to @egruberman

View attachment 298482

Units are nanomolars, lower is better. The relative percentages are hard to express, but <1 is "high" 1-100 is "moderate" and >100 is "low".

Source for sema:

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide - PubMed

Liraglutide is an acylated glucagon-like peptide-1 (GLP-1) analogue that binds to serum albumin in vivo and is approved for once-daily treatment of diabetes as well as obesity. The aim of the present studies was to design a once weekly GLP-1 analogue by increasing albumin affinity and secure...

pubmed.ncbi.nlm.nih.gov

Imma skip the others for now unless anyone cares. Much of this data is non-specific and proprietary.

 

[rexy]

Credit goes to @egruberman

Thanks a lot for that, that is super useful in my scenario. The downside: I can no longer put off reading through each page in that thread lol.

 

[krvuxn]

Tirz doesn't suppress my appetite at all, but sema does. Even at 0.5mg sema. Max dose of tirz and I still wanted to eat like a horse.

 

[ZyzzReincarnate]

MWU HAHAHAHAHHAHA

I HAVE SOME RETATRUTIDE ON THE WAY

NOBODY CAN STOP ME NOW!!!

 

[Cipio]

@Yura(HYB) The new Oils and orals tests?

 

[RAW95]

@Yura(HYB) The new Oils and orals tests?

I would like to see as well the tests from the orals without the split.

 

[Benf15harp]

Day 3 attempt 3
@Yura(HYB)
Do you test your raw materials?