wow that is awesome. thank you. I had to stop golfing and fishing in the spring and the fall because I would lose all blood circulation in my fingers.
A couple of toes on one foot would get this low level torture all winter long. I saw 6 specialists, not one mentioned the possibility of Raynaud's.
When I stumbled on a description of Raynaud'sI realized it was similar to my symptoms. 20% of adults apparently have it, mostly undiagnosed, and a low priority for doctors since it's seen as a non threatening annoyance. Coincidentally I started on low dose daily cialis around this time, and (after a month) the symptoms weren't nearly as bad.
While I was researching Cialis and Raynaud's, I came across a pharma trial of Cilnidipine, proposed to be the first Raynaud's med to be released.
Turns out cilnidipine is a cheap generic Japanese developed BP med exclusively available in Asia, not available in the US (simply a quirk of history), and being repurposed as an extremely expensive "orphan drug" for Raynaud's.
As it happens, Cilnidipine is an incredible BP med, with a number of positive side effects.
A big one is that it uniquely blocks calcium N channel (norepinephrine) channels
TLDR this blunts the "fight or flight" adrenaline induced construction of blood vessels, the heart of Raynaud's, which also blunts "stress related" blood pressure increases and other physical responses to stress without any sedation whatsoever.
It also prevents edema, a common side effect of Amlodipine, the most widely used calcium channel blocker BP med.
It's a life changer, 20mg daily combined with daily cialis has totally resolved my Raynaud's toe symptoms.
It's also become a very popular BP med here on Meso, with many of us stockpiling a few thousand pills in case supply gets cut off.