I'm creating this thread separately from any other similar/possibly intersecting threads - as it's a little far out.
So anyways. For many years I took hydrocodone daily. A decade in fact 20-30mgs/day. Most of that time I never felt any skin itching sensations. One day, I was chatting with a friend who was talking about how miserable he gets when he pops a hydrocodone because he starts itching like crazy.... Even with that said I was kinda like well maybe I feel a little something from time to time but NO NOT ME. Then as the years passed I started to notice it too... BLA BLA and finally just like everyone else, I was cut off of my opioid script around 2015 and have not since had the luxury of worrying about any of this.
But here's the thing. I have something going on right now that actually merited a doc writing me some steady hydrocodone for a week or so (NOT YOU CANT HAVE ANY LOL).... I am immediately noticing the itching sensation coming and going in various skin areas... I can also tell that its not a ghost or false neurological sensation as most would think. I AM 100% SURE of this because where ever these itching sensations occur, I can scratch lightly and catch something unknown but noteworthy under the fingernail THAT IS COMING OUT OF THE SKIN.... The texture and composition feeling like ranging anywhere from dead skin to hard like sand. As small as these particles are they are definitely responsible for the itch... In fact most times its identical to scratching your face and ripping the ass ends off of the demodex mites hanging out of your facial hair pores. Hell I may even try to save some larger finds and put them under a microscope. Still we are talking about itching anywhere on the body as it may crop up, but at the same time its appears more prevalent on the face and other hairy areas like forearms etc... Places where these are normally found... (yes I just showed you what is on your face - my bad)
Can ya believe these are normal and in everyone's face?!! Now you know what fascial skin mask creams are for. Right?! And don't you find it funny that they never even market via this known fact!?. Shit all you would have to do is hold a seminar on demodex mites, tell them your cream removes these, and you would be rich over night. But thats another conspiracy for another day.
Now perhaps currently, whatever I am scraping off is normal mites, or simply comes from keratin, or some kind of sebaceous/ cholesterol buildup in the skin. And I am sure you can have mites like those in any hair pore. BUT for what reason is the opioid triggering this now notable physical sensation and urge to scratch...
And if there is any truth to any of this then wouldn't it be a good thing overall?. Or does the Govt. not want you to realize parasitic skin activity ensuing?
** Logically minded, the application of an opioid pain modulator should in fact numb the skin and you should be less likely to notice anything foreign.. Right?
But then again blood plasma opioid drug concentration levels will also cycle UP and DOWN; and is this effectively dynamically resetting skin CNS nerve BASELINES and this reset allowing for an opportunity to recognize foreign or overgrown sensations as the blood values go up and then back down? Succinctly, you go to numb as a new normal, and then when you come back down in between dosing, you now become aware of any abnormal skin activity that had otherwise built up, or snuck in under the radar via the cloaking action of TIME?
1. So then really is the hydrocodone simply somehow triggering a change in the physical touch sensations on the skin alerting you to scratch any benign, over-built but normal, or foreign object? Even if just normal skin mites?
2. Or is the hydrocodone FORCING FOREIGN LIVING BIOLOGICS out of the skin and why all of the sudden they come to your attention.?
IS THE OPIOID ACTION PHYSICALLY FORCING FOREIGN BODIES (Living or not) OUT OF THE SKIN AND VIA SOME UNKNOWN MECHANISM or simple 'side-action" of the effect of the meds from a purely physical standpoint??
IS the action of the opioid forcing a manual micro-muscular reaction as CONTRACTION in the skin pores via the same system that controls "chill bumps" per say. And is this forcing things out?
Did people have healthier or cleaner skin when using opioids?
And with further regard to the THREAD TITLE as it relates to "Anti-parasitic" action. What exactly might the opioid be doing deeper down and throughout the body in terms of PHYSICAL NEUROLOGICAL awareness, reaction, and physical response?
What effect on internal cellular growth, body system cancer cell awareness, even deep DNA level activity could the fluctuations of the MU receptor modulation be eliciting to a positive result? MU receptors will be where ever you can feel pain or pleasure obviously, but is this even a possibly unidentified action of Opioids not understood by science yet. I mean obviously there was little motivation to research opioids a single day beyond finding them. As once you are in pain and find they work its pretty much CASE CLOSED - I WANT THAT!!! Right? LOL
BUT WHAT POSITIVE net effect would we now register in the concept of "drug tolerance" and could you possibly see how the body's ability to adjust to new norms FORCING dose changes to maintain desired effects now synergizing to create an extension of this proposed positive effect on Opioid MU receptor agonism and modulation.!? As not only are normal metabolic changes occurring daily ranging from dietary influence to physical receptor stimulus, but you have this ever changing receptor level "requirement" to continue to keep the body affected by the drug mechanism. Thus enforcing further positive proposed neurological actions as hypothesized in this post...
Allz I am saying is that its very likely that minimally, opioid induced itching sensations are based on real stimulus and not simply "ghostly" in nature. And what is this mechanism precisely and what is really going on and at what levels throughout the body..?.!
I stop for now.
So anyways. For many years I took hydrocodone daily. A decade in fact 20-30mgs/day. Most of that time I never felt any skin itching sensations. One day, I was chatting with a friend who was talking about how miserable he gets when he pops a hydrocodone because he starts itching like crazy.... Even with that said I was kinda like well maybe I feel a little something from time to time but NO NOT ME. Then as the years passed I started to notice it too... BLA BLA and finally just like everyone else, I was cut off of my opioid script around 2015 and have not since had the luxury of worrying about any of this.
But here's the thing. I have something going on right now that actually merited a doc writing me some steady hydrocodone for a week or so (NOT YOU CANT HAVE ANY LOL).... I am immediately noticing the itching sensation coming and going in various skin areas... I can also tell that its not a ghost or false neurological sensation as most would think. I AM 100% SURE of this because where ever these itching sensations occur, I can scratch lightly and catch something unknown but noteworthy under the fingernail THAT IS COMING OUT OF THE SKIN.... The texture and composition feeling like ranging anywhere from dead skin to hard like sand. As small as these particles are they are definitely responsible for the itch... In fact most times its identical to scratching your face and ripping the ass ends off of the demodex mites hanging out of your facial hair pores. Hell I may even try to save some larger finds and put them under a microscope. Still we are talking about itching anywhere on the body as it may crop up, but at the same time its appears more prevalent on the face and other hairy areas like forearms etc... Places where these are normally found... (yes I just showed you what is on your face - my bad)
Can ya believe these are normal and in everyone's face?!! Now you know what fascial skin mask creams are for. Right?! And don't you find it funny that they never even market via this known fact!?. Shit all you would have to do is hold a seminar on demodex mites, tell them your cream removes these, and you would be rich over night. But thats another conspiracy for another day.
Now perhaps currently, whatever I am scraping off is normal mites, or simply comes from keratin, or some kind of sebaceous/ cholesterol buildup in the skin. And I am sure you can have mites like those in any hair pore. BUT for what reason is the opioid triggering this now notable physical sensation and urge to scratch...
And if there is any truth to any of this then wouldn't it be a good thing overall?. Or does the Govt. not want you to realize parasitic skin activity ensuing?
** Logically minded, the application of an opioid pain modulator should in fact numb the skin and you should be less likely to notice anything foreign.. Right?
But then again blood plasma opioid drug concentration levels will also cycle UP and DOWN; and is this effectively dynamically resetting skin CNS nerve BASELINES and this reset allowing for an opportunity to recognize foreign or overgrown sensations as the blood values go up and then back down? Succinctly, you go to numb as a new normal, and then when you come back down in between dosing, you now become aware of any abnormal skin activity that had otherwise built up, or snuck in under the radar via the cloaking action of TIME?
1. So then really is the hydrocodone simply somehow triggering a change in the physical touch sensations on the skin alerting you to scratch any benign, over-built but normal, or foreign object? Even if just normal skin mites?
2. Or is the hydrocodone FORCING FOREIGN LIVING BIOLOGICS out of the skin and why all of the sudden they come to your attention.?
IS THE OPIOID ACTION PHYSICALLY FORCING FOREIGN BODIES (Living or not) OUT OF THE SKIN AND VIA SOME UNKNOWN MECHANISM or simple 'side-action" of the effect of the meds from a purely physical standpoint??
IS the action of the opioid forcing a manual micro-muscular reaction as CONTRACTION in the skin pores via the same system that controls "chill bumps" per say. And is this forcing things out?
Did people have healthier or cleaner skin when using opioids?
And with further regard to the THREAD TITLE as it relates to "Anti-parasitic" action. What exactly might the opioid be doing deeper down and throughout the body in terms of PHYSICAL NEUROLOGICAL awareness, reaction, and physical response?
What effect on internal cellular growth, body system cancer cell awareness, even deep DNA level activity could the fluctuations of the MU receptor modulation be eliciting to a positive result? MU receptors will be where ever you can feel pain or pleasure obviously, but is this even a possibly unidentified action of Opioids not understood by science yet. I mean obviously there was little motivation to research opioids a single day beyond finding them. As once you are in pain and find they work its pretty much CASE CLOSED - I WANT THAT!!! Right? LOL
BUT WHAT POSITIVE net effect would we now register in the concept of "drug tolerance" and could you possibly see how the body's ability to adjust to new norms FORCING dose changes to maintain desired effects now synergizing to create an extension of this proposed positive effect on Opioid MU receptor agonism and modulation.!? As not only are normal metabolic changes occurring daily ranging from dietary influence to physical receptor stimulus, but you have this ever changing receptor level "requirement" to continue to keep the body affected by the drug mechanism. Thus enforcing further positive proposed neurological actions as hypothesized in this post...
Allz I am saying is that its very likely that minimally, opioid induced itching sensations are based on real stimulus and not simply "ghostly" in nature. And what is this mechanism precisely and what is really going on and at what levels throughout the body..?.!
I stop for now.