In relation to Pre-loading;

[OmL]

I’ve never er pre-loaded for a cycle. But for my next one i plan on doing so.

When ore loading, are there any extra precautions to take? I plan on preloading 10 or so at a time, storing them in a zip lock bag in my little safe (with an open alcohol wipe in the bag).

Is it this simple?

 

[Sector]

You mean pre loading syringes with gear?

That should be fine. A lot of people do it that way

 

[Fattyone]

Idk if it matters but moisture can be a problem if you leave any air in the syringe.

 

[BigTomJ]

take into consideration the carrier oil and solvents in the gear you are preloading. as im sure you know some can dissolve the rubber on the plunger.

other than that, my line of thinking is:
Gear from a sterile vial, through a sterile pin, stored in a sterile syringe, is still sterile.

That being said, i personally dont like preloading, I dont see a purpose in regular day to day use, and if its a concern with traveling, im just going to bring the vial and a few pins and swabs with me.

 

[OmL]

take into consideration the carrier oil and solvents in the gear you are preloading. as im sure you know some can dissolve the rubber on the plunger.

other than that, my line of thinking is:
Gear from a sterile vial, through a sterile pin, stored in a sterile syringe, is still sterile.

That being said, i personally dont like preloading, I dont see a purpose in regular day to day use, and if its a concern with traveling, im just going to bring the vial and a few pins and swabs with me.

I accept this as the answer. Thanks man.

 

[laclark89]

take into consideration the carrier oil and solvents in the gear you are preloading. as im sure you know some can dissolve the rubber on the plunger.

other than that, my line of thinking is:
Gear from a sterile vial, through a sterile pin, stored in a sterile syringe, is still sterile.

That being said, i personally dont like preloading, I dont see a purpose in regular day to day use, and if its a concern with traveling, im just going to bring the vial and a few pins and swabs with me.

Yup that's y we store our vials right side up so the solvents dont eat up the rubber stopper or what ever.

I accept this as the answer. Thanks man.

I for sure except this answer, i was thinking about pre loading gh pins and put em in the fridge, but that bac water has alcahol and could probably still damage a plunger.

 

[BigTomJ]

Yup that's y we store our vials right side up so the solvents dont eat up the rubber stopper or what ever.

I for sure except this answer, i was thinking about pre loading gh pins and put em in the fridge, but that bac water has alcahol and could probably still damage a plunger.

im not knowledgeable on the chemistry side to distinguish what types of plastics and rubbers are effected by what type of solvents and to what degree.
That being said im not sure that the benzyl alcohol content would dissolve the rubber.

I know some alcohols can dissolve some plastics and rubbers, but im not sure in BA is one of them, and im not familiar with the rubber typically used in vial stoppers.

@GreenAmine might know more.

personally i agree with you and just stay on the safe side, my understanding of the chemistry is too limited to know whats safe.

 

[GreenAmine]

im not knowledgeable on the chemistry side to distinguish what types of plastics and rubbers are effected by what type of solvents and to what degree.
That being said im not sure that the benzyl alcohol content would dissolve the rubber.

I know some alcohols can dissolve some plastics and rubbers, but im not sure in BA is one of them, and im not familiar with the rubber typically used in vial stoppers.

@GreenAmine might know more.

personally i agree with you and just stay on the safe side, my understanding of the chemistry is too limited to know whats safe.

The rubber portions of syringes and vials are typically made of either chlorobutyl or bromobutyl rubber. I have personally seen data from extractions performed on this material under very harsh conditions (high temp, vigorous stirring, harsh solvents), and we didn't really see much of anything that would be of a safety concern, especially with water-based solvents.

In short: I preload sometimes, and I know what's in there. I'm not worried about it, but I wouldn't blame someone for being extra cautious. Many pharma companies use this material for prefilled syringes.

 

[PaintDrinker]

I typically only preload the night before a pin if I’m mixing 3-4 compounds and don’t want to deal with it in the morning. Don’t see any issues with it in my opinion.

 

[laclark89]

The rubber portions of syringes and vials are typically made of either chlorobutyl or bromobutyl rubber. I have personally seen data from extractions performed on this material under very harsh conditions (high temp, vigorous stirring, harsh solvents), and we didn't really see much of anything that would be of a safety concern, especially with water-based solvents.

In short: I preload sometimes, and I know what's in there. I'm not worried about it, but I wouldn't blame someone for being extra cautious. Many pharma companies use this material for prefilled syringes.

im not knowledgeable on the chemistry side to distinguish what types of plastics and rubbers are effected by what type of solvents and to what degree.
That being said im not sure that the benzyl alcohol content would dissolve the rubber.

I know some alcohols can dissolve some plastics and rubbers, but im not sure in BA is one of them, and im not familiar with the rubber typically used in vial stoppers.

@GreenAmine might know more.

personally i agree with you and just stay on the safe side, my understanding of the chemistry is too limited to know whats safe.

Thanks guys.

 

[Gymbro901]

I’ll pre-load about a week or two’s worth of pins at a time. Never had an issues. I pin with a 27g insulin needle and it’s a slow ass draw from the vial, so I get impatient and would rather just do a batch at a time and back fill with a larger syringe. Just grab a pin from the bathroom drawer in the morning and go.