Increlex?

There is some good information here, as I have very limited knowledge of but in depth experience with IGF-1 Lr3 specifically. I began using it on a whim after procuring enough to experiment with a few years ago - I researched what I could find at the time and just went for it - keep in mind that is was after taking a very long break from any gear use of any kind aside from protein and standard vitamins. I have always weight trained depending on the degree my unfortunate health issues were at any given time.

Long story not so short for those interested - I ended up there after health issues caught up with me & I had to literally fight to survive. Once back on my feet & training for several months I started on Test E at 125mg/wk for 8 weeks. All going great.

I introduced IGF-1 Lr3 at 50mcg into the muscles I was training that day. So 50 each in bi's day 1, 50 in tri's day 2 and so on.

I did this for 6 weeks as I upped my Test to a modest 250 during this time.

For me, there was no denying the hard pumps into the sight injected muscle groups - the next day I could still feel it in delta as I moved to quads for the current day. I loved it & my output in the gym was very positive & fulfilling. Almost as good as my 25 year old angst filled self with unlimited life ambitions. My vascularity was out of this world. I don't spend a ton of time in the mirror but I was enchanted by the places veins were showing up on my body.

However by week 5 I began to have discomfort, like my spleen was rupturing (it happened before, same feeling). I went down to 30mcg per sight with no change. At the end of week 6 I stopped completely (just the IGF).

Without having time to see if the pain & discomfort would subside, I ended up in the ER two days after stopping with a perforated ulcer. It was a nightmare, blood from every single orifice. Major surgeries, in a coma, developed chronic foot-drop from my right knee down, blood clot, 2 blood transfusions & 52 days in the hospital.

I also came out forever a diabetic as it seemed my pancreas issues didn't appreciate that experience either. So ended up with a mass on my pancreas & intestines. Fairly recently that was removed along with part of those organs.

After all that blabbing my point is just to share my feelings on it. I'll never dabble in it again personally. From having to take insulin daily for the rest of my life (which I have to mention stays perfectly in range with my Lantus dose - for those who may see the sweet food I post at times in Nutrition), to having that mass form, it just appears that with the bit of research I've done that a fella in my position is just asking for more trouble here.

I've spoken to many who compete that utilize IGF, GH on top of who knows what else but of course their genetics, personal health along with the concrete commitment they execute perpetually is a whole level from what my humble goals have always been.

Regardless I'm loving learning more about it and everything else for that matter.

And you're 100% 5 weeks of igf did this? I could understand an enlarged spleen and if you ruptured a hernia, but ulcer is strange.

Also , never heard of increlex causing insulin resistance, or was the diabetes after the mass developed on your pancreas?

Never used igf just curious
 
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And you're 100% 5 weeks of igf did this? I could understand an enlarged spleen and if you ruptured a hernia, but ulcer is strange.

Also , never heard of increlex causing insulin resistance, or was the diabetes after the mass developed on your pancreas?

Never used igf just curious
The diabetes was diagnosed after the mass developed.

Also I should REALLY mention, the experience I had & shared is totally based solely on what I experienced combined with mostly my personal research. I had 2 of MANY doctors who I mentioned the IGF to afterward. They did not seem concerned about the short-term use of IGF, only that the prior spleen issue along with my other digestive problems suggested to stay away from it.

I deducted after starting daily insulin it also be best. But I should read what I posted earlier...I know it's too late to add or edit but I am still getting used to the Ambien I was recently prescribed. It tends to make me a bit bonkers on certain nights.
 
MegaDaveMustang, man, that's very unfortunate and really sad to hear that.

Here's the thing, many of folks still believe that IGF-1 LR3/DES is just another, more powerful form of Recombinant Human IGF-1, which is not true. Many research chem and peptide websites are posting misleading info, they try to convince customers that this under-researched peptides are effective and safe by posting links to the studies done on RH-IGF-1. I bet the doctors you talked to didn't even know you were taking Lr3/DES.
RH-IGF-1 binds to Insulin receptors and shouldn't lead to diabetes, if we look up info on increlex we won't see hyperglycemia (diabetes) among potential side effects.
 
The thing to remember with the IGF 1 analogues (des and lr3) is that they are unnatural analogues not found in the human body. IGF 1 (increlex) and HGH is made by our own body every single day. Much safer to take in exogenous form.

I guess the analogues could be seen as research chemical, with unknown long term effects
 
MegaDaveMustang, man, that's very unfortunate and really sad to hear that.

Here's the thing, many of folks still believe that IGF-1 LR3/DES is just another, more powerful form of Recombinant Human IGF-1, which is not true. Many research chem and peptide websites are posting misleading info, they try to convince customers that this under-researched peptides are effective and safe by posting links to the studies done on RH-IGF-1. I bet the doctors you talked to didn't even know you were taking Lr3/DES.
RH-IGF-1 binds to Insulin receptors and shouldn't lead to diabetes, if we look up info on increlex we won't see hyperglycemia (diabetes) among potential side effects.

I would agree. The perforated ulcer still has me wondering if it was due to IGF.

The growth on the pancreas makes sense

Sorry to hear about this @MegaDaveMustang

IGF is a powerful hormone. I believe it's to be blamed for the guts in bodybuilding honestly
 
Belly growth from the IGF1 release from HGH or from increlex?

Most likely the cocktail of insulin/gh/igf, but I believe the igf1 , either increlex or igf 1 lr3, plays a large part. Probably not every bodybuilder uses it, but the one's who do would show loll
 
Our digestive system, specifically the intestines have a high amount of igf receptors and you're literally feeding them
 
Our digestive system, specifically the intestines have a high amount of igf receptors and you're literally feeding them
If it was intestinal growth, then they would not shrink down once these guys retire, but they do, so it is not that. It is not something permanent. Indeed, we have been seeing bodybuilders showing up recently who used to be bloated without the turtle shell gut.

I think it was just poor carb up practices that are getting under control now. Bodybuilders were showing up with bloat, actual gas in their intestines and digesting food in their intestines from massive food carb up and insulin protocols precontest. The coaches are finding ways not to do this anymore, and the competitors are showing up in better condition, too (Big Ramy showed up in such better condition that he took the Mr. Olympia title, but the others were in great condition, too).

Just my two cents
 
I had horrible bubble gut before I discovered that liquid egg whites and my digestive system did not agree. Looked freaking pregnant.
 
I would agree. The perforated ulcer still has me wondering if it was due to IGF.

The growth on the pancreas makes sense

Sorry to hear about this @MegaDaveMustang

IGF is a powerful hormone. I believe it's to be blamed for the guts in bodybuilding honestly
Thank you, yeah I'm just going to stay away from IGF and HGH.

Right now I'm sticking to things that have treated me well since my gut problems started. Just not worth it and if a time comes when I have to drop any other and/or all aas also, so be it.

Until then, I'm feeling pretty great so far.
 
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