Is there any steroid that’s lipid friendly?

Is there any steroid that won’t raise LDL or perhaps not as much as others?
To directly answer, I’d agree that testosterone is the least likely.

I’d also advise you to pay attention to your HDL and High Reactive C Protein. I think it’s very important, if not more important to keep HDL high, than to worry about LDL. If your LDL is high, but your HSCRP shows no low level inflammation, I personally believe you’re in pretty good shape. If you have high LDL and your Hscrp is higher range, I’d look for inflammation culprits in diet, sleep issues, and start looking into healthy ant inflammation strategies.
 
If I stay on 100mg of testosterone replacement everything is fine. Anything more and all the numbers start going the wrong way.

Excellent diet, abs all year long. I’m on 120mg of test and 60mg of deca (both pharmaceutical). I took a calcium test and it came back at 33.7. While this is mild risk I’m 54 and the test stated my artery is that of a 65 year old. With a bad family history and low HDL I don’t want to make matters worse.

Started reducing the carbs a lot and replacing them with healthy fats. Joint inflammation actually went down. Besides occasional headache from very low carb days I fell good. I also started taking baby aspirin.
 
If I stay on 100mg of testosterone replacement everything is fine. Anything more and all the numbers start going the wrong way.

Excellent diet, abs all year long. I’m on 120mg of test and 60mg of deca (both pharmaceutical). I took a calcium test and it came back at 33.7. While this is mild risk I’m 54 and the test stated my artery is that of a 65 year old. With a bad family history and low HDL I don’t want to make matters worse.

Started reducing the carbs a lot and replacing them with healthy fats. Joint inflammation actually went down. Besides occasional headache from very low carb days I fell good. I also started taking baby aspirin.
Have you looked into a statin or PCSK9 inhibitor?
 
Supposedly, there was a steroid called furazabol marketed in Japan that was lipid-friendly and lowered cholesterol:


But this turned out to be a myth.

Well, it did lower total cholesterol but it was only due to the severe suppression of HDL. Not good.
 
Low dose rosuvastatin is surprisingly effective. I got a ~10% improvement in LDL with ezetimibe and another ~30% improvement adding in 10mg rosuvastatin daily. More recently, I've added in bempedoic acid, which is expensive in the US if not covered by insurance, but even cheaper than ezetimibe in the Indian pharmacies. I've also discovered my insurance covers Repatha. With the combo, I have the lipid profile of a child even while blasting 1.5g/wk.
 
Sounds so cap
End of May 2023 lipid profile on the below stack (estimate, doses were bumped around end of May or start of June)

1000mg To 1500mg Test
1000mg To 1500mg EQ
Mast 400-600mg
15-18iu Grey tops/Black tops ED (split into 3x a week)
75mcg T3

This is with Mast added no less. As I said, "solid".
 

Attachments

Last edited:
To directly answer, I’d agree that testosterone is the least likely.

I’d also advise you to pay attention to your HDL and High Reactive C Protein. I think it’s very important, if not more important to keep HDL high, than to worry about LDL. If your LDL is high, but your HSCRP shows no low level inflammation, I personally believe you’re in pretty good shape. If you have high LDL and your Hscrp is higher range, I’d look for inflammation culprits in diet, sleep issues, and start looking into healthy ant inflammation strategies.
Why do you think it’s important to keep HDL high? Isn’t there data coming out showing that HDL alone isn’t that great of a predictor?
 
Low dose rosuvastatin is surprisingly effective. I got a ~10% improvement in LDL with ezetimibe and another ~30% improvement adding in 10mg rosuvastatin daily. More recently, I've added in bempedoic acid, which is expensive in the US if not covered by insurance, but even cheaper than ezetimibe in the Indian pharmacies. I've also discovered my insurance covers Repatha. With the combo, I have the lipid profile of a child even while blasting 1.5g/wk.
How much further did bempedoic acid improve your LDL? I'm in the same spot except I'm im only using 5mg rosuvastatin + 10mg ezetimibe. Planning to add bemp acid in. I've considered Repatha but I don't like the idea of super long half life in case the sides suck.
 
I had a 160 LDL as a natural on no peds. Doctor prescribed rosuvastatin and I added ezetimibe on my last blast of test primo and anavar my LDL was 55
 
These days, it's become a standard practice to prescribe a low dose statin for anyone who gets metformin and the data look really good in controlling cardiovascular disease outcomes. I mention that to say, somewhere along the way, statins became the boogeyman but a small dose (5-10 mg) of the powerful ones (atorvastatin, rosuvastatin) can cover up a whole lot of sins. That's all with negligible risk of any side effect in the vast majority of people.

I was a distance runner as a kid and so I kinda abhor monotonous cardio now, but it's another non-drug means of improving your LDL and HDL numbers while decreasing overall circulating triacylgylcerides. If you keep the intensity low, it won't interfere with your lifting -- hell, it might actually help recovery between sets to be able to get the most out of every breath. The stationary bike also helps with soreness/stiffness the day after heavy legs, too. As un-sexy as it is, it's essentially risk free and has a few different benefits... that's a favorable comparison to almost every other option out there.
 
I had a 160 LDL as a natural on no peds. Doctor prescribed rosuvastatin and I added ezetimibe on my last blast of test primo and anavar my LDL was 55
One of the fucking zaniest things in human biology is the variability in cholesterol. For almost everyone, dietary cholesterol has no impact on serum values... your liver makes so much more than you can eat that diet can't compete. For some people, eating the tiniest bit will throw them through the roof. Still others can't make the number move up or down, even with combinations of strong drugs at high dosages.

There has to be some crazy evolutionary history behind it, because biochemical processes that can kill you don't tend to show as much variability as cholesterol levels do. I'd bet tons of money that, at the very least, the genes that control lipid metabolism have more Neanderthal alleles out in the wild than most other metabolic systems.
 
One of the fucking zaniest things in human biology is the variability in cholesterol. For almost everyone, dietary cholesterol has no impact on serum values... your liver makes so much more than you can eat that diet can't compete. For some people, eating the tiniest bit will throw them through the roof. Still others can't make the number move up or down, even with combinations of strong drugs at high dosages.

There has to be some crazy evolutionary history behind it, because biochemical processes that can kill you don't tend to show as much variability as cholesterol levels do. I'd bet tons of money that, at the very least, the genes that control lipid metabolism have more Neanderthal alleles out in the wild than most other metabolic systems.
I went from out of shape, eating like crap, not working out to working out, losing a bunch of weight, eating all clean food and doing daily cardio. Cholesterol stayed the same 230 total, 160 LDL, 60 HDL definitely genetic
 
Why do you think it’s important to keep HDL high? Isn’t there data coming out showing that HDL alone isn’t that great of a predictor?
There’s a lot of data showing it’s good. I also have a lot of blood test results where I’ve abuse the fuck out of drugs and it’s been tanked.

I have seen a study that show HDL raised by niacin are not beneficial.

But when I really look at what HDL does- to transport cholesterol from tissues back to the liver, my intuition tells me that it’s very important if you’re placing great stress on your body.( like during a blast)

More specifically, it can uptake and return cholesterol to the liver that is stored in the foam cells of atherosclerotic plaques. Thus, reducing the size of the plaque and its associated inflammation.

Let me know if you’ve seen evidence otherwise
 

Sponsors

Latest posts

Back
Top