Ghoul
Member
So what you are saying is vendors should stop applying vacuum to the GH, and just buy the cheapest GH we can find. No point in testing because it might actually be better if the results suck. Got it.
An interesting thing about oxidation damage to rHGH. The study showed that it didn't directly damage the rHGH molecule.
What it did do was make the rHGH much more temperature sensitive, speeding up degradation, leading to aggregation.
Since more rHGH is pulled onto the aggregate, there's loss of active ingredient.
Once this aggregate becomes larger than .22um, it's no longer detected as a contaminant bringing down purity or measured as a loss of rHGH, since there's no way to know how much was in the vial to start with.
So the loss of purity you see in the test, and the huge increase in dimer, is only the tip of the iceberg. There are impurities and lost rHGH in the other side of the filter.
On top of this, the remaining rHGH will degrade faster than it should since it's been oxidized.
