Moda/Armodafinil BP and RHR

[MrGrant]

When taking modafinil and/or armodafinil has your blood pressure and/or resting heart rate gone up?
If so how long do they stay raised after discontinuing?

The blood pressure raise is a known side effect from them and not normally enough to warrant discontinuing (unless your BP is already very high?) but haven't seen any info on how long the effect lasts for.

Thread 'Quick Modafinil note'

Jun 30, 2025

Just FYI with my own experience and I would like to hear others. I have been taking either amodafinil 150mg or Modafinil 200mg for a while now. I know the max prescribed dose of Amodafinil is 250 and 400mg for Modafinil and even up to 600mg in some cases.

So just to see, I have been trying 400mg/day all at once of the Modafinil as I heard people respond differently. For me, it has been a very dramatic difference in terms of effectiveness. Considerably better with 400 over 200. It however has caused my heart rate to rise about 3-5bpm depending on the day and about a 5 point increase...

• BP_6
• Replies: 6
• Forum: Steroid Forum

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• 

 

[bananafeet]

When taking modafinil and/or armodafinil has your blood pressure and/or resting heart rate gone up?
If so how long do they stay raised after discontinuing?

The blood pressure raise is a known side effect from them and not normally enough to warrant discontinuing (unless your BP is already very high?) but haven't seen any info on how long the effect lasts for.

Thread 'Quick Modafinil note'

Jun 30, 2025

Just FYI with my own experience and I would like to hear others. I have been taking either amodafinil 150mg or Modafinil 200mg for a while now. I know the max prescribed dose of Amodafinil is 250 and 400mg for Modafinil and even up to 600mg in some cases.

So just to see, I have been trying 400mg/day all at once of the Modafinil as I heard people respond differently. For me, it has been a very dramatic difference in terms of effectiveness. Considerably better with 400 over 200. It however has caused my heart rate to rise about 3-5bpm depending on the day and about a 5 point increase...

• BP_6
• Replies: 6
• Forum: Steroid Forum

• 
• 

I've been on 200mg Modafinil for a while now. Zero effect on both and I monitor them closely.

Maybe if you take more than that? I've taken 300mg moda and got headaches. Keep in mind I take 25-50mg metoprolol per day and 40mg telmisartan.

 

[ChemBB]

I'm prescribed 400mg Moda a day for idiopathic hypersomnia.

I only take 300mg in the AM unless I'm especially tired, since 400mg for me tends to give headaches and a mild crash later.

There may be some ~5 BPM elevation in RHR, and mild increase in BP.

You have to experiment to find the right dosage for you -- I'd suggest trying 100/200/300mg on consecutive days.

The increase in BP/RHR are transient and due to acute effects of the drug. As soon as serum blood concentrations are low enough your vitals will return to baseline.