My bloodwork results!

[Cdave.aol]

I don't really know, I'd have to guess. My guess is that, with a single dose, there's a substantial period of time that there's an acutal depot of the oil in the muscle which releases the compound by simple diffusion. This partly depends on the surface area of the depot, among other things. The oil will spread as a very thin layer across the length of the muscle fibers, yielding a large surface area.

After a couple of days, this depot will become smaller and smaller, and finally no trace of an actual oil depot in the muscle can be found: the oil will have spread throughout the body and (I suppose) be incorporated in adipose tissue. The steroid will then be dissolved in a larger volume of oil (that of the adipocytes), but with a relatively smaller surface area and thus a slower rate of diffusion. (In absolute terms, of course, the surface area will be larger-but the steroid will be a lot less concentrated.)

This will be increasingly more relevant with "slow" esters, as with shorter/faster esters most of the steroid will already have left the oil depot before it's largely added to adipose tissue. And thus also more relevant with multiple doses, as there's more accumulation.

Edit: this is mostly a brain fart from my side, as I haven't thought this through too much. So perhaps I'll be slaughtered by some nerd with my logic here soon enough.

Is it just me or do glute injections seem to take longer for the depot to reduce in size compared to a smaller muscle like delts?

 

[Type-IIx]

Is it just me or do glute injections seem to take longer for the depot to reduce in size compared to a smaller muscle like delts?

I'm going to put you to sleep with this one HAH

"Injection site may be important because of diferences in tissue composition and blood flow; indeed, i.m. oil-based injections may be more accurately termed intermuscular or intralipomatous. The former reflect the tendency of oil vehicle to distribute along intermuscular fascial planes, whereas the latter depends upon the amount of fat at the injection site (including systematic gender differences) together with needle geometry and anatomy of the injection depot. Intralipomatous deposition of injections with a larger vehicle volume may explain the slower release kinetics of nandrolone decanoate in the gluteal region, as well as the differences from the deltoid site, which has a lower fat content. The higher blood flow in the deltoid, compared with the gluteal, muscle may also be important."

Minto CF, Howe C, Wishart S, Conway AJ, Handelsman DJ. Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle: effects of ester, injection site and injection volume. J Pharmacol Exp Ther. 1997 Apr;281(1):93-102. PMID: 9103484.

 

[RzSco]

I wonder if the amount of scar tissue I have in my glutes due to using them as my sole injection site for about 300+ injections over a few years makes any difference.


For haematocrit, I had the sample taken a couple hours after waking up but I didn't drink anything that morning (for some reason I got confused and included water in "fasting"). I'm not chronically dehydrated, I drink 2-3 litres a day. Is this likely to have influenced my HCT at all?

 

[RzSco]

SHBG 12 and the range is 10-57. Could this have something to do with the relatively low test levels I'm getting per mg injected?

 

[Cdave.aol]

SHBG 12 and the range is 10-57. Could this have something to do with the relatively low test levels I'm getting per mg injected?

You’re definitely a fast metabolizer of test, like myself very low SHBG. I think frequent injections will help that issue. But if you’re taking any orals especially DHT derivatives that’ll definitely crash your SHBG.

 

[gilmarpersonal]

@PeterBond After a cycle of 1000mg of enanthate per week, how many weeks for my testosterone to drop to physiological levels? Thanks

 

[PeterBond]

@PeterBond After a cycle of 1000mg of enanthate per week, how many weeks for my testosterone to drop to physiological levels? Thanks

About 4 weeks.

 

[gilmarpersonal]

About 4 weeks.

So should I start PCT in the fourth week? ThanksSo should I start PCT in the fourth week? Thanks

 

[Ambusher]

Would it be appropriate to take half of the initial dose of Test E for the second and all succeeding does so that the blood levels remain close to the initial dosage? Say you take 500mg the first day and by the fourth day, shouldn't you take take only 250mg? Since the half-life of Test E is roughly 4 days, on the fourth day you will have roughly 250mg of Test E. If you took 500mg of Test E on the fourth day, then you would actually have 750mg. So, in summation, should you take half the amount of the first dose for all subsequent injections so that blood levels remain closer to the initial dosage?