The use of Nizoral for MPB is highly debated, with plausible evidence on both sides of the argument. So, really the larger issue is not how often to use it, but does it actually do anything. Hardly anyone views McNeil's (maker of Nizoral) studies as credible. There is no hard evidence to prove that if Nizoral does exert anti-androgenic properties sufficient to aid in MPB, that the dose schedule used for fungal treatment, which is 2-3x/week, would be sufficient to treat MPB. So, why not use daily? Or in the case of 2%, as often as tolerated. McNeil's bogus study also showed little to no difference in efficacy b/w the 1% & 2%. I opt for the easy to obtain, less irritating, daily use of 1% shampoo. The cream is obviously not as user friendly.
Rex.