Noopept https://en.wikipedia.org/wiki/Noopept
From Wikipedia, the free encyclopedia
Noopept
Systematic (IUPAC) name
N-Phenylacetyl-L-prolylglycine ethyl ester
Clinical data
Legal status
CAS Registry Number
157115-85-0
PubChem CID 180496
ChemSpider 157065
Chemical data
Formula C17H22N2O4
Molecular mass
318.367 g/mol
SMILES[show]
InChI[show]
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Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a peptide promoted and prescribed in Russia and neighbouring countries as a nootropic. The registered brand name Noopept (Ноопепт) is trademarked by the manufacturer JSC LEKKO Pharmaceuticals. The compound is patented in both the US and Russia with patent of Russian Federation number 2119496, US Patent number 5,439,930 issued 8/8/1995.[1] It is sold as adietary supplement in the US and as a medication in other countries.
Mechanism of action[edit]
Noopept Box Front
Noopept blister pack
Noopept is not a racetam (due to not having a 2-oxo-pyrrolidine skeleton),[2] but is generally grouped together in the same category because it shares similar mechanisms of action with the racetam family.[3] When compared to traditional racetams, it has been found to be, according to studies, 1000 times more potent than the prototypical racetam drug,piracetam.[4]
References[edit]
From Wikipedia, the free encyclopedia
Noopept
Systematic (IUPAC) name
N-Phenylacetyl-L-prolylglycine ethyl ester
Clinical data
Legal status
- US: Unscheduled
CAS Registry Number
157115-85-0
PubChem CID 180496
ChemSpider 157065
Chemical data
Formula C17H22N2O4
Molecular mass
318.367 g/mol
SMILES[show]
InChI[show]
Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a peptide promoted and prescribed in Russia and neighbouring countries as a nootropic. The registered brand name Noopept (Ноопепт) is trademarked by the manufacturer JSC LEKKO Pharmaceuticals. The compound is patented in both the US and Russia with patent of Russian Federation number 2119496, US Patent number 5,439,930 issued 8/8/1995.[1] It is sold as adietary supplement in the US and as a medication in other countries.
Mechanism of action[edit]
Noopept Box Front
Noopept blister pack
Noopept is not a racetam (due to not having a 2-oxo-pyrrolidine skeleton),[2] but is generally grouped together in the same category because it shares similar mechanisms of action with the racetam family.[3] When compared to traditional racetams, it has been found to be, according to studies, 1000 times more potent than the prototypical racetam drug,piracetam.[4]
References[edit]
- Jump up^ PatentGenius.com http://www.patentgenius.com/patent/5439930.html
- Jump up^ [unreliable medical source?]http://examine.com/supplements/Noopept/
- Jump up^ Gudasheva TA, Boyko SS, Ostrovskaya RU, Voronina TA, Akparov VK, Trofimov SS, Rozantsev GG, Skoldinov AP, Zherdev VP, Seredenin SB (1997). "The major metabolite of dipeptide piracetam analogue GVS-111 in rat brain and its similarity to endogenous neuropeptide cyclo-L-prolylglycine". European Journal of Drug Metabolism and Pharmacokinetics 22 (3): 245–52.doi:10.1007/BF03189814. PMID 9358206.
- Jump up^ Ostrovskaia RU, Gudasheva TA, Voronina TA, Seredenin SB (2002). "[The original novel nootropic and neuroprotective agent noopept]". Eksperimentalnaia i Klinicheskaia Farmakologiia (in Russian) 65 (5): 66–72. PMID 12596521.
