Opti tropin GH serum and IGF test results

[hexagonal]

Variability in IGF-1 response to HGH is pretty wild. 4IU/day of SRY has mine just a shade over 500. Estrogen was towards the top of the range, but still in it.

 

[hcgfiend123456]

TL;DR ,, i was in a calorie deficit for too long (2years) so my igf1 numbers arent that good for the amount of hgh @5 ius daily , but i have reaped the benefits of hgh besides just a igf1 number, and in my 50's i feel its helped tremendously for recovery as well as lypolosis and lean tissue gain, in last 8 months ive gained 11 lbs of lean muscle mass dropped 2% bf down to 10 % currently confirmed through dexa scan i had Tuesday, and ive only been basically 200 mg test c weekly 5 ius hgh , , Diet and cardio , water etc have been on point also, All Ugl hgh ,,

A calorie deficit for 2 years sounds brutal lol. Being 10% BF sounds sweet though. Trade offs for everything, eh.

 

[Ateam2023]

A calorie deficit for 2 years sounds brutal lol. Being 10% BF sounds sweet though. Trade offs for everything, eh.

i should have just used a glp1 , lol ,, it would have been less of a timeframe, but looking back all this has really just made me more motivated, after i look back at start and current pics ive taken for personal portfolio, it really is Pretty sweet losing 15% bf and gaining muscle and totally recomping my physique, ,

 

[hcgfiend123456]

i should have just used a glp1 , lol ,, it would have been less of a timeframe, but looking back all this has really just made me more motivated, after i look back at start and current pics ive taken for personal portfolio, it really is Pretty sweet losing 15% bf and gaining muscle and totally recomping my physique, ,

Why do you think it would of taken less time if you were taking a glp1? You'd of accomplished more of a deficit?

 

[juicebro]

Some interesting comments from chat gpt

Serum IGF-1 may appear low (or not rise significantly) because a significant portion of IGF-1 is being used locally in target tissues like muscle, bone, or connective tissue, especially when growth hormone (GH) or anabolic steroids are present and muscle-building processes are active.

​

• ~99% of IGF-1 in serum is bound to IGF-binding proteins (IGFBPs) — primarily IGFBP-3, forming ternary complexes with acid-labile subunit (ALS).
• When tissues need IGF-1, these proteins regulate release and uptake.
• In muscle undergoing hypertrophy (due to training, GH, androgens), IGF-1 is actively extracted and used for local anabolic signaling.

Result: High local usage may reduce free IGF-1 or even lower measurable total serum IGF-1 transiently.

• Androgens (testosterone, nandrolone, etc.) and insulin can enhance IGF-1 receptor expression and IGF-1 uptake into muscle.
• The more receptive the tissue, the faster IGF-1 is cleared from circulation into active use.

Result: In highly anabolic states (GH + AAS + insulin + training), you may observe low-normal IGF-1levels despite maximum effectiveness.

Think of serum IGF-1 like fuel in the tank. If you're revving a high-performance engine (training + GH + AAS), the fuel gets used rapidly, so the level in the tank stays low, even though the engine is running at full power.

Indirect Evidence Supporting This​

• Athletes on GH and anabolic steroids often have only moderately elevated IGF-1, yet experience extreme hypertrophy.
• Rodent studies show increased IGF-1 receptor activity and uptake in muscle after GH or testosterone — again, not fully reflected in circulating IGF-1.
• Goldspink et al. (2005): Local IGF-1 isoforms increased after training, but serum IGF-1 levels didn’t match this rise.

 

[hcgfiend123456]

Some interesting comments from chat gpt

​

View attachment 329243

Interesting

 

[25th Bam]

AI as a substance i believe nothing, crashed estradiol from too much AI, a lot. You need healthy estrogen levels for IGF conversion.

I wish I learned this sooner. My first time testing IGF1 after using my first box of generics I tested 229ng/ml with my e2 crashed at 5.1. Made me panic buy a few pens of NGENLA lol. Working on getting my e2 fixed so I don’t waste any more GH

 

[lilhawk]

Far more to results on GH than IGF numbers.

 

[AlexDavis43]

Far more to results on GH than IGF numbers.

Like what

 

[Ateam2023]

Why do you think it would of taken less time if you were taking a glp1? You'd of accomplished more of a deficit?

No , the way the glp1 work is alot more efficient at burning fat and keeping the metabolism in balance , a straight calorie deficit is only part of the bf burning,,

I wish I learned this sooner. My first time testing IGF1 after using my first box of generics I tested 229ng/ml with my e2 crashed at 5.1. Made me panic buy a few pens of NGENLA lol. Working on getting my e2 fixed so I don’t waste any more GH

you know that chasing an igf1 number doesn't mean that the hgh isn't working, ime i have a rather lower igf1 @200 ish , but absolutely reap the benefits( skin, hair, nails, recovery, fullness, vascularity) from the hgh , i was concerned about my lower numbers but realized when testing igf1 i was always in a defecit so that absolutely has something to do with it as well as e2 being in the lower range, but i love the benies i get from the hgh regardless of igf1 number,,

 

[25th Bam]

Why do you think it would have taken less time if you were taking a glp1? You'd of accomplished more of a deficit?

If you run a glp1 like Reta, you can handle a steeper deficit better and get increased energy expenditure as well.

No , the way the glp1 work is alot more efficient at burning fat and keeping the metabolism in balance , a straight calorie deficit is only part of the bf burning,,

you know that chasing an igf1 number doesn't mean that the hgh isn't working, ime i have a rather lower igf1 @200 ish , but absolutely reap the benefits( skin, hair, nails, recovery, fullness, vascularity) from the hgh , i was concerned about my lower numbers but realized when testing igf1 i was always in a defecit so that absolutely has something to do with it as well as e2 being in the lower range, but i love the benies i get from the hgh regardless of igf1 number,,

yeah but my current goal is to get IGF 1 as high as possible. Not so concerned about the quality of HGH I’m taking now, but I am checking serum levels anyway.

 

[25th Bam]

No , the way the glp1 work is alot more efficient at burning fat and keeping the metabolism in balance , a straight calorie deficit is only part of the bf burning,

Reta in particular increases energy expenditure on top of that. That’s why I mentioned that specifically and not just GLP 1’s in general.

 

[AlexDavis43]

I wish I learned this sooner. My first time testing IGF1 after using my first box of generics I tested 229ng/ml with my e2 crashed at 5.1. Made me panic buy a few pens of NGENLA lol. Working on getting my e2 fixed so I don’t waste any more GH

Please report back NGENLA dosing protocol and if you get IGF1 measured.

Not many data from Meso users on this.

 

[25th Bam]

Please report back NGENLA dosing protocol and if you get IGF1 measured.

Not many data from Meso users on this.

Will do . I’m pinning 22.5mgs/week split into 3 doses Mon, wed, Fri. I’ll report back here n maybe start my own thread on it. I’m new here so I gotta figure out how this works. Planning on doing bloods this week or next week. I’m hoping chase irons is right about the inaccurate IU conversion Pfizer has posted on their site.

 

[kaizoku]

Opti greys at 3iu/day put my IGF-1 at 209.
Baseline on test only was mid-160s.

 

[Juicedhead]

Here are my GH serum results from opti tropins GH, I pinned 10 units 2 hours before testing and my normal dose I’ve been on is 5 units fasted and 10 units post workout. I am dieting so I understand IGF could be a little lower.

However with previous source my IGF tested much higher at 325 so I am questioning the integrity of this GH

thats disapointing.

 

[lilhawk]

Like what

Seriously? GH has effects on various tissues and processes that aren't mediated by IGF-1. Fat metabolism being one big one.

 

[25th Bam]

Will do . I’m pinning 22.5mgs/week split into 3 doses Mon, wed, Fri. I’ll report back here n maybe start my own thread on it. I’m new here so I gotta figure out how this works. Planning on doing bloods this week or next week. I’m hoping chase irons is right about the inaccurate IU conversion Pfizer has posted on their site.

Waiting on IGF1 results. This was 8 hours after my last injection of 7.5 mg. 2nd week on Ngenla

 

[Ateam2023]

View attachment 330000
Waiting on IGF1 results. This was 8 hours after my last injection of 7.5 mg. 2nd week on Ngenla

i thought it was 9 hours after injection, on the other thread? did i miss something,,

 

[25th Bam]

i thought it was 9 hours after injection, on the other thread? did i miss something,,

9 hours is exact time. I don’t think the extra hour would make a difference with Ngenla anyway.