MESO-Rx Sponsor Opti USA DOMESTIC - HGH, INJECTABLES, TABLETS, PEPTIDES, & MISC

An update on an earlier post....
I emailed Opti when my package was later than usual. He replied 2 days later with a tracking which stated it was shipped soon after my order was placed. Mail was taking its time with it. It arrived within a few days safe and sound.
 
Hmm...well maybe degradation explains my low IGF-1 results with Opti Greys.

Jumped to 3iu in November 2024 and since then I've been reconstituting 2 vials and then combining both of those into one of the vials to pull from for injections. Lasts ~8 days.

All bloodwork results below were with Opti Greys.
Unreconstituted and reconstituted both stored in the fridge in dark containers.

Feb 2025: IGF-1 209 - Z-score 0.9 (3iu) (27.4% increase over baseline)
Oct 2024: IGF-1 195 - Z-score 0.7 (2iu) (18.9% increase over baseline)
May 2024: IGF-1 164 - Z-score 0.3 (Baseline - no HGH and no previous use)

Titrating up to 4iu now.

Do you do intermittent fasting, in a caloric deficit/low carb? Hypothyroidism or using any medications (nolva, ralox, etc) Alcohol use? These are a few things that can possibly lower liver IGF-1 response to GH per IU.


I get similar numbers to yours (Like +70ish IGF per IU of GH), but i do intermittent fasting which is proven to reduce IGF-1 as much as -50 ng/mL if i remember the numbers correctly. Also stay very lean year round.
 
Do you do intermittent fasting, in a caloric deficit/low carb? Hypothyroidism or using any medications (nolva, ralox, etc) Alcohol use? These are a few things that can possibly lower liver IGF-1 response to GH per IU.


I get similar numbers to yours (Like +70ish IGF per IU of GH), but i do intermittent fasting which is proven to reduce IGF-1 as much as -50 ng/mL if i remember the numbers correctly. Also stay very lean year round.
Appreciate the input and questions bro.

Have never been able to do intermittent fasting because for as long I can remember I've felt on the verge of starvation the moment I wake up no matter how much I eat the night before. The 1.5-2 hour wait to eat after my AM injection feels like torture.

Not in a deficit and don't eat low carb. I've actually increased my carbs since I started on HGH.

No thyroid issues or meds prior to my latest bloodwork other than telm/amlo, which I started recently.

Very little alcohol (Probably ~2 beers/drinks per week).

What's weird is that I got all the classic HGH sides (water retention, CTS, snoring, etc.) when I started and they start creeping up if I increase the dose too quickly, but the IGF-1 levels just aren't there.
 
Appreciate the input and questions bro.

Have never been able to do intermittent fasting because for as long I can remember I've felt on the verge of starvation the moment I wake up no matter how much I eat the night before. The 1.5-2 hour wait to eat after my AM injection feels like torture.

Not in a deficit and don't eat low carb. I've actually increased my carbs since I started on HGH.

No thyroid issues or meds prior to my latest bloodwork other than telm/amlo, which I started recently.

Very little alcohol (Probably ~2 beers/drinks per week).

What's weird is that I got all the classic HGH sides (water retention, CTS, snoring, etc.) when I started and they start creeping up if I increase the dose too quickly, but the IGF-1 levels just aren't there.


Your 2IU GH numbers look completely normal and your 3 IU are similar to mine.


I wouldn't worry about it because you are still responding and making IGF-1 (and there are effects and benefits of HGH that aren't even from the IGF-1 but the HGH itself, as seen in people with very low IGF-1 running tren+HGH with excellent results)


Not everyone gets +100 ng/mL per IU
 
Your 2IU GH numbers look completely normal and your 3 IU are similar to mine.


I wouldn't worry about it because you are still responding and making IGF-1 (and there are effects and benefits of HGH that aren't even from the IGF-1 but the HGH itself, as seen in people with very low IGF-1 running tren+HGH with excellent results)


Not everyone gets +100 ng/mL per IU

Oh yeah, my last cycle was test/primo/low dose tren + 3iu HGH and the results were amazing. Best cycle I’ve ever ran.

I’m not complaining, just think it’s odd that my IGF-1 is so low.
 
Your 2IU GH numbers look completely normal and your 3 IU are similar to mine.


I wouldn't worry about it because you are still responding and making IGF-1 (and there are effects and benefits of HGH that aren't even from the IGF-1 but the HGH itself, as seen in people with very low IGF-1 running tren+HGH with excellent results)


Not everyone gets +100 ng/mL per IU

If you don't mind sharing your IGF1 results on which hGH dose, I'd add it to the chart.
 
If you don't mind sharing your IGF1 results on which hGH dose, I'd add it to the chart.

289 ng/mL IGF-1 on 4 IU daily ( my last reading and multiplier i've been getting for years now)


+72.25 ng/mL IGF-1 per IU of HGH.


As far as i've seen, taking 2 IU or more shuts down endogenous production whereas <1.5 IU doses seem to add to endogenous production. (From all the labs i've seen in people running low vs higher doses)


I've been doing intermittent fasting for over a decade non-stop, so i would probably have a more normal multiplier if i was eating breakfast. (and/or higher body fat %)


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Forgive my ignorance but are the new tops on Opti's site, Gold and Light grey;
Are those the prices per kit/10 vials? Or per vial. It's a different listing format.

-Thanks Chads in advance.
 
Forgive my ignorance but are the new tops on Opti's site, Gold and Light grey;
Are those the prices per kit/10 vials? Or per vial. It's a different listing format.

-Thanks Chads in advance.
I had the same question at first, but I went ahead and ordered the Gold Tops - price is per kit (at least, I really hope so), because if it’s per vial, that’s straight-up robbery. At that point, we’re talking prices higher than Genotropin 36iu, and that would be a crime against humanity. My order should arrive in a couple of days, so I’ll update here once it’s in.
 
I had the same question at first, but I went ahead and ordered the Gold Tops - price is per kit (at least, I really hope so), because if it’s per vial, that’s straight-up robbery. At that point, we’re talking prices higher than Genotropin 36iu, and that would be a crime against humanity. My order should arrive in a couple of days, so I’ll update here once it’s in.
That was the conclusion I came to myself, and that didn't make much sense at all. So I am going with that. Wondering if the new light gray tops or old black tops are better. Difference is marginal. I'll be doing roughly 3iu a day.

Lot's of new talk about degradation on HGH. Never thought about the fillers and binders till now.

How's opti's dom shipping ?
 
289 ng/mL IGF-1 on 4 IU daily ( my last reading and multiplier i've been getting for years now)


+72.25 ng/mL IGF-1 per IU of HGH.


As far as i've seen, taking 2 IU or more shuts down endogenous production whereas <1.5 IU doses seem to add to endogenous production. (From all the labs i've seen in people running low vs higher doses)


I've been doing intermittent fasting for over a decade non-stop, so i would probably have a more normal multiplier if i was eating breakfast. (and/or higher body fat %)


View attachment 320095
What is your reconstitution/ storage method? How quickly do you go through a vial? I am guessing 2-4 days max.
 
That was the conclusion I came to myself, and that didn't make much sense at all. So I am going with that. Wondering if the new light gray tops or old black tops are better. Difference is marginal. I'll be doing roughly 3iu a day.

Lot's of new talk about degradation on HGH. Never thought about the fillers and binders till now.

How's opti's dom shipping ?
Yeah, this has been discussed a lot, and there’s plenty of useful info out there. But to make things easier, I’ve stopped overthinking it. A vial lasts me 10-12 days, and I’m fine with that. Even if some degradation happens, I doubt it’s significant by day 10-12, though I could be wrong.

As for shipping, it takes a little over a week from the moment of payment. Seems reasonable to me.
 
I go through a vail of blue tops in 5-6 days. So if I got the gold tops at 3 iu a day it would last me 10 days and apparently with all the research that’s been thrown out in this thread, it seems that 10 days is the max until degradation
 
Forgive my ignorance but are the new tops on Opti's site, Gold and Light grey;
Are those the prices per kit/10 vials? Or per vial. It's a different listing format.

-Thanks Chads in advance.

I had the same question at first, but I went ahead and ordered the Gold Tops - price is per kit (at least, I really hope so), because if it’s per vial, that’s straight-up robbery. At that point, we’re talking prices higher than Genotropin 36iu, and that would be a crime against humanity. My order should arrive in a couple of days, so I’ll update here once it’s in.


The price is per iu.
 
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