Outline Proviron

cathex said:
Can anyone outline the uses of proviron. Can it be used for pct etc?

You should never use proviron (mesterolone) for pct. Proviron is a 1-methylated form of DHT, which is quite suppressive.

Because it has a high affinity for the aromatase enzyme, it helps to reduce the conversion of test to estrogen. This reduction in estrogen also means fewer gyno and water retention problems, resulting in a harder look when using Test or Dbol. To get this effect, you need about 100mg's+/day. Personally, I saw no benefit at 50mg's/day, although others might.

True aromatase inhibitors such as arimidex or letrozole do the same job much better than proviron. Because it's superficial effects are similar to something like nolvadex or clomid, it's possible some people have thought it could be used like them for pct. As DHT, it can fill the role of a replacement for Test and using it for pct and the resulting increases in libido may give some people the incorrect impression that their own natural Test had kicked back in. That's a big mistake.

Without going into all the details, some information suggests mesterolone increases the potentcy of exogenously adminstered Test. By binding to the SHBG and albumin, it leaves more Test to circulate unbound. This would not apply to natural test as the test levels are too low to make a difference. Don't take proviron by itself, there's zero benefit in that case and it will suppress your natural test levels.

So the decrease in estrogen, resulting harder look, increased potentcy of Test and increased libido are the reasons for using proviron. In the real world, all of these effects are subtle. If you have the extra money, it doesn't hurt to include it in your cycle. If you don't have the extra money, don't worry about it, you're not missing much.

MaxRep
 
Excellent info and overview by MR. Just one thing to add...
Since proviron is a very androgenic compound, in addition to "occupying" SHBG or albumin so as to free up more bioavailable AAS. it also actually lower SHBG levels by two means...
a) by serving as an AI, it reduces estrogen. Estrogen has been shown to increase SHBG levels
b) by simply being an androgen. Increasing androgens has been shown to reduce SHBG levels...the mechanism isn't clear, but the trend is very clear.

Just to reiterate what MR said, it should NOT be used during pct, as it will suppress HPTA. People have argued that it's not AS suppressive as other compounds....who cares?! It's suppressive, and that's counterproductive to your primary goal at hand during pct.
 
I like to throw proviron in for the last 3 weeks of my cycle. Since it lowers SHBG, I figure it might help recovery when I come off and start PCT, if the lowered SHBG effect holds over for a week or two. Don't know if this actually works, but I figure it can't hurt.
 
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