That's an important distinction JI. Although somed PEPs may prove effective in relieving discomfort on an individual basis their MOA is unknown and unproven.
That's to say do PEPs actually HEAL DAMAGED CARTILAGE, ligaments or tendons or do they simply diminish the inflammatory response.
To date the evidence reveals the healing of intra-articular structures can only be promoted when they are directly exposed to specific growth factors, such as IGF, fibroblast inhibitors and primordial cellular agents as in stem cells.
Understand this is a staged process in which these agents are instilled directly into the joint in s time specific manner.
Unfortunately there is NO EVIDENCE the parenteral administration of either PEPs, GH or even IGF are capable of HEALING cartilage or those stromal components common to tendons or ligaments.
That's to say do PEPs actually HEAL DAMAGED CARTILAGE, ligaments or tendons or do they simply diminish the inflammatory response.
To date the evidence reveals the healing of intra-articular structures can only be promoted when they are directly exposed to specific growth factors, such as IGF, fibroblast inhibitors and primordial cellular agents as in stem cells.
Understand this is a staged process in which these agents are instilled directly into the joint in s time specific manner.
Unfortunately there is NO EVIDENCE the parenteral administration of either PEPs, GH or even IGF are capable of HEALING cartilage or those stromal components common to tendons or ligaments.
