Peptides that can be mixed together

[FrogMan]

I came across this compatibility chart of what Peptides can be mixed together. (Take with the biggest grain of salt)

It's common for vendors and clinics to sell mixed peptide solutions such BPC+TB500, CJC+IPA, etc. However, I'm assuming these are all sent to Janoshik in their lyophilized form and not given significant time to show the degradation that can happen from mixing products once reconstituted and sitting in your fridge for 3 weeks.

Jano is not able to test purity of combination peptide vials, only the mg quantity.

So, I'm wondering if you can take a reconstituted batch of pre-tested Peptide 1 + Peptide 2, mix together, send to jano, and if it comes back as the proper mg for each you're good? Or is there more to it?

Also, is this chart total bullshit? I'm assuming there's more to it that would mean a standardized chart of "this peptide combines with this peptide" would leave out variables such as different excipients that vary across sources causing interactions.

What do you guys think? Is it possible to actually have an archive of peptide combos?

 

[IndividualMan]

leave out variables such as different excipients that vary across sources causing interactions.

yes, but having a reference sheet can be helpful

 

[Prze1]

I wouldn't mix a GLP with anything. It's only a once a week pin so no big deal

 

[ostrichsak]

There's actual documented test results out there from Jano of exactly what you're talking about.

They took some Klow-80* from the same batch and reconstituted it, tested samples immediately and then tested again 28 days later. The degradation was less than 3% between the two test groups, if I recall. Basically statistically insignificant especially when you consider fills can be over or under 10% or more commonly.

This idea that peptides degrade if stacked is silly. I saw a YT video by "doctor" Travis Bachmeyer (aka disgraced Crossfit cheater & known scam artist) where he claimed that doing this was bad because of how it impacted pH levels. Uh... wut? That's not how any of that works.

Bacteriostatic water is 5.7pH ish. The proper range for storage of peptides is between 5-6 (this window increases pretty dramatically if administering immediately but not important here). The suspension (BAC water) makes up like 99% of your reconstituted peptide by volume. If you think that something with the mass weight of a few dozen milligrams is going to have ANY effect on mean pH, I've got some swamp land in FL I'll make you a real good deal on.

Just goes to show you that you can say some pretty dumb shit but if you say it convincingly enough lots of people will believe it.

*(Klow-80: stack of 4 peptides: GHK-Cu, BPC-157, TB-500 & KPV for those who aren't aware)

 

[FrogMan]

There's actual documented test results out there from Jano of exactly what you're talking about.

They took some Klow-80* from the same batch and reconstituted it, tested samples immediately and then tested again 28 days later. The degradation was less than 3% between the two test groups, if I recall. Basically statistically insignificant especially when you consider fills can be over or under 10% or more commonly.

This idea that peptides degrade if stacked is silly. I saw a YT video by "doctor" Travis Bachmeyer (aka disgraced Crossfit cheater & known scam artist) where he claimed that doing this was bad because of how it impacted pH levels. Uh... wut? That's not how any of that works.

Bacteriostatic water is 5.7pH ish. The proper range for storage of peptides is between 5-6 (this window increases pretty dramatically if administering immediately but not important here). The suspension (BAC water) makes up like 99% of your reconstituted peptide by volume. If you think that something with the mass weight of a few dozen milligrams is going to have ANY effect on mean pH, I've got some swamp land in FL I'll make you a real good deal on.

Just goes to show you that you can say some pretty dumb shit but if you say it convincingly enough lots of people will believe it.

*(Klow-80: stack of 4 peptides: GHK-Cu, BPC-157, TB-500 & KPV for those who aren't aware)

I wasn't aware of that test. Good to know.

So we're not aware of any tests that actually showed degradation of any peptides that can't mix together?

For example, people like it's common knowledge that glp1's can't mix with anything. It's even shown in that chart i posted. I'm just curious if there's any history of people performing and finding combinations that can't work. (Not just glps)

It's commonly spouted by youtubers saying it's a bad idea. I've heard Big Paul and Vigourousteve say the same. So I'm wondering where the actual evidence for this could be lol

 

[IndividualMan]

Insulin+ GH seems to be bad, but htats probably also excipient related

 

[AcieSlater]

Here's what ostrichsak references in case youre curious: Debunking the Myth That Mixing GHK-Cu With Other Peptides Causes Damage - Xcel Peptides

The problem with nearly all peptides is that there's virtually no scientific basis to support any claims, much less any information on combining them.

The KLOW blend is a good example. There is no human evidence on KPV. There is no human evidence on GHK-cu (injections). There is scant human evidence on bpc-157 and the evidence that exists is weak. TB-500 has been researched and the evidence does not support the purpose for which it is being marketed.

Bachmeyer and others peddling these peptides cite rat and in-vitro studies like they are fact, but the reality is that no one actually knows if they do anything when introduced exogenously.

The placebo effect is strong in this market because no one wants to hear that spending a ton of money and stabbing yourself is all for nothing.