Pitavastatin+Bempedoic acid+Ezetimbe really works well.

Yes sir - just used it earlier today!

I have a stupid question, maybe @Ghoul can chime in.

One of the criticisms I hear, but do not agree with, is that simply chasing LDL numbers is not helpful, and that outcomes data is where it's at. Now I think that's true and not true, and way too nuanced to dive into. But my question is this...

If we have 3 distinct classes of drugs (statins, zetia, Nexletol) that all lower LDL independently, and all have positive outcomes data associated with them, is there any way that using them altogether would not have a synergistic impact on outcomes? Meaning that is there any manner in which combining pitavastatin, Zetia, and Nexletol, which we know will lower LDL significantly in combination, somehow does not lead to better outcomes data than just using one, or two of them alone?

I'm also still hearing some ( a lot ) of pushback from docs of various specialties regarding the "don't drop your LDL too low" mantra of yesteryear. I know this paper is only 18 months old, but it is a potential paradigm shift in how lipids are managed, and not a single doc I've spoken with was 1) aware of it, and 2) thought it was compelling.


@Ghoul is there ANY reason to "not let your LDL go too low"?
 
Yes sir - just used it earlier today!

Works for Nexlizet too.
Bemp + Eze combo.

$25/90d.
Quite easy to get a 1 year rx from a doc.


I think you have mentioned before but what's the persons reship policy?

Most IndiaMart vendors don't reship, but given how much you save vs the other vendors here, you can easily afford a few seizures. They use the same shipping routes.
 
For anyone who needs it, and you’re more of a 500-1000 at a time stock up type, my Indian wholesaler has

Pivasta 4mg x 1000 $420 (Zydus Pita, same as US Zypitamag). That’s $38/90, better than costplusdrugs $50)

PTVS DUO 4/10 x 1000 $425 (Pita 4/Eze 10 combo)

Zetiheal 10mg x 1000 $96

Etc.

DM if you want his info. As long as you’re buying by the box (usually 100 tabs) no one is cheaper than him and he can get anything available (I mean normal pharma, including TRT, but not the sketchy controlled pain meds etc).
Id send u a message but u never respond… like the last couple messages i sentcha
 
Pita 4 x 90 is $55 delivered from costplusdrugs , close to India prices, as another option.

Of course Repatha is the holy grail. If you can fake statin intolerance to get that (with the copay card from Repatha.com it’s only $25 / for 3 months), then you can add Pitavastatin + eze back in (they won’t take Repatha away once approved) for the ultimate lipid stack.

surprised repatha hasn’t “leaked” onto the supply chain yet -
Recent lab work:

View attachment 361982

The March 25 labs are pre-cycle. The Oct 25 labs are 5 week into a cycle of 400mg Test, 300mg Deca, 400mg Mast per week with a bit of Dbol thrown in for good measure.

The Nov 25 labs are 4 weeks later with 600mg Test, 450mg Deca, 400mg Mast per week with a bit of Anadrol tossed in. The difference is immediately after the Oct lab I started: Pitavastatin 2mg eod, Ezetimbe 5mg eod, Bempedoic Acid 90mg eod. Half pills and every other day dosing still dropped it this much.

After the Nov labs I've changed to daily dosing, but still half pills. Can't wait to see what happens for the Dec labs.

very high IQ lipid stack - congrats on the results!
 
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