Propionate vs Enanthate

Vash1986

New Member
Hi guys :)
Today I will bring you my personal experience with TRT.

I am 25, poor libido, and I've had multiple labs that showed Total Testosterone below 400 ng/dL (throughout a year i had 470, 330, 450, 370, 320).

Free testosterone dropped under the range just twice, once last year and once this year. Last year I had testosterone cream, this year I had testosterone injections.

I wanted to share my experience because it's quite interesting. I know that in the US testosterone cypionate is used for TRT in 90% of the cases.

Here in Italy, doctors prescibe either enanthate (almost the same as cypionate) or propionate.

My doc gave me 125mg Testoviron (enanthate) once a week. Labwork showed a test level of 1060ng/dL (range 270-900) in the middle day of the week. Crappy libido. Enough to get an erection but never to have real desire.

Then we switched to 50mg Testovis (propionate) every 4 days. Total test was to 790ng/dL 60hours after an injection. Great libido, with highs and lows. Some days it was so raging I couldn't even kiss my girlfriend without getting a hard one. Some other days I have some problems in maintaining an erection, but achieving is no prob.

Actually, before switching to proionate, I also tried 80mg enanthate once a week. It didn't work either. So here are my personal conclusions:

1) I am almost sure that every person has his optimal level of testosterone, and having more not only will not help, IT WILL MAKE YOU WORSE.

2) Even if you achieve an optimal level, remember that we have a circadian rythm with very large variations. In the average healthy young male test levels go from 350 (evening) and 700 (morning). This suggests that having a permanently high testosterone level is no use. Many bodybuilders on cycle or people on high dose TRT have no libido after the first weeks/months. Why on earth should this happen? There are two explanations: high estradiol and brain androgen recepter desensitization.

So these two considerations bring us to the following conclusions:

a) Dont' exeed your optimal level
b) Have frequent fluctuations in your test levels

Of course, there is no scientifical evidence that a fluctuation in test levels is strictly necessary. But consider this: you will never precisely know what your optimum level is. It could be 550. It could be 700. It could even be 800 or 400.

So let's say experience after months of TRT tells you that your libido is best around 600ng/dL. So what's your optimum level? 550? 580? 620? What if you manage to have a stable level of 630ng/dL with every 3 days shots? It could be too much if your optimum is 580.

So the best thing you could do, in my opinion, is to have the test level fluctuate from 400 to 800.

Let's see what happens with test enanthate. Having 200mg every two weeks just makes no sense. You get too high levels and then you go way too low.

Having 100mg once a week makes you absorb approx these quantities of test starting from week no. 5:
day 1: 20
day 2: 17
day 3: 15
day 4: 13
day 5: 11
day 6: 10
day 7: 9

The first 3 days you get more test than you need, so the level raises, probably almost suvraphysiological. The fourth day you stay stable. Then the level goes down to mid-low levels (but within normal range) at day 7.

What does this mean? It means you will have TOO MUCH testosterone for 4 days a week. Your receptors will desensitize and when your test level is normal (days 5,6,7), you won't be sufficiently stimulated to have a good libido.

So that's why many people do 3 injections per week. They keep a steady state level, constantly for all the week.

But what if it is a bit too low? Crappy libido. What if it is a bit too high? Crappy libido ANYWAY!!! And what if we really need a fluctuation to have good libido?

So here is where test propionate comes in. It has a 2 days half life. Meaning that dosing shots every 3 days at 50mg will give you:
day 1: 21
day 2: 15
day 3: 11

So let's see what happens: you get a high dose of test just one day. Your test level goes up, but not suvraphysiological. It just gets high, and quickly (raging libido). Then it remains stable (good libido). Then it goes down, but remains in the normal-low range (mediocre libido). Being normal and then a bit low, the receptors are more sensitive to the next dose, thus giving you again raging libido with the next shot.

Of course, every person is different, and what worked for me may not work for others. But I strongly suggest you try propionate if having poor results with cypionate. And don't exceed the dose. Perhaps you could even run it every 4 days if you have good SHBG (mid-low).
 
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I have the same reaction to propionate. The doctor may make fun of you, but the truth of the matter is that the propionate ester releases the testosterone very fast. This elevates free testosterone and makes you feel better. When I take enanthate, unless my SHBG is very low and estrogen is low I feel like shit. Propionate in my body at least does not convert to estrogen nearly as to what enanthate does. I need double the AI dose on enanthate vs propionate.

150 mg of propionate is more stimulating to me than 4 times that dose of enanthate or cypionate.


Especially if your body has a slight problem in energy metabolism or excessive estrogen conversion, the increased speed of release will definitely be more noticeable. Some things it just takes experience to believe.
 
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Oh really? It's nice to hear this from someone else.

I suspected that test prop for some strange reason aromatized less than enanthate, because I get water retention on enanthate and instead I get some acne on proprionate!

It's just sad there's no sensitive estradiol test in my town, so I will never get the correct dose of AI (in fact, i don't use it at all....)

How much propionate do you take? It's just 50mg every 4 days for me. But I'm 1.72m @ 65kg.
 
My .02 worth, Prop definitely jacks my libido. When I cycled I loved prop. Now at age 50 on an TRT w Cyp, at about 125 MGS a week in 3 shots per week its definitely not there, if I rasie my CYP to 300 mgs a week I get a little boost that fades fairly quickly. I just roll with it.
 
I can't tolerate enanthate. I get really mean on it. I'm assuming this is from a higher estrogen conversion. When the enanthate goes out of my system I will piss out several pounds of water just from the estrogen stress. And I do take letrozole and whatnot on it. I have to take double the aI dose on enanthate compared to propionate as I may have said before. Overall I'm just not a fan.
 
Lol the same thing happened to me. When I went from enanthate to prop i pissed quite a lot, one of the last days before the prop shot (and lost 1kg)
 
Without commenting on the bulk of what's written I'll volunteer that a significant number of people on HRT seem to like prop over enanth or cyp. Likely this is due to speed of release and lower estrogen conversion.

Only negative is that some don't tolerate prop well and get injection pain and test flu symptoms.
 
The only idea I have is that the testosterone is biologically active in the system for a shorter time, causing less ability to aromatize. Natural testosterone is pulsed every 15 seconds. I'm not sure if an enanthate ester for example would entirely remain unrecognized in the body while attached to its ester or not. It must, because water retention and symptoms of high e2 are known amongst everyone trying different esters.
 
But even if the time is shorter, prioponate has a higher peak. And aromatization should be stronger in such case.

Anyway... that's just theory. One must do what makes you feel well. I feel better on prioponate, so perhaps it's useless to do this brainstorming, but still interesting :)
 
I just think a fast release of testosterone is akin to crack cocaine. I mean it is stimulating to the body...to the neurotransmitters. No doubt dopamine is elevated more on a faster release of testosterone.
 
The only idea I have is that the testosterone is biologically active in the system for a shorter time, causing less ability to aromatize. Natural testosterone is pulsed every 15 seconds. I'm not sure if an enanthate ester for example would entirely remain unrecognized in the body while attached to its ester or not. It must, because water retention and symptoms of high e2 are known amongst everyone trying different esters.

Every 15 seconds? More like every 2 hours.
 
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