Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[WhyteOwl]

Truly, I don’t think it matters in the least. It’s a SubQ injection that takes many hours to reach its peak. It has a 5-6 day half-life. I’ve read literally thousands of reports from users, and never seen a single one that has the issues this dude is talking about. HGH users have never seen an issue either. There is a guy from Discord that got ran out of all the servers because he kept spreading “fake science”, and this sounds very similar to that dude.

Which flavoring for the liquid antibiotics works best for my kid's strep throat? I usually get bubblegum by default, but I think cherry might treat it faster.

Sarcasm above, BTW. Get the med in, try not to get any ISR. Accomplish that and you're good. I enjoyed reading what ghoul had to say up until today. I'd love to know what made him write this twice today.

 

[Juiced_lizard]

I got 36iu (40iu in QSC) in 1ml of BAC. Take 2iu (5 units) before working out. 5 units before bed. Seems to work fine for me.

I also do 1ml for a 36iu (40) from QSC. Works just fine for me. I’ve done 1ml for 15 iu also. 10 iu I’ll use .5ml.

 

[Middus]

I have been looking around for solid information on correct reconstitution ratios for Retatrutide and Tirzepetide but i cannot seem to find anything. Can you enlighten me please on what you have found?

I beseech thee to wasteth thine time not.. lol. These things existeth not in Beth-PeerReview, even yonder.

 

[Middus]

Truly, I don’t think it matters in the least. It’s a SubQ injection that takes many hours to reach its peak. It has a 5-6 day half-life. I’ve read literally thousands of reports from users, and never seen a single one that has the issues this dude is talking about. HGH users have never seen an issue either. There is a guy from Discord that got ran out of all the servers because he kept spreading “fake science”, and this sounds very similar to that dude.

Don't worry, definitely not the same person. Said individual would have a tough time with the crowd here. There will be little tolerance both ways.

 

[JimmyJack]

Why the difference in pill shape for the 5amino I got round brown and my buddy got oblong shaped?

 

[Trenbolonetax]

Why the difference in pill shape for the 5amino I got round brown and my buddy got oblong shaped?

You probably got the rat poison

 

[Ghoul]

This is the second time I've seen say this here. Can you enlighten us on how they should be diluted? I haven't seen any data on this before. Thanks.

Please don't take anything in this response personally, it's a reasonable question.

I use it to illustrate the absurdity of how the most basic factors don't cross the mind of people using these compounds, who are so confident making up protocols based on "feels", mixed peptide recipes, and scoff at what's taken massive amounts of effort to ensure is a safe, effective protocol.

Other factors like dosing frequency are equally significant, but this is the simplest to explain.

Reconstitution ratios affect two major factors:

First, the amount of liquid determines the pharmacokinetics, ie how quickly the dose is delivered systemically. The more liquid, the slower the rate of delivery. Cut that dose of Sema from .75ml to. .10ml, and instead of building in blood levels slowly over several hours, it'll be minutes. This intense hit of Sema can significantly increase the strength of side effects and induce transient hypoglycemia (low blood sugar).

Secondly, the more concentrated the solution is, the higher the rate of "aggregation". Aggregates are formed from peptides "sticking" together, and TLDR, they become ineffective and wasted. This gets progressively worse with time, reducing potency.

Immune response is also impacted by concentration, but too much to get into here.

For the "correct" concentrations, refer to what pharma uses. If not an approved drug, refer to the clinical trials. Finally, if it's not a pharma compound, look at what researchers are using in their studies. It tends to be uniform.

Exceeding the "correct" dilution rates isn't a significant problem, the worst impact slowing the amount of time needed to take effect. Going lower causes the problems above and should be avoided.

So, as examples:

Sema: Up to 1.4mg, .50ml per dose.
then Up to 2.4mg, .75ml per dose

Tirz: Up to 15mg, .50ml per dose

Reta: Up to 12mg, .50ml per dose

PT-141: Up to 1.75mg, .30ml per dose

HGH: No less than .05ml per iu.

 

[Grey Spartan]

Trust me I would. Just don’t want to totally fry my spermies

Sissy

 

[Docsunshine23]

This poor people shopping promo stuff always confuses. How much would shipping run on 6-8 kits of HGH from promo?

 

[Spaceman Spiff]

Please don't take anything in this response personally, it's a reasonable question.

I use it to illustrate the absurdity of how the most basic factors don't cross the mind of people using these compounds, who are so confident making up protocols based on "feels", mixed peptide recipes, and scoff at what's taken massive amounts of effort to ensure is a safe, effective protocol.

Other factors like dosing frequency are equally significant, but this is the simplest to explain.

Reconstitution ratios affect two major factors:

First, the amount of liquid determines the pharmacokinetics, ie how quickly the dose is delivered systemically. The more liquid, the slower the rate of delivery. Cut that dose of Sema from .75ml to. .10ml, and instead of building in blood levels slowly over several hours, it'll be minutes. This intense hit of Sema can significantly increase the strength of side effects and induce transient hypoglycemia (low blood sugar).

Secondly, the more concentrated the solution is, the higher the rate of "aggregation". Aggregates are formed from peptides "sticking" together, and TLDR, they become ineffective and wasted. This gets progressively worse with time, reducing potency.

Immune response is also impacted by concentration, but too much to get into here.

For the "correct" concentrations, refer to what pharma uses. If not an approved drug, refer to the clinical trials. Finally, if it's not a pharma compound, look at what researchers are using in their studies. It tends to be uniform.

Exceeding the "correct" dilution rates isn't a significant problem, the worst impact slowing the amount of time needed to take effect. Going lower causes the problems above and should be avoided.

So, as examples:

Sema: Up to 1.4mg, .50ml per dose.
then Up to 2.4mg, .75ml per dose

Tirz: Up to 15mg, .50ml per dose

Reta: Up to 12mg, .50ml per dose

PT-141: Up to 1.75mg, .30ml per dose

HGH: No less than .05ml per iu.

You are suggesting the concentration of the drug being delivered is affecting the time of effect? Lol


This honestly sounds extremely ridiculous. Especially for hgh.

What evidence is there to support this statement?

Or even for tirzepatide? Is it just as simple as "the auto injectors are just loaded with 0.5ml?".

 

[Clover 0080]

Got a quick question for you Triz users. Have never used a GLP-1 as I usually am pretty good with my diet nowadays. However I am interested in some of the benefits I have been hearing about besides weight loss. I have tried every other compound under the sun, so why not.

Quick question is, did you start off with the pharma recommended dose of 2.5mg/week for 4 weeks before going to 5mg and possibly all the way up to 15 if needed, or did you just start off with the 5 or higher, or lower than 2.5 for that matter.

started with 5 immediately but it was pharma grade bought off someone else not written by my personal dr. But I've heard of drs actually starting people on 5 right from the jump too

 

[kmh1234]

Has anyone had issues with there raws being marked incorrectly? The marked numbers are not matching the serial numbers on my order. I know what tren and EQ looks like and there marked with different numbers then my order shows.. I know there are others marked incorrectly by the weights. My first time ordering from these guys so not sure if I’m looking for the wrong numbers

 

[AlexDavis43]

Finding the lowest possible amount of BAC that will dilute the peptide is less likely to be a better answer than going in the other direction.

For example, yes it will dissolve in 0.6 mL but you can easily fit 2 mL in the vial. Put 2 mL in the vial unless there is a specific indication to use less.

It's still a very low injection volume, if that's what you're worried about.

 

[BP_6]

Has anyone had issues with there raws being marked incorrectly? The marked numbers are not matching the serial numbers on my order. I know what tren and EQ looks like and there marked with different numbers then my order shows.. I know there are others marked incorrectly by the weights. My first time ordering from these guys so not sure if I’m looking for the wrong numbers

I know it is like this with the recent int vials. Despite what the serial number shows on the email with your order, email the rep who did your order and they will give you the real numbers.

 

[AlexDavis43]

What's the minimum dilution for HGH ?

Curious on this cuz I dilute any vial less than 16iu with .5ml and shoot it all

That's pretty concentrated. I do mine the opposite with more dilution. For example on a 36iu vial I use 3cc of water. Which gives 1/2 a cc as 6iu. Didn't even think about it possibly mattering.

There isn't great science on this but for 10 IU vials, I add 2 mL BAC and shoot it in two 1 mL subQ shots daily.

In the absence of better evidence, I'm siding with more diluted rather than more concentrated (for other peptides too).

 

[Dirthand]

Has anyone had issues with there raws being marked incorrectly? The marked numbers are not matching the serial numbers on my order. I know what tren and EQ looks like and there marked with different numbers then my order shows.. I know there are others marked incorrectly by the weights. My first time ordering from these guys so not sure if I’m looking for the wrong numbers

I had problem with an order i got yesterday.. email tracy..

 

[readalot]

Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics - PMC

The importance of drug dosing time in pharmacokinetics, pharmacodynamics, and toxicity is receiving increasing attention from the scientific community. In spite of mounting evidence that circadian oscillations affect drug absorption, distribution, ...

pmc.ncbi.nlm.nih.gov

chronopharmacokinetics for more fun.

 

[Trenbolonetax]

Sissy

Don’t make me fuck around and find out.

 

[AlexDavis43]

Timing in drug absorption and disposition: The past, present, and future of chronopharmacokinetics - PMC

The importance of drug dosing time in pharmacokinetics, pharmacodynamics, and toxicity is receiving increasing attention from the scientific community. In spite of mounting evidence that circadian oscillations affect drug absorption, distribution, ...

pmc.ncbi.nlm.nih.gov

chronopharmacokinetics for more fun.

PTSD from one of my postdocs for sure.

 

[thecmorgan]

Got a quick question for you Triz users. Have never used a GLP-1 as I usually am pretty good with my diet nowadays. However I am interested in some of the benefits I have been hearing about besides weight loss. I have tried every other compound under the sun, so why not.

Quick question is, did you start off with the pharma recommended dose of 2.5mg/week for 4 weeks before going to 5mg and possibly all the way up to 15 if needed, or did you just start off with the 5 or higher, or lower than 2.5 for that matter.

I started at 1250mcg and upped it 1250 every 4 weeks