Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[MyNameIsJeff]

No, oil, heat and solvents do.

Tren A is what turns dark with bad purity that is oxidized, the hotter it gets the darker as well.

Oxidation don't happen after a brewed batch, it's in the raws or someone got the vial so hot it had steam in it that you can't see unless the top is taken off.

Steam is moisture, moisture causes oxidation.

The reason tren a use to be crap purity until testing come popular, is it was left with too much moisture as water is used as a finally process. The water wasn't dried enough.

Year back source brewed in water on stove tops, that caused issues as well.

Hopefully one of our resident brewers can chime in on this.

 

[eggrollfever]

Maybe my experience has been an anomaly, but I’ve had zero communication issues with QSC over several years of orders. I don’t know the reps’ names and I honestly can’t fathom what could happen that would result in me learning them. This is the entire thread for a single order:

Me: Hi, international.

3x Product 1
2x Product 2

Name
Address

USDC

QSC: payment address

Me: hash

5-7 days later Me: is tracking available?

QSC: tracking number


That’s all it takes, no more, no less. If the tracking updates stop I’ll wait 30 days and request reshipment, maybe place a domestic order in the meantime if I’m running low.

 

[salladen]

Maybe my experience has been an anomaly, but I’ve had zero communication issues with QSC over several years of orders. I don’t know the reps’ names and I honestly can’t fathom what could happen that would result in me learning them. This is the entire thread for a single order:

Me: Hi, international.

3x Product 1
2x Product 2

Name
Address

USDC

QSC: payment address

Me: hash

5-7 days later Me: is tracking available?

QSC: tracking number


That’s all it takes, no more, no less. If the tracking updates stop I’ll wait 30 days and request reshipment, maybe place a domestic order in the meantime if I’m running low.

After you have recived your tracking number, how long does it take for them to start shipping? I got tracking 2 weeks ago, still "Your package is waiting to be picked up by the carrier."

 

[gixxiepoo]

I've ordered with QSC many times over the years with no issue until now.

So I placed an order for 500g of testE raws during last month's promo. I was sent 20 vials of oils. Thru emails I learn these are testE vials, and now they want me to pay to send these to some random person before they ship my raws? Wtf.

I've now been told that the rep that messed up my order is no longer employed. Emails leading up til now from QSC have lacked explanation on the situation, but I will be trying to sort this out. The address given was not a customer.

 

[eggrollfever]

After you have recived your tracking number, how long does it take for them to start shipping? I got tracking 2 weeks ago, still "Your package is waiting to be picked up by the carrier."

Where are you tracking it? I use parcelsapp.com and the first status is usually a scan at an airport in China.

 

[Grey Spartan]

I've now been told that the rep that messed up my order is no longer employed. Emails leading up til now from QSC have lacked explanation on the situation, but I will be trying to sort this out. The address given was not a customer.

Good job on the follow up. Good to hear a customer wasn't doxed. Hope everything works out for you brother.

 

[Ghoul]

So hypothetically if someone wanted to take a "little break" for whatever reason say they were at goal weight or they were pinning something else and didn't want the interaction...it takes about 30 days to completely clear any tirzepetide/semaglutide from your system. After this point is when the body starts to make "memory T cells" right? It would be more beneficial to stay on a low maintenance dose just to make sure its never cleared from your body (if you have intentions of ever getting back on a glp1)
As long as someone keeps a low dose in their body stretched no longer then 30 days between injections that will help prevent this future reaction. I'm sure tons of people stop GLP-1s all together thinking they will never need them again and then oopsy gained all that weight back and now its going to be a lot more difficult to lose it.
That is considering they can afford the long-term low maintenance dose especially if they are paying out of pocket for pharma grade.

So unfortunately we're dealing with a lot of unknowns, largely because peptide pharmaceutical development is all about finding a formula, manufacturing method, and treatment plan that avoids immunogenicity problems, long before the first human trials begin.

The best we can do is draw conclusions from drugs that, despite appearing to have no immunogenicity issues, end up having them once patients have been using them for a while, and there are numerous examples, including GLP class pharmaceuticals.

The problem of "reexposure immunogenicity" has been dealt with successfully by maintaining a small dose, That suggests that as long as there's some level of the drug present, "memory t-cells" don't become a problem.

So 5 half lives are needed for complete elimination after the last dose.

35 days for Sema
25 days for Tirz

But that's on average. Some people will rid themselves more quickly, and it's been suggested UGL copies also have a shorter half life.

Without specifically studying a particular compound, no one knows how much time after complete elimination it takes this "reexposure immunogenicity" to develop. But the longer the gap the worse the risk.

So the best strategy would be to stay on a small dose rather than stop entirely.

Next best would be not letting more than the time above elapse before getting back on.

Finally, keeping the gap in treatment as short as possible would he better than allowing a long gap.

No guarantees with any of this, but based on what's known, this is the way to minimize the potential of reexposure immunogenicity.

https://pfizermedical.pfizerpro.com/api/vc/en/medical/assets/7f63126f-66e6-4979-9da0-2f3438b1814f/PMP%20Biosimplify%20Interactive%20Infographic_Biosimilars%20and%20Immunogenicity.pdf

https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-immunogenicity-assessment-therapeutic-proteins-revision-1_en.pdf

 

[flipup7]

Great to see the new enhanced testing results from QSC a week or two back. Given that and the fair point about people only ever posting their problems just wanted to post my QSC experience:

I recently completed another successful order with QSC. I've had some minor comms issues and one packaging/labeling issue in the past, but they were resolved with a little bit of patience. I've always gotten exactly what I ordered, for the price I was quoted.

I know Tracy isn't exactly known for giving the warm and fuzzies but I'd rather a little sand paper and good results than smiles and scams. Especially given the recent activity about other vendors and "0 peptide" issues on the soccer mom forums.

Good on the community here for pushing for better testing and logisitics and good on QSC for responding. There's a healthy tension between customers and QSC here, it can look ugly but it's exactly what this market needs to function well.

 

[Luka.Halotestin]

Maybe my experience has been an anomaly, but I’ve had zero communication issues with QSC over several years of orders. I don’t know the reps’ names and I honestly can’t fathom what could happen that would result in me learning them. This is the entire thread for a single order:

Me: Hi, international.

3x Product 1
2x Product 2

Name
Address

USDC

QSC: payment address

Me: hash

5-7 days later Me: is tracking available?

QSC: tracking number


That’s all it takes, no more, no less. If the tracking updates stop I’ll wait 30 days and request reshipment, maybe place a domestic order in the meantime if I’m running low.

Same here. I figured out Tracy isn't a "warm" type of supllier so I use the least amount of words possible to communicate and have zero problems. I just hit her up with my order and address, send hash when I pay and ask for tracking code few days after.

Zero problems with shipping so far. The only problem I had is she used my real number instead of a fake one in my first two orders. I told her at my third order to use my fake number because I might get into trouble for it and she did use a fake number from then on.

I suggest everyone to keep their messages brief with her and only use one way of communication. Do not spam and I think you will be just fine.

 

[narta]

Hopefully one of our resident brewers can chime in on this.

Here.

lol at the explanation.

Tren turns dark orange because of heat, so Test E. No degradation takes place, there are plenty of tested Test E and Tren E/A with varying colors that tested at the target concentration. I have personally brewed Tren E/A from slightly yellowish to dark orange with no difference in target concentration confirmed by HPLC. Same for Test E.

Moisture produces foggy liquid.

Color of raws are dependent to purity and batch production parameters (purity of chemicals/intermediates used)

 

[narta]

View attachment 310130lol even with tren H labels, customs opening it and all that ...they still landed today. Still waiting for some GH and peps stuck in customs

Clean house and go buy some lube.

 

[Ghoul]

View attachment 310130lol even with tren H labels, customs opening it and all that ...they still landed today. Still waiting for some GH and peps stuck in customs

Damn close call. You must've been shitting bricks lol

 

[Grey Spartan]

View attachment 310130lol even with tren H labels, customs opening it and all that ...they still landed today. Still waiting for some GH and peps stuck in customs

No random bottles of Anavar or tracking devices?

 

[AlmightyAlpha]

Clean house and go buy some lube.

No need lol

 

[narta]

No need lol

For house cleaning or lube? lol

 

[AlmightyAlpha]

For house cleaning or lube? lol

Lol neither you hoe lol

 

[AlmightyAlpha]

No random bottles of Anavar or tracking devices?

I wish they'd throw in random free var

 

[juicedtothagillz]

I've been breaking them in half. The NAD tabs are the same size (I have both NAD and UDCA)
But yeah, even broken in half, it gets caught and doesn't go down the throat sometimes.

I'm chewing these UDCA like food

 

[Grey Spartan]

I wish they'd throw in random free var

Strange, other people who have had their packages checked by customs had Anavar placed in their packages from a different company. I think they did order Anavar from QSC though.

 

[mok4315]

So the whole reason this guy is so off base is because we have people like you running defense and doing customer support for this source like they are special. Youre literally handling customer issues and providing an email like theyve deserved this special treatment. holy fuck.
you think you are helping but you prop this source up

they could easily have more people managing emails for quicker response times, hire better english speakers, have a better system in place for ordering that prevents this from happening in the first place, have a rep in this thread handling concerns (a visible one) but instead, they dont have to, they have you clueless people to soften up or victim blame every complaint and act like its all fine

let the source stand on their own two fucking feet.

I kind of doubt *I* am the reason QSC does what it does, but if you want to believe I have that type of power, I certainly won’t stop you. Go me.