Qingdao Sigma Chemical Co., Ltd (International, US, EU, Canada and Australia domestic

[LGOP528]

Make sure you get a satisfying answer you can verify, or quietly seek a second opinion if you're told you're an unsuitable candidate.

You're only a boat payment to most surgeons.

Will do. I am getting an mri soon so I will know a little more. Here is my old mri from 3 years ago.

 

[Ghoul]

Prions are terrifying. If I understand correctly they are basically indestructible. If they get into lab, surgery, pharmaceutical, etc. equipment I believe everything has to be destroyed as it cannot be saved.

No need to fear random prions appearing from some external source when you can worry about the functional equivalent forming in your very own peptide vials:

Transmissible Proteins: Expanding the Prion Heresy - PMC

The once-heretical concept that a misfolded protein is the infectious agent responsible for prion diseases is now widely accepted. Recent exciting research has led not only to the end of the skepticism that proteins can transmit disease but also to ...

pmc.ncbi.nlm.nih.gov

I wonder if people think there's some scientific agency out there playing around with peptides the way the UGL community does, like a guardian angel, that would surely warn of the potential hazards of injecting our random concotions. And assuming, since there's no public campaign against it by the authorities, it must be safe.

Filter your peptides folks. It may not protect you completely, but it'll help reduce the risks.

 

[Dkland]

Why are you running tren?

Stats?

Height, weight, approx. BF, FFMI, years lifting, eye color, hair color, gender, fingerprints, iris scan, blood type?

Damn @readalot ………you know you’re just trying to get as accurate as you can to make a voodoo doll!!
Hahahaha

 

[readalot]

Damn @readalot ………you know you’re just trying to get as accurate as you can to make a voodoo doll!!
Hahahaha

Just trying to help our dear brother/sister/other here with some harm reduction.

 

[janoshik]

No need to fear random prions appearing from some external source when you can worry about the functional equivalent forming in your very own peptide vials:

View attachment 310646
View attachment 310651

Transmissible Proteins: Expanding the Prion Heresy - PMC

The once-heretical concept that a misfolded protein is the infectious agent responsible for prion diseases is now widely accepted. Recent exciting research has led not only to the end of the skepticism that proteins can transmit disease but also to ...

pmc.ncbi.nlm.nih.gov

I wonder if people think there's some scientific agency out there playing around with peptides the way the UGL community does, like a guardian angel, that would surely warn of the potential hazards of injecting our random concotions. And assuming, since there's no public campaign against it by the authorities, it must be safe.

Most of the peptides (in this field) are far too small to be physically capable of forming prions. The peptides(well, mostly proteins) have to be certain size to achieve 'structural flexibility' to switch like that, must have the hydrophobic areas that could subsequently be exposed and be unstable enough that interaction with 'turned brethren' would overcome the barrier to enter a different state. But not too unstable otherwise it wouldn't pass to start with.

At least that's my amateur take on it.

I just enjoy learning about these.
It's insanely interesting field of study.

 

[MissedArmDay66]

Filter your peptides folks. It may not protect you completely, but it'll help reduce the risks.

@Ghoul did you ever find any syringes with stoppers with low risk of leeching into peptides for your idea of pulling entire vial into syringe and filtering per dose?

 

[Dang-1]

OMG I have to read through more spam on TA /logistics BS. What will I do? I am so inconvenienced by this.

How bout getting the product right before ordering?

I’ve spent another 10 min QSC post scrolling for damn relevant info again to no avail. Gave up and message them for the list and sales again on WhatsApp. I do wish this thread was more useful but oh well.

 

[BamaCrazy]

I’ve spent another 10 min QSC post scrolling for damn relevant info again to no avail. Gave up and message them for the list and sales again on WhatsApp. I do wish this thread was more useful but oh well.

Could have saved yourself some time and grabbed it off Telegram. Takes like 3-4 seconds

 

[Evac513]

I’ve spent another 10 min QSC post scrolling for damn relevant info again to no avail. Gave up and message them for the list and sales again on WhatsApp. I do wish this thread was more useful but oh well.

Where else would they discuss all these other topics? It's not like there are dedicated forum sections for homebrewing, general steroid discussion, lab testing, blood work etc... oh wait actually there is.

 

[dontletheoldmanin]

Could have saved yourself some time and grabbed it off Telegram. Takes like 3-4 seconds

Where else would they discuss all these other topics? It's not like there are dedicated forum sections for homebrewing, general steroid discussion, lab testing, blood work etc... oh wait actually there is.

Just get the telegram app. Easy

 

[Evac513]

Just get the telegram app. Easy

I already have it and use it for that reason lol.

 

[Sicsemptyran]

I know I went on a lecture about how people are stupid for ignoring things they don’t want to hear that @Ghoul and @readalot bring up, but prions are pure nightmare fuel so you both are jerks for being on this forum and I’m ignoring you both. (Not really, but prions are nightmare fuel)

 

[readalot]

you both are jerks for being on this forum

I AM a jerk for being on this forum. You got me there.

I've made my piece with prions but don't use u-hCG anymore haha. Can't really say I am a fan of peptides. Maybe I am missing out. Will most likely try GH soon or stare at the $450 vial in the fridge for a while like I did with the stanozolol for a couple of years. I take my time.

 

[AnTabolic73]

Where else would they discuss all these other topics? It's not like there are dedicated forum sections for homebrewing, general steroid discussion, lab testing, blood work etc... oh wait actually there is.

But is there a prion section?!

 

[Evac513]

But is there a prion section?!

Well yeah, the QSC thread of course...

 

[UncleBuns]

I AM a jerk for being on this forum. You got me there.

I've made my piece with prions but don't use u-hCG anymore haha. Can't really say I am a fan of peptides. Maybe I am missing out. Will most likely try GH soon or stare at the $450 vial in the fridge for a while like I did with the stanozolol for a couple of years. I take my time.

I wish I could lay off the u-HCG. I've tried for many years to rid myself of obsessive thoughts about lady pee, but I always fail. I have finally found peace with my desires and come to accept who I am. If injecting lady pee quiets the demons, then so it shall be.

 

[Ghoul]

Most of the peptides (in this field) are far too small to be physically capable of forming prions. The peptides(well, mostly proteins) have to be certain size to achieve 'structural flexibility' to switch like that, must have the hydrophobic areas that could subsequently be exposed and be unstable enough that interaction with 'turned brethren' would overcome the barrier to enter a different state. But not too unstable otherwise it wouldn't pass to start with.

At least that's my amateur take on it.

I just enjoy learning about these.
It's insanely interesting field of study.

I hope my insatiable curiosity never comes off as disregarding the infinitely greater knowledge you have in this area.

As I understand it, only a subset of proteins can become infectious brain damaging prions. It requires several elements,

-----------

1. Must be able to cross the blood brain barrier.

2. They must be able to take on an amyloid configuration.

3. Have the ability to self replicate by acting as a "template" to modify existing natural cellular proteins.

----------

I'll use my favorite peptide, Semaglutide to illustrate.

GLP-1 has more research behind it. so I'll use it for reference. but the same charachteristics apply to close analogs like Sema.

----------
1. GLP-1 easily crosses the blood brain barrier.

2. GLP-1 forms amyloid fibrils as the result of simply being reconstituted in a solution with the wrong PH, unless Polysorbate 80(or similar) is included as an excipient!





"Protein or peptide aggregation into amyloid fibrils is a widespread phenomenon that plays a critical role not only in many neurodegenerative diseases but also in the stability of protein- and peptide-based biopharmaceuticals."

https://pubs.acs.org/doi/10.1021/acs.jpcb.4c01794

3. Whether GLP-1 fibrils can replicate, and what would make it happen, is unknown.

So we have 2 of the 3 factors constituting a potential prion disease present in UGL Sema, and the 3rd is an unknown.

It's been demonstrated that aggregates, including fibrils, can be significantly reduced, and their future development slowed, by filtering at .10um or larger. Unexpectedly, smaller pore sizes cause more fibrils to form.

No good can come from injecting amyloids into our bodies regardless whether they can replicate or not, especially if they can cross the blood brain barrier. So in my opinion, filtering the larger aggregates out of peptides will reduce the amount of that harmful gunk, and reduce the chances of some mutated form turning out to be something much worse years later.

 

[Black Beard]

@Qingdao Sigma Chemicals


Hey Tracy, it's been 3 weeks since my order was in customs (12/14/2024). Would i be getting a reship at 4 weeks? This sucks.


(Says "delivered to local carrier" since 12/19/2024 with zero movement)

 

[bigforyouben]

@Qingdao Sigma Chemicals


Hey Tracy, it's been 3 weeks since my order was in customs (12/14/2024). Would i be getting a reship at 4 weeks? This sucks.


(Says "delivered to local carrier" since 12/19/2024 with zero movement)

Reship is 30 days after last tracking update. If it makes you feel any better my package that was stuck since 12/19 started moving a couple days ago.

 

[The-Squat]

@Qingdao Sigma Chemicals


Hey Tracy, it's been 3 weeks since my order was in customs (12/14/2024). Would i be getting a reship at 4 weeks? This sucks.


(Says "delivered to local carrier" since 12/19/2024 with zero movement)

You have to take the holidays into consideration.