QSC - Primo 200 - Quantitative and Endotoxin test results

I'm in Canada, some of the US places 'may' ship to me.

Only $2/CAD a piece including import duties. A life time supply but a quality unit nonetheless with a "swabbable valve" so it automatically closes when the syringe is disconnected and easily sterilized with an alcohol wipe.

 
Only $2/CAD a piece including import duties. A life time supply but a quality unit nonetheless with a "swabbable valve" so it automatically closes when the syringe is disconnected and easily sterilized with an alcohol wipe.

alternately could someone not just take another needle with a filter attatched to vent?
 
Only $2/CAD a piece including import duties. A life time supply but a quality unit nonetheless with a "swabbable valve" so it automatically closes when the syringe is disconnected and easily sterilized with an alcohol wipe.

Thanks. I was looking at these too and thought it was a single unit. That’s great! These can be used on filtered finished oil vials too right? I assume the portion that goes in vial is sterile?
 
Do you mean a filtered needle to filter? Or to speed flow?
I’m relatively new to the forum and want to make sure I’m being as safe as possible with my peptides. Do you have a prior post you could maybe link me to with high level overview on how to filter to make sure what I’m injecting is safe?
 
I’m relatively new to the forum and want to make sure I’m being as safe as possible with my peptides. Do you have a prior post you could maybe link me to with high level overview on how to filter to make sure what I’m injecting is safe?
Here are some links to recent filtering discussions. There is a lot of info about why and what size, material, brands and sources where they can be purchased. Currently, the most effective type of filter for peptides is 13mm, .22um, PES Hydrophilic Membrane filters. PAY attention to "Hydrophilic" vs "Hydrophobic," because the latter will not work for peptides after reconstituting with bac water.

Peptide Filtering FDA

Finished Oils (includes filtering peptides)

Vials (includes filtering peptides)

Vials (includes filtering peptides)
 
Here are some links to recent filtering discussions. There is a lot of info about why and what size, material, brands and sources where they can be purchased. Currently, the most effective type of filter for peptides is 13mm, .22um, PES Hydrophilic Membrane filters. PAY attention to "Hydrophilic" vs "Hydrophobic," because the latter will not work for peptides after reconstituting with bac water.

Peptide Filtering FDA

Finished Oils (includes filtering peptides)

Vials (includes filtering peptides)

Vials (includes filtering peptides)

Thank you so much for all this information. What does it even mean to filter the peptides? Sorry for the dumb question, but I want to educate myself as much as possible.

Does it have to do with the reconstitution process, the injection process, or both?
 
Thank you so much for all this information. What does it even mean to filter the peptides? Sorry for the dumb question, but I want to educate myself as much as possible.

Does it have to do with the reconstitution process, the injection process, or both?
It's quite alright, these are good questions, and important for your health.

For peptides... basically, the final "compound" (after reconstituting) would be filtered. That way, what is injected has "aggregates," "bad particles," and "impurities" removed.

The main issue is removing "aggregates." These can form within the powder of the vial and/or exacerbate after reconstituting. Aggregates are basically "de-formed" or "mutated" parts of the peptide protein chains. These mutations can cause un-welcome reactions, such as an allergic response up to complete immunity against the peptide itself.

So, as an added precaution, filtering the final product prior to injection is considered a "best-practice."

Some will filter into a fresh vial. Some will filter per-injection. Of course, costs and practicality play into that.

@Ghoul
 
It's quite alright, these are good questions, and important for your health.

For peptides... basically, the final "compound" (after reconstituting) would be filtered. That way, what is injected has "aggregates," "bad particles," and "impurities" removed.

The main issue is removing "aggregates." These can form within the powder of the vial and/or exacerbate after reconstituting. Aggregates are basically "de-formed" or "mutated" parts of the peptide protein chains. These mutations can cause un-welcome reactions, such as an allergic response up to complete immunity against the peptide itself.

So, as an added precaution, filtering the final product prior to injection is considered a "best-practice."

Some will filter into a fresh vial. Some will filter per-injection. Of course, costs and practicality play into that.

@Ghoul

How would you filter per-injection? Do you pull out the entire vial's worth of reconstituted peptides into a syringe, attach filter to syringe, push solution back into the vial, then dose the insulin syringe with the daily dose?

Or is that overboard?
 
How would you filter per-injection? Do you pull out the entire vial's worth of reconstituted peptides into a syringe, attach filter to syringe, push solution back into the vial, then dose the insulin syringe with the daily dose?

Or is that overboard?

That's basically it.

Per dose had no benefit for oils, but does for peptides. Pulling the plunger out of an insulin syringe and directly backfilling is easy once you get the hang of it.

As to whether it's "overkill" depends on the peptide and your willingness to go through the extra steps. For Tesamorelin, and HGH imo, it's the way to go. But all peptides will benefit from it, or, at the least, you'll eliminate particulate contamination.

Filtering peptides once into an ultra-spec particle free vial is better than not filtering at all.

If aggregation of proteins and the threat they pose is not enough to move you, consider the other garbage in our injectables, and how much more volume we are putting directly into our bodies than even chronically ill patients,


Ready for some "fear mongering"?

"These results should be cause
for alarm."


“I never would have imagined it was this high. I certainly don’t feel comfortable with this much plastic in my brain, and I don’t need to wait around 30 more years to find out what happens if the concentrations quadruple.”
— Matthew Campen, PhD, Distinguished & Regents’ Professor, UNM College of Pharmacy
(aka ChatGPT BubbleBoy)



 
That's basically it.

Per dose had no benefit for oils, but does for peptides. Pulling the plunger out of an insulin syringe and directly backfilling is easy once you get the hang of it.

As to whether it's "overkill" depends on the peptide and your willingness to go through the extra steps. For Tesamorelin, and HGH imo, it's the way to go. But all peptides will benefit from it, or, at the least, you'll eliminate particulate contamination.

Filtering peptides once into an ultra-spec particle free vial is better than not filtering at all.

If aggregation of proteins and the threat they pose is not enough to move you, consider the other garbage in our injectables, and how much more volume we are putting directly into our bodies than even chronically ill patients,


Ready for some "fear mongering"?

"These results should be cause
for alarm."

“I never would have imagined it was this high. I certainly don’t feel comfortable with this much plastic in my brain, and I don’t need to wait around 30 more years to find out what happens if the concentrations quadruple.”
— Matthew Campen, PhD, Distinguished & Regents’ Professor, UNM College of Pharmacy (aka ChatGPT BubbleBoy)



Thanks for the quick reply!

But I'm still not following what you mean by "Pulling the plunger out of an insulin syringe and directly backfilling is easier once you get the hang of it."

Let's say I have filtered a vial of peptides into a sterile vial. If I want to filter it again before injection, do I need to re-filter the entire vial, or do you just filter the amount being injected for that day? I generally don't understand what you mean by "backfilling". (Sorry for the dumb noob questions).
 
Thanks for the quick reply!

But I'm still not following what you mean by "Pulling the plunger out of an insulin syringe and directly backfilling is easier once you get the hang of it."

Let's say I have filtered a vial of peptides into a sterile vial. If I want to filter it again before injection, do I need to re-filter the entire vial, or do you just filter the amount being injected for that day? I generally don't understand what you mean by "backfilling". (Sorry for the dumb noob questions).
I wouldn't filter peptides twice. Either once into a new vial, and use it from there, or, after reconstitution:

draw the entire vial into a 3ml syringe

remove needle

attach filter

attach needle

As you require each dose, pull the plunger out of the insulin syringe and put it on a sterile surface (I use the plunger side cap of the insulin syringe to put the rubber stopper end in and lay it down in my work surface), then, at an angle, inject the required amount of peptide, recap the filter syringe, carefully put the plunger in the syringe JUST BARELY. Flip needle side up, tap to get air to top, then push air bubble out.

Store peptide loaded filter syringe setup in refrigerator protected from light.

It sounds complex but after practice it's a 10 second process.

IMG_0436.webpIMG_0437.webpIMG_0438.webpIMG_0440.webpIMG_0435.webp
 
I wouldn't filter peptides twice. Either once into a new vial, and use it from there, or, after reconstitution:

draw the entire vial into a 3ml syringe

remove needle

attach filter

attach needle

As you require each dose, pull the plunger out of the insulin syringe and put it on a sterile surface (I use the plunger side cap of the insulin syringe to put the rubber stopper end in and lay it down in my work surface), then, at an angle, inject the required amount of peptide, recap the filter syringe, carefully put the plunger in the syringe JUST BARELY. Flip needle side up, tap to get air to top, then push air bubble out.

Store peptide loaded filter syringe setup in refrigerator protected from light.

It sounds complex but after practice it's a 10 second process.

View attachment 317480View attachment 317484View attachment 317482View attachment 317483View attachment 317476

Thank you so much! I didn't realize you store the peptide-loaded filter syringe in the refrigerator.

I assume you label the syringes in order to keep track of the peptides?

Do you swap out the filter each time you backfill an insulin syringe?
 
Thank you so much! I didn't realize you store the peptide-loaded filter syringe in the refrigerator.

I assume you label the syringes in order to keep track of the peptides?

Do you swap out the filter each time you backfill an insulin syringe?
Be extremely careful not to mix up multiple syringes by labeling ( this applies equally to vials). I use them as my early routine, and started adding color rubber bands as well in case I'm zoning it may save me from making a serious mistake.

The capacity of a 13mm syringe filter is 10ml, so while I wouldn't re-use it, I have no issue using it for the entire 3ml max of the peptide being stored in the syringe.

Use an 18 or 16 gauze needle for this. It'll minimize the risk of sheer stress damage to the peptide. A small but effortless step.
 
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