question about time it takes to lower test levels on test c.

[thejeepguy]

I have an up coming appointment. I was wondering how long it would take me to reduce testosterone levels in my blood by reducing my weekly dose of test c? Is it an instant process? In other words im taking more than im suppose to but would like to keep my prescriptions coming in. They want to keep my test at around 500 and I would like it to be around 1000-1200. I do get test C from other places but I do like having a prescription for it. I tried reading other threads but im noticing alot of back and fourth. Thank you for any assistance.

 

[readalot]

I have an up coming appointment. I was wondering how long it would take me to reduce testosterone levels in my blood by reducing my weekly dose of test c? Is it an instant process? In other words im taking more than im suppose to but would like to keep my prescriptions coming in. They want to keep my test at around 500 and I would like it to be around 1000-1200. I do get test C from other places but I do like having a prescription for it. I tried reading other threads but im noticing alot of back and fourth. Thank you for any assistance.

Apparent elimination half life of Test C about 4 to 4.5 days (mean) +/- 1.5 days (95% tile).

In 7 days your serum TT level will drop in half (conservative approach). Don't reduce your dose. Just add an extra seven days to your typical trough lab pull (for some that is skipping their weekly shot).

 

[readalot]

Should have provided reference:

For those who are struggling on TRT

I've been thinking about this thread lately. Any theories on why you seem to respond better on 1x week versus daily? I've read a number of accounts from med-high SHBG guys like you who do better on less frequent injections. I think it’s just the simple mechanism of the medication itself and...

www.excelmale.com

 

[thejeepguy]

Awesome. Thanks for the help.

 

[Sector]

Apparent elimination half life of Test C about 4 to 4.5 days (mean) +/- 1.5 days (95% tile).

In 7 days your serum TT level will drop in half (conservative approach). Don't reduce your dose. Just add an extra seven days to your typical trough lab pull (for some that is skipping their weekly shot).

about 8 days* I think the 4 to 4.5 was a typo?

 

[readalot]

about 8 days* I think the 4 to 4.5 was a typo?

See reference post above and paper therein....

The final PK parameters for total testosterone are shown in Table 2. The CL/F and V/F for tT were estimated to be 2.6 (kL/day) and 14.4 kL in healthy men with median covariate values. The median post hoc half‐life was calculated to be 4.05 days for tT.

Numbers I gave above would be IM with standard pharma 2%BA/20%BB Test cyp.

Newest subQ Xyosted (no BA / no BB) data shows apparent elimination half life up to 8 days.


Some of the early work for Test Cyp/Test Enanthate, which reported 7 days for IM, clouded by not accounting for endogenous production ...

It is difficult to calculate the PK parameters of TC using traditional noncompartmental methods, especially when the endogenous testosterone secretion rate is suppressed during the course of TC administration and the testosterone secretion rate is regulated by the LH‐testosterone feedback loop system in HPG axis. Our estimated post hoc median tT half‐life was 4.05 days, which is shorter than the mean reported elimination half‐life of 6.9 days determined using a noncompartmental analysis.11 Such inconsistency is believed to result from failure to consider endogenous testosterone production. When we assume endogenous testosterone secretion is 0 in the PPK analysis, the median estimated half‐life increases to 6.87 days.