Rebound after quitting nicotine & starting TRT. New to GLP-1s

[mmerr0314]

A little background on my situation: I am 36, 5'11". Over the last year, I managed to drop 60 lbs naturally, going from 230 down to 170. However, the rebound appetite hit me hard after I quit nicotine. To make matters trickier, I was recently prescribed TRT, which has just sort of increased my appetite even further.
I’ve gained about 20 lbs back and am currently sitting around 190.
My activity level is high—I lift 4 days a week and my job keeps me moving (10k+ steps and 20+ flights of stairs every workday). I do keep track of my macros, but the food noise and cravings for sweets get the best of me lately.
I am completely new to GLP-1s. I am looking into Tirzepatide and Retatrutide to help curb that noise so I can get back to where I was.
Could you guys help me understand the main pros and cons between Tirz and Reta for someone in my position?

 

[mmerr0314]

A little background on my situation: I am 36, 5'11". Over the last year, I managed to drop 60 lbs naturally, going from 230 down to 170. However, the rebound appetite hit me hard after I quit nicotine. To make matters trickier, I was recently prescribed TRT, which has just sort of increased my appetite even further.
I’ve gained about 20 lbs back and am currently sitting around 190.
My activity level is high—I lift 4 days a week and my job keeps me moving (10k+ steps and 20+ flights of stairs every workday). I do keep track of my macros, but the food noise and cravings for sweets get the best of me lately.
I am completely new to GLP-1s. I am looking into Tirzepatide and Retatrutide to help curb that noise so I can get back to where I was.
Could you guys help me understand the main pros and cons between Tirz and Reta for someone in my position?

Realized I forgot to mention the specific goal.
I’m looking to drop about 25 lbs to get down to around 12% body fat. The plan is to use the GLP-1 to help get me lean, and then transition into a proper cycle to focus on building muscle back on.

 

[gainslol]

This is kind of a non-answer but some people do better on Tirz and some do better on Reta so there isn't really an universal answer for this. Reta works on 3 receptors and Tirz on 2.

So in a sense Reta could be considered stronger and per weight it is, but even with that, some people respond better to Tirz.

It also depends on what side effects you experience. Reta is known to increase heart rate at least somewhat, in a decent amount of people.

Reta hasn't officially hit the market yet, if that is something that you care about.

I would read this thread, it has a lot of shared experiences:

Giant Semaglutide Thread (and other GLP-1 / GIP agonists)

Wanted to create a thread where everyone can post their experiences with different sourced Semaglutide. Who are you using? Pharma vs non? Dosage? How long have you been taking it? What are your thoughts? Have you lost weight? Side effects? Oral vs injection? Tests?

thinksteroids.com

Congrats on quitting nicotine by the way.

 

[Psy-chonaut]

*Knuckles* It's a bloody good fight within, Mate, Keep it up!

- Has the inner bitch revealed it self ? Lmao
(Let's just say that I definitely imploded a couple of times, the time when I quit)

How long have you been totally off nicotine now?

Yeah watch out, the first reward system all addicts fall into is sweets/simple sugars....

 

[mmerr0314]

*Knuckles* It's a bloody good fight within, Mate, Keep it up!

- Has the inner bitch revealed it self ? Lmao
(Let's just say that I definitely imploded a couple of times, the time when I quit)

How long have you been totally off nicotine now?

Yeah watch out, the first reward system all addicts fall into is sweets/simple sugars....

Man... So I quit smoking originally back in 2018. Then I picked up these nicotine pouches back in 2023. I officially quit around mid October and gained like 30 pounds through mid December.

The days leading up to new years I did a 72 hour fast. Which has reset my cravings for the time being.

I ordered some reta here a couple days back. I plan to just start slow on that and build up to whatever minimum dose I need.