Retatrutide + Cagrilintide

[mrvn5629]

Hello,
Does anyone here have experience with Retatrutide + Cagrilintide stacked together?
So far I’ve only been on Reta by itself. It’s been about 3–4 months since I last used Reta consistently — now I’ve only been taking it sporadically when my hunger got completely out of control. The highest dose I ever ran steadily was 6 mg weekly.
I just got my hands on both Reta and Cag and plan to start injecting tonight as extra support during my RFL diet. I’m also on 200 mg TRT per week.
Does this dosing schedule look reasonable to you?
I’m planning to start with 2 mg Retatrutide + 0.5 mg Cagrilintide and then increase every two weeks, following the progression in the picture.
Thanks...

 

[Wannabesamsulek]

You’re increasing the dose before the previous one has even had time to fully saturate. Retatrutide’s half-life is roughly a week, so it takes about 4–5 weeks per dose level to actually reach steady-state plasma levels.


Reta brings far more metabolic benefits than cagrilintide; cag is basically just an appetite suppressant. You’ll get better results by pushing reta as high as you can tolerate first and letting it handle most of the appetite control. Then bring in cag only once reta alone isn’t enough. That approach also lets you take full advantage of the added health benefits from its GIP-R and glucagon-R agonism.