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[BamaCrazy]

That's very interesting, thank you sharing that. Would love the full study to peruse.

Since some IGF-1 seemingly 'disappears' via the IM route compared to subQ, I wonder if some of it is getting converted to IGF1 - and potentially spliced to MGF - in the in injected muscle? If not the area under the curve should be the essentially same regardless of parental admin route. Higher peak with IM makes sense as absorption rate is generally IV>IM>subQ.

Overall it seems the fat loss and cognitive effects should be maximized with IM admin, while IGF1 hyperplasia/anabolic effects should be maximized with subQ admin. I've been using GH subQ for a few years now, but maybe I will trial my daytime injections IM into lagging body parts (biceps in particular), and my PM injection subQ to see if I get acheve some site enhancement via local IGF1>MGF.

When I graduated from secretagogues to GH, I would get carpal tunnel symptoms > 3 iu/day. I have now titrated up to 7iu/day (1.5iu morning + 1.5iu early evening/preworkout, and 4iu before bed) without any symptoms or water retention. I typically restrict carbs to pre- and post-workout in the pm. I do this to maximize lipolysis and minimize insulin resistance from FFA release; I also use both berberine and dihydroberberine/taxifolin with non-keto meals, and use Reta (4mg/wk taken M/W/F) and low dose empoglaflozin too. I'm probably overdoing it with insulin sensitivity drugs, but I also use rosuvastatin which increases risk of NODM - in process of switching to pitavastatin which does not.

Btw I source GH from Opti USA (40iu gold tops) and SSA (36iu). Both seem excellent. I've been using 3cc of BSW which is probably not enough, but I have been too lazy to dilute in a larger vial. I previously used K4L but had a lot of vials that mixed up cloudy, despite releasing the vacuum and gently dripping water down the sides of the vial. Still seemed to work fine but this has not been an issue with Opti or SSA.

This combo along with a low dose custom HRT protocol (testosterone, trestolone, primobolan, masteron, and trenbolone totallng 250mg/wk minus ester weight) has gotten me to (high) single digit body fat at 6' 200lbs at 57yo.

I think this is the complete study

https://www.researchgate.net/profile/Christian-Strasburger/publication/6299943_Pharmacokinetics_and_pharmacodynamics_of_GH_Dependence_on_route_and_dosage_of_administration/links/004635241e2f88c5d7000000/Pharmacokinetics-and-pharmacodynamics-of-GH-Dependence-on-route-and-dosage-of-administration.pdf

 

[Ateam2023]

I think this is the complete study

https://www.researchgate.net/profile/Christian-Strasburger/publication/6299943_Pharmacokinetics_and_pharmacodynamics_of_GH_Dependence_on_route_and_dosage_of_administration/links/004635241e2f88c5d7000000/Pharmacokinetics-and-pharmacodynamics-of-GH-Dependence-on-route-and-dosage-of-administration.pdf

Have you ever ran hgh im @BamaCrazy ?

 

[BamaCrazy]

Have you ever ran hgh im @BamaCrazy ?

No. But this topic has gotten me curious. Mainly about whether the sides associated with GH are better or worse going IM. I’ve had to tap out with GH and now Tesa due to weeks long awful carpal tunnel. I’ve lowered doses, stayed hydrated, kept up on electrolytes and taurine, but nothing helps.

 

[bigforyouben]

No. But this topic has gotten me curious. Mainly about whether the sides associated with GH are better or worse going IM. I’ve had to tap out with GH and now Tesa due to weeks long awful carpal tunnel. I’ve lowered doses, stayed hydrated, kept up on electrolytes and taurine, but nothing helps.

Might be actual carpal tunnel. I stopped the GH and kept the CTS, and a nerve study confirmed it. I just got release surgery a few days ago.

 

[BamaCrazy]

Might be actual carpal tunnel. I stopped the GH and kept the CTS, and a nerve study confirmed it. I just got release surgery a few days ago.

When I was getting out of the Army they diagnosed me with mild carpal tunnel. But I had no constant symptoms at the time. A month after getting up to 4iu a day I started having symptoms which went away once I stopped GH. 4 months into Tesa I started having symptoms again. It’s only been 1 week since I stopped Tesa so I’m hoping the symptoms go away this time also.

 

[Ateam2023]

When I was getting out of the Army they diagnosed me with mild carpal tunnel. But I had no constant symptoms at the time. A month after getting up to 4iu a day I started having symptoms which went away once I stopped GH. 4 months into Tesa I started having symptoms again. It’s only been 1 week since I stopped Tesa so I’m hoping the symptoms go away this time also.

you could get that nerve test , to determine if you actually have ct, if that's something you can do or are willing to do,?

 

[BamaCrazy]

you could get that nerve test , to determine if you actually have ct, if that's something you can do or are willing to do,?

That’s how they diagnosed me with mild CT. They connected wires to me and shocked the crap out of me. lol. That was back in 2017.

 

[Photon]

No. But this topic has gotten me curious. Mainly about whether the sides associated with GH are better or worse going IM. I’ve had to tap out with GH and now Tesa due to weeks long awful carpal tunnel. I’ve lowered doses, stayed hydrated, kept up on electrolytes and taurine, but nothing helps.

Sides will probably be worse going IM with the higher peak.
Peaks usually causes more sides, which is why sometimes we seek out stable levels.

I'm just trying to figure out which gives more fat loss, since the GH AUC is much higher, it seems to indicate a potential for higher fat loss at the cost of IGF.

 

[Photon]

What is the shelf life here in general and specific ATP.

Lol this looks interesting.
Someone should buy this in a few months and get this tested.

The sodium salt is water soluble, routinely yielding a clear solution at 50 mg/ml. This solution is mildlyacidic (pH approximately 3.5). Neutral ATP solutions stored frozen are stable for at least one year. Arefrigerated solution would be stable for at least one week (see special concerns regarding standards forbioluminescence).

https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/774/126/a6144pis.pdf?msockid=1689e7bf654a6ffd2195f1a664476e0c

 

[CharlesV]

But this topic has gotten me curious.

same here. definitely interested in learning more about IM vs SQ.

 

[songsofpyramids]

Mainly about whether the sides associated with GH are better or worse going IM.

IM greatly reduces side effects for me. I’d get tingly fingers and numb hands until I switched to IM and they disappeared. I find the “feel” of IM is nicer in general for me personally.

 

[Rippidy Dippidy]

Last weeks DXA work? And yes, I rounded down .5. Oh well. Shoot me.

Let’s see a pic tho. My Dexa scan seemed to be off by a couple percentages and I use to think it was the gold standard. But then I seen a YouTube video recently of Brian Shaw taking one at 360lbs + if I’m not wrong saying he’s 15% body fat, which is complete and utter bullshit.
Made me think I wasted every penny even getting mine checked after I seen that video.

Last weeks DXA work? And yes, I rounded down .5. Oh well. Shoot me.

 

[Jeffholio5]

IM greatly reduces side effects for me. I’d get tingly fingers and numb hands until I switched to IM and they disappeared. I find the “feel” of IM is nicer in general for me personally.

On days where I feel puffy or tingly in my hands/elbows I’ll pop am hctz and that seems to help sort it out for me but that’s all anecdotal

 

[BamaCrazy]

On days where I feel puffy or tingly in my hands/elbows I’ll pop am hctz and that seems to help sort it out for me but that’s all anecdotal

How much are you taking? I tested this out today with 50mg and I feel like it helped with the swelling and tingling in my hands.

 

[Trailmixed]

No. But this topic has gotten me curious. Mainly about whether the sides associated with GH are better or worse going IM. I’ve had to tap out with GH and now Tesa due to weeks long awful carpal tunnel. I’ve lowered doses, stayed hydrated, kept up on electrolytes and taurine, but nothing helps.

What dose of Tesa were you running?

 

[BamaCrazy]

What dose of Tesa were you running?

2mg a day. I made it to the 4 month mark before I started getting CT symptoms.

 

[Trailmixed]

2mg a day. I made it to the 4 month mark before I started getting CT symptoms.

Yeah, I havent ran it yet, mostly because when I ride a bike or something else with holding a bar for a prolonged time, I start getting CTS symptoms in the median nerve distribution.

I've heard from some anecdotally that if you run 0.5-1mg it keeps those neg sides off like CTS/noticeable water retention.

 

[Jeffholio5]

How much are you taking? I tested this out today with 50mg and I feel like it helped with the swelling and tingling in my hands.

Usually 25mg but I could see 50mg being helpful too bc 25mg doesn’t always fully relieve that feeling. Just have to watch electrolytes on hctz which is why I only use it as needed and not daily.

 

[CarvinDC125]

Close, but no cigar.
You get 0.936%

BA density is close to water, but not the same (1.04g/ml vs 1g/ml)

For 30ml of 0.9% BAC you need:

0.26 mL Benzyl Alcohol
29.74 mL sterile water

Is it that damn serious? Do I really need to measure 29.74 ml of water? Would adding 30 units of BA to 30ml of water really be too strong?

 

[CarvinDC125]

What dose of Tesa were you running?

So are people talking about trying HGH IM or Tesamorelin IM?
The later ran IM definitely feels better pip wise. But I only ran it six months then switched to actual HGH because I heard you don’t get as good benefits from Tesamorelin once your in your 40s
I did get a six pack on Tesa though. It 100% burns the hell out of visceral fat.
Regular HGH has a better effect overall though. HGH made my upper body real pronounced and bubbly. Like polishes everything up kinda. Tesa didn’t do that, it just gave me a six pack but maybe I just didn’t do it long enough