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[dcfreak]

I personally believe so. I posted about it quite a few pages back here, and speculated as much due to my wife and my experience switching from another reputable sources GH we'd been on for months, to SSA's 36iu GH. We both experienced more frequent urination, and my daily water intake shot up significantly. It's not enough to make me not want to buy SSA GH any more, but that's just because of how good a value it is. If price was equal, it wouldn't even be a question. For what it's worth, I've bought several more kits of SSA's GH since noticing this, and don't plan to stop.


Edit: found the post I made
View attachment 342243

Interesting. I also run SSA gh currently and have been thirsty AF and have to pee more at night. I have heard that they possibly add mannitol.

 

[Ghoul]

Interesting. I also run SSA gh currently and have been thirsty AF and have to pee more at night. I have heard that they possibly add mannitol.

Virtually all UGL GH uses mannitol as an excipient. Pharma does as well.

Thats how the "diuretic in rHGH" stuff started.

You need at least 20g injected for a diuretic effect, not the .01g in an average dose of rHGH.

 

[Ghoul]

You guys better check your fasting glucose.

You may be mistaking GH induced pre-diabetes for diuretics.

Every pharma GH box has a pamphlet with this:



Consider getting on Reta or Tirz to get your insulin sensitivity back and stopping this.

On the bright side, like carpel tunnel and aching joints, if this is happening you know it's legit and working!

 

[dcfreak]

You guys better check your fasting glucose.

You may be mistaking GH induced pre-diabetes for diuretics.

Every pharma GH box has a pamphlet with this:

View attachment 342245

Consider getting on Reta or Tirz to get your insulin sensitivity back and stopping this.

On the bright side, like carpel tunnel and aching joints, if this is happening you know it's legit and working!

I have been on reta for 26 or so weeks. Fasting glucose was 77 this morning.

For me the thirst is actually welcome. Took months to look at water and food the same due to the retatrutide.

I will definitely keep an eye on the glucose. Thank you!

 

[Ghoul]

I have been on reta for 26 or so weeks. Fasting glucose was 77 this morning.

For me the thirst is actually welcome. Took months to look at water and food the same due to the retatrutide.

I will definitely keep an eye on the glucose. Thank you!

To be honest I've experience the increased thirst and need to urinate as well (always in the middle of outdoor cardio, lol). I have a CGM and noticed those sides follow a few minutes after a glucose spike.

 

[Alvinq]

Virtually all UGL GH uses mannitol as an excipient. Pharma does as well.

Thats how the "diuretic in rHGH" stuff started.

You need at least 20g injected for a diuretic effect, not the .01g in an average dose of rHGH.

I don't doubt what you're saying but the effects for me were literally the next morning after my first GH pin and every day since. I've been pissing like I'm 80 since that day. Can't even make it through a workout without stopping to pee.
I have blood work that included fasting glucose and fasting insulin currently being processed so waiting on the results.
Also currently on Tirzepatide.

 

[Ghoul]

I don't doubt what you're saying but the effects for me were literally the next morning after my first GH pin and every day since. I've been pissing like I'm 80 since that day. Can't even make it through a workout without stopping to pee.
I have blood work that included fasting glucose and fasting insulin currently being processed so waiting on the results.
Also currently on Tirzepatide.

Honestly, there's not going to be a diuretic in the GH. That's been a rumor for decades, before testing was available, and now that testing is common it's never been found.

It's like the carpal=contaminants thing. This is just what GH does. Some will be more sensitive than others. GH changes sodium retention balance and boosts eGFR (kidney filtration rate). Then it gets converted to IGF which stimulates local water retention around connective tissue (causing carpal).

So water distribution in the body can get all out of whack.

It often balances out after a month or so.

 

[AllGoodThings]

Virtually all UGL GH uses mannitol as an excipient. Pharma does as well.

Thats how the "diuretic in rHGH" stuff started.

You need at least 20g injected for a diuretic effect, not the .01g in an average dose of rHGH.

You guys better check your fasting glucose.

You may be mistaking GH induced pre-diabetes for diuretics.

Every pharma GH box has a pamphlet with this:

View attachment 342245

Consider getting on Reta or Tirz to get your insulin sensitivity back and stopping this.

On the bright side, like carpel tunnel and aching joints, if this is happening you know it's legit and working!

I switched back to the other GH and the thirst and frequent urination went away very quickly. Switched back again, and it's back. I wasn't expecting any of this, so I highly doubt it's psychosomatic. Any other possible explanations? I've been on Retatrutide at 3mg/week throughout all of this.

 

[Alvinq]

I switched back to the other GH and the thirst and frequent urination went away very quickly. Switched back again, and it's back. I wasn't expecting any of this, so I highly doubt it's psychosomatic. Any other possible explanations? I've been on Retatrutide at 3mg/week throughout all of this.

Fix us @Ghoul. Make us stop pissing!

 

[niqTM]

I tested mine in late July. 480 igf1 levels on 3iu gh per night and 6mg reta in a once weekly injection.

Holy. Mine is only 285 from 4iu. What am I doing wrong?

 

[verylargeshoes]

Fix us @Ghoul. Make us stop pissing!

DHT will take care of that for you, given time.

 

[IndividualMan]

DHT will take care of that for you, given time.

Prostatemaxxing so i never have to piss again

 

[Ghoul]

I switched back to the other GH and the thirst and frequent urination went away very quickly. Switched back again, and it's back. I wasn't expecting any of this, so I highly doubt it's psychosomatic. Any other possible explanations? I've been on Retatrutide at 3mg/week throughout all of this.

I don't think it's psychosomatic either.

I think if you're using the same dose with each. one is more bioactive than the other, and I bet head to head IGF after two weeks on each would prove this.

Most people don't know what IU really means. It's not a weight. It's a measure of rHGH activity.

The "standard" is 3iu per mg of rHGH.

Pharma takes a mg of their rHGH, puts it in a vial with specially grown cells that have HGH receptors. Then they measure how much IGF is produced to get "iu of bioactivity".

It has to be between 2.6iu and 3.1iu to meet FDA standard. As long as it's between these two numbers they are allowed to call it 3iu/mg on the box.

These days modern production is so good they sometimes get above 3.1iu/mg, and have to dilute it to lower bioactivity.

The reason it varies is that while rHGH can be 99% pure on HPLC, there are many types of rHGH "defects" that can't. be detected in purity tests, and the only true measure of how well it will attach to receptors is with a bioactivity test.

Unlike pharma, UGL rHGH doesn't get thrown out if it's out of bioactivity range. it's not even checked. It could be 2.1iu/mg or 4iu/mg. It all gets called 3iu/mg.

So now you know. Two batches of UGL rHGH, same purity, same dose, can have significantly different levels of bioactivity.

The one that's more bioactive will cause more rHGH effects, both desirable, and sides.

 

[dasking]

Another happy interaction with SSA, received the items I was missing in a pack. No arguing or fighting with them. I will still always record opening packs. I can fully understand people trying to take advantage of them, but its refreshing to not have any drama. Proof provided or not ive had vendors be far less professional, SSA did me right and was kind and professional.

 

[TTren]

You guys better check your fasting glucose.

You may be mistaking GH induced pre-diabetes for diuretics.

Every pharma GH box has a pamphlet with this:

View attachment 342245

Consider getting on Reta or Tirz to get your insulin sensitivity back and stopping this.

On the bright side, like carpel tunnel and aching joints, if this is happening you know it's legit and working!

will metformin help with this

 

[niqTM]

Another happy interaction with SSA, received the items I was missing in a pack. No arguing or fighting with them. I will still always record opening packs. I can fully understand people trying to take advantage of them, but its refreshing to not have any drama. Proof provided or not ive had vendors be far less professional, SSA did me right and was kind and professional.

who was your rep?

 

[Ghoul]

will metformin help with this

850mg x 2 day negated the increased insulin resistance of (approx) 5-6iu rHGH.

Effects of a combination of recombinant human growth hormone with metformin on glucose metabolism and body composition in patients with metabolic syndrome - PubMed

Abdominal obesity and insulin resistance are central findings in metabolic syndrome. Since treatment with recombinant human growth hormone (rhGH) can reduce body fat mass in patients with organic GH deficiency, rhGH therapy may also have favourable effects on patients with metabolic syndrome...

pubmed.ncbi.nlm.nih.gov

 

[krvuxn]

You guys better check your fasting glucose.

You may be mistaking GH induced pre-diabetes for diuretics.

Every pharma GH box has a pamphlet with this:

View attachment 342245

Consider getting on Reta or Tirz to get your insulin sensitivity back and stopping this.

On the bright side, like carpel tunnel and aching joints, if this is happening you know it's legit and working!

I’d definitely recommend the cardio route before “prescribing” someone a GLP. But maybe I’m old fashioned. 10 minute walks after eating.

 

[Photon]

Another happy interaction with SSA, received the items I was missing in a pack. No arguing or fighting with them. I will still always record opening packs. I can fully understand people trying to take advantage of them, but its refreshing to not have any drama. Proof provided or not ive had vendors be far less professional, SSA did me right and was kind and professional.

The warehouse staff take pictures when packing your pack. They know what's missing or not.

 

[Spaceman Spiff]

I don't think it's psychosomatic either.

I think if you're using the same dose with each. one is more bioactive than the other, and I bet head to head IGF after two weeks on each would prove this.

Most people don't know what IU really means. It's not a weight. It's a measure of rHGH activity.

The "standard" is 3iu per mg of rHGH.

Pharma takes a mg of their rHGH, puts it in a vial with specially grown cells that have HGH receptors. Then they measure how much IGF is produced to get "iu of bioactivity".

It has to be between 2.6iu and 3.1iu to meet FDA standard. As long as it's between these two numbers they are allowed to call it 3iu/mg on the box.

These days modern production is so good they sometimes get above 3.1iu/mg, and have to dilute it to lower bioactivity.

The reason it varies is that while rHGH can be 99% pure on HPLC, there are many types of rHGH "defects" that can't. be detected in purity tests, and the only true measure of how well it will attach to receptors is with a bioactivity test.

Unlike pharma, UGL rHGH doesn't get thrown out if it's out of bioactivity range. it's not even checked. It could be 2.1iu/mg or 4iu/mg. It all gets called 3iu/mg.

So now you know. Two batches of UGL rHGH, same purity, same dose, can have significantly different levels of bioactivity.

The one that's more bioactive will cause more rHGH effects, both desirable, and sides.

I agree dude. Let's do some NMR testing like you kept talking about.


I don't know if you noticed the 10+ tags, you didn't seem to respond

Post in thread 'MESO "Specialized" Testing Group Fund'

Jul 10, 2025

I'll match @Ghoul up to $50. I don't use GH, but I like the idea of this.

ill throw down 100+ 5x(up to 50)of whatever @Ghoul donates for the dumb fucking NMR test

So just 100 dollars from me


The trailer park boys are here to get nasty

• Spaceman Spiff

• 
• 

Seriously. Im glad people started taking you with a grain of salt of how much talk you do with little to no real action lololol