Simple Epo guidelines

[Vladovic]

- Take baby aspirin (75-100mg) once daily

- Don't use SERMs at the same time as EPO

- Stay hydrated

- Do not use if hematocrit level exceeds 52%.

- Do not use if serum ferritin level is below 20. Pre load iron 2-3weeks prior Epo cycle. Ferrochel is a good oral iron, 12 ferrochels a day in 3-4 divided doses with oral VitC works fine. Or iron injection per week (i.e ferlixit)

- Monitor hematocrit at least once a week.

- How long do pre-filled syringes last? Up to expiry date in the fridge (4ºC) although potency can fall before this point.

- Recommended cycle? Once weekly subcutaneous dosing. See Heuberger 2017 study.

 

[Millard]

Heuberger, J. A. A. C., Rotmans, J. I., Gal, P., Stuurman, F. E., van ’t Westende, J., Post, T. E., Daniels, J. M. A., Moerland, M., van Veldhoven, P. L. J., de Kam, M. L., Ram, H., de Hon, O., Posthuma, J. J., Burggraaf, J., & Cohen, A. F. (2017). Effects of erythropoietin on cycling performance of well trained cyclists: A double-blind, randomised, placebo-controlled trial. The Lancet Haematology, 4(8), e374–e386. Redirecting

8-week EPO dosing schedule: