Study regarding hcg usage for 14+ days

[fizzisnumerouno]

Kind of interesting study if you ask me.
The effects of chronic human chorionic - PubMed Mobile

 

[Michael Scally MD]

Kind of interesting study if you ask me.
The effects of chronic human chorionic - PubMed Mobile

What is interesting?

Risbridger GP, Robertson DM, de Kretser DM. The effects of chronic human chorionic gonadotropin treatment on Leydig cell function. Endocrinology 1982;110(1):138-45. http://press.endocrine.org/doi/abs/10.1210/endo-110-1-138

The purpose of this study was to examine the effect of chronic daily hCG treatment on interstitial cell function in the rat, as judged by plasma testosterone levels, the testicular binding of labeled hCG, and the capacity of the testis to respond to gonadotropin stimulation by the production of testosterone in vitro.

Twenty-four hours after the first injection of 100 IU hCG there was a significant decline in hCG binding to testis homogenates and an inability to respond to hCG stimulation in vitro. After 7 days of daily injections of 10 IU or 100 IU hCG, the loss of hCG binding was maintained. However, despite the marked decline in hCG binding, there was an enhanced testosterone response to hCG stimulation in vitro, and plasma testosterone levels were significantly elevated.

With continued injections of hCG for 14 or 21 days, the testes remained hyperresponsive to hCG stimulation in vitro, but hCG binding returned to control levels, and plasma testosterone concentrations declined and were not statistically different from controls. The latter changes probably result from the formation of specific hCG antibodies (Kd at 4 C, 7.8 +/- 4.5 X 10(-10) M) that were detected in plasma from rats treated for 14 or mopre days with hCG.

The formation and levels of the hCG antibodies in these animals were sufficient to neutralize the effects of the exogenous hCG, thereby returning plasma testosterone levels to normal and restoring the complement of hCG receptors.

 

[Michael Scally MD]

As the OP has been banned, there is no expectation for an answer. There would have been no answer had he not been banned since he was clueless regarding hCG. Also, he posted the same study on another thread that contradicts his OP.

Regardless, the rat study means NOTHING for clinical use. Moreover, the abstract states, "plasma testosterone levels were significantly elevated." So it is any guess where this was going. Possibly another vain ignorant uninformed attempt at Leydig Cell Desensitization, which is a myth.

 

[CensoredBoardsSuck]

As the OP has been banned, there is no expectation for an answer. There would have been no answer had he not been banned since he was clueless regarding hCG. Also, he posted the same study on another thread that contradicts his OP.

Regardless, the rat study means NOTHING for clinical use. Moreover, the abstract states, "plasma testosterone levels were significantly elevated." So it is any guess where this was going. Possibly another vain ignorant uninformed attempt at Leydig Cell Desensitization, which is a myth.

I bet no one ever experienced Leydig Cell Desensitization from HCDeGenerate. [)]

 

[illuminatty]

Hcdegenerate lolol!!