Switching from tirz to reta

[Nflz63]

Hi everyone,

I’m currently on 5mg tirzepatide and thinking about switching to retatrutide. For those who’ve done it:

• Did you use a washout or switch directly?
• What starting dose worked best?
• Any noticeable differences in side effects or fat loss?

Thanks!

 

[Civdiv]

I switched directly from 5mg tirz to 4mg reta. For the transition I pinned 2mg, then 3 days later another 2. After that I was back pinning once a week at 4mg. 1st 2 weeks I got pretty hungry as the tirz ramped down and reta ramped up. By the start of the 3rd week I was questioning whether I needed to drop the reta dose. Been 4 weeks now and doing great. Still at 4mg a week.

 

[Nflz63]

Does reta suppress appetite as much as tirz ?

 

[Civdiv]

I don't feel as much suppression at this dose but it goes back and forth. There's some meals where I'm starving and could eat double what I'm eating, and later in the day I have to force feed to hit my calories. On tirz I never really felt hungry at all. If I wasn't about to up my calories in a couple weeks I'd probably up my reta dose. I hear of some people getting massive suppression at only 2mg Reta so I think it's kind of individual how it works for you.