Synthesizing chemicals from scratch

[substratums]

I've seen these videos from Chinese biotech sellers showing how they make their generic HGH.

Watch pxVIjeukaHHFFH5fw1t_305758745386_mp4_264_sd | Streamable

Watch "pxVIjeukaHHFFH5fw1t_305758745386_mp4_264_sd" on Streamable.

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Watch 2azmhQjCZk22hkuZpHk_305401456371_mp4_264_ld | Streamable

Watch "2azmhQjCZk22hkuZpHk_305401456371_mp4_264_ld" on Streamable.

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Where would you start in learning how to do this? What equipment would be required for someone to do it at a much smaller scale, straight from their home without a facility (if that's even possible)?

 

[janoshik]

I've seen these videos from Chinese biotech sellers showing how they make their generic HGH.

Watch pxVIjeukaHHFFH5fw1t_305758745386_mp4_264_sd | Streamable

Watch "pxVIjeukaHHFFH5fw1t_305758745386_mp4_264_sd" on Streamable.

streamable.com

Watch 2azmhQjCZk22hkuZpHk_305401456371_mp4_264_ld | Streamable

Watch "2azmhQjCZk22hkuZpHk_305401456371_mp4_264_ld" on Streamable.

streamable.com

Where would you start in learning how to do this? What equipment would be required for someone to do it at a much smaller scale, straight from their home without a facility (if that's even possible)?

View attachment 147547

That's not the actual manufacturing process in either of those videos.

That's just sealing the vials, which is very well doable manually (equipment cost of about 25$ for the manual way ) - quite not elegant, though, and dispensing dissolved GH and fillers into the vials themselves via peristaltic pump ( which you can get for a few hundred $ ).

 

[Ridethelightningbarefoot]

Well first you need a heard of ecoli. Then you gotta feed the ecoli to keep em alive but every now and then inject them with a virus to make them produce gh. You have milk the ecoli tits to make sure you get all of it out with a old milk pale of course....see where this is going? You just gotta start a ecoli farm

 

[TrennedOutLunatic]

That's not the actual manufacturing process in either of those videos.

That's just sealing the vials, which is very well doable manually (equipment cost of about 25$ for the manual way ) - quite not elegant, though, and dispensing dissolved GH and fillers into the vials themselves via peristaltic pump ( which you can get for a few hundred $ ).

Spot on.
No synthesis in these videos.

 

[TrennedOutLunatic]

Well first you need a heard of ecoli. Then you gotta feed the ecoli to keep em alive but every now and then inject them with a virus to make them produce gh. You have milk the ecoli tits to make sure you get all of it out with a old milk pale of course....see where this is going? You just gotta start a ecoli farm

In layman's terms...yeah,that's pretty much it.

 

[BarbellBaby1]

Take it from a chemist--you are not going to be synthesizing these raws in your apartment. You can encapsulate raw powders, create suspensions, etc. but you are not synthesizing these compounds from scratch without a well-stocked synth lab.

 

[TRT]

Take it from a chemist--you are not going to be synthesizing these raws in your apartment. You can encapsulate raw powders, create suspensions, etc. but you are not synthesizing these compounds from scratch without a well-stocked synth lab.

What would these well stocked labs have exactly?

 

[klokke23]

Equipment you won't be able to get. Unless you have connections with Madrigal electric motors

 

[BarbellBaby1]

What would these well stocked labs have exactly?

Bare minimum:

A well-stocked lab would need to have multiple precursor molecules (or raws souced from a different) lab and a method to purify their compounds. Either flash chromatography coupled with NMR to confirm compound purity or running that batch through HPLC-HRMS (4 decimal places req'd) to confirm purity that way. I'd also want them to have some sort of vacuum oven or other proprietary way of drying down the compounds to eliminate residual solvent from synthesis.

I have zero experience on the encapsulation side of chem but have extensive experience on the synthesis side of things lol. While I'm fairly new to exploring AAS's, it seems like the majority of these guys aren't actually the synthesis labs themselves & that they're sourcing raws from Latvia/China (Latvia, weirdly enough, is an absolute hot bed of synth labs).

It's going to be hard to be an underground *synthesis* lab as the sheer capital needed to get contracts for the proper instrumentation for chromatography and analysis, let alone the glassware needed to run these experiments (distillation setups frequently get seized by customs) leads me to assume most are merely importing raws and encapsulating them in-house.

Not a bad gig but slightly misleading imo lol

 

[janoshik]

A well-stocked lab would need to have multiple precursor molecules (or raws souced from a different) lab and a method to purify their compounds. Either flash chromatography coupled with NMR to confirm compound purity or running that batch through HPLC-HRMS (4 decimal places req'd) to confirm purity that way.

Somehow I feel like I can tell you are an academic and not from the industry.

The approach you suggest is way too expensive and very inappropriate for routine QA/QC. The setup you suggest is more suited for experimental work. Definitely not necessary for routine tests of products from well defined processes at industrial scale.

Most Chinese use 20 year old LC-UVs you could get off ebay for like 500$ as their QA/QC. And frankly, it would be sufficient if they knew how to use those.

 

[MFAAS]

I've seen these videos from Chinese biotech sellers showing how they make their generic HGH.

Watch pxVIjeukaHHFFH5fw1t_305758745386_mp4_264_sd | Streamable

Watch "pxVIjeukaHHFFH5fw1t_305758745386_mp4_264_sd" on Streamable.

streamable.com

Watch 2azmhQjCZk22hkuZpHk_305401456371_mp4_264_ld | Streamable

Watch "2azmhQjCZk22hkuZpHk_305401456371_mp4_264_ld" on Streamable.

streamable.com

Where would you start in learning how to do this? What equipment would be required for someone to do it at a much smaller scale, straight from their home without a facility (if that's even possible)?

View attachment 147547

I would say just don't even try. If you don't have a chemistry degree and serious experience in a lab, then you should not be trying to synthesize anything from scratch, you are more likely to do yourself serious harm.

So, if you want to do this, go back to school, take a bunch of advanced chemistry classes, then you can think about it more lol.

 

[FR0Z3N_B0MB3RRR]

You need a Van first... and to grow mustache...

Then, as suggested, you have to buy escherichia coli and feed them, they like iso whey at most, tell them that you wanna have some Serostim or Humatrope... show them some pics, pay them well monthly, give them the iso whey they like and for sure they ll give you those really cool HGH pens... escherichia coli are very hard and realiable workers if you know how to deal with them..

I bought some billions of them on Amazon, very satisfied

 

[TRT]

Bare minimum:

A well-stocked lab would need to have multiple precursor molecules (or raws souced from a different) lab and a method to purify their compounds. Either flash chromatography coupled with NMR to confirm compound purity or running that batch through HPLC-HRMS (4 decimal places req'd) to confirm purity that way. I'd also want them to have some sort of vacuum oven or other proprietary way of drying down the compounds to eliminate residual solvent from synthesis.

I have zero experience on the encapsulation side of chem but have extensive experience on the synthesis side of things lol. While I'm fairly new to exploring AAS's, it seems like the majority of these guys aren't actually the synthesis labs themselves & that they're sourcing raws from Latvia/China (Latvia, weirdly enough, is an absolute hot bed of synth labs).

It's going to be hard to be an underground *synthesis* lab as the sheer capital needed to get contracts for the proper instrumentation for chromatography and analysis, let alone the glassware needed to run these experiments (distillation setups frequently get seized by customs) leads me to assume most are merely importing raws and encapsulating them in-house.

Not a bad gig but slightly misleading imo lol

It's funny cause I remember a point in time when everyone said the same thing before home brewing before it became the norm.

 

[TRT]

Somehow I feel like I can tell you are an academic and not from the industry.

The approach you suggest is way too expensive and very inappropriate for routine QA/QC. The setup you suggest is more suited for experimental work. Definitely not necessary for routine tests of products from well defined processes at industrial scale.

Most Chinese use 20 year old LC-UVs you could get off ebay for like 500$ as their QA/QC. And frankly, it would be sufficient if they knew how to use those.

I knew I wouldn't understand anything he said but at the same time I was sure it would drag someone out who would. So I guess my next question is...is this doable? Can we come up with an at home process?

 

[FR0Z3N_B0MB3RRR]

Homebrewing is fuckin stupid... like making a fuckin tea... HGH making requires living bacteria which they somehow injected a retrovirus to change their dna expression to make them synthesize Human Growth Hormone... than you have to extract it and purify it without damaging it and a protein like HGH isnt like Testosterone...

And then to make it into vials...


homebrewing isnt synthesizing steroids...

If youre have to ask it here if its doable , the answer is clearly Laughing at you.. if you have to ask it here you have no clue at all about anything related..

Do you wanna make HGH at home to resell it?

Yes man, very doable... send me 4k $ in bitcoin i ll tell you HOW TO... step by step

i ll send a wallet address via PM... go champ.. you ll be Anke Bio little brother... thousand$$$$

start wondering what supercar you should buy...

i suggest you to start with a McLaren 765LT

 

[TrennedOutLunatic]

It's funny cause I remember a point in time when everyone said the same thing before home brewing before it became the norm.

And I am just doing it here in my bathtub Hahhahahhahahahhahaahahahah

 

[TRT]

And I am just doing it here in my bathtub Hahhahahhahahahhahaahahahah

That's the best kind. "Bath gains".

 

[FR0Z3N_B0MB3RRR]

@TrennedOutLunatic youre the hero your city deserves ... BATH MAN

 

[BarbellBaby1]

Somehow I feel like I can tell you are an academic and not from the industry.

The approach you suggest is way too expensive and very inappropriate for routine QA/QC. The setup you suggest is more suited for experimental work. Definitely not necessary for routine tests of products from well defined processes at industrial scale.

Most Chinese use 20 year old LC-UVs you could get off ebay for like 500$ as their QA/QC. And frankly, it would be sufficient if they knew how to use those.

Yeah, I'm defnitely in academia lol but we've had some industries send samples to our analytical chemists for QA/QC and I haven't heard of anyone still using UV for this. LC-MS, yes, but not LC-UV. It might just be the type of samples we run which clients prefer HPLC-HRMS but man I haven't heard of UV being used outside our biochem depts lol

 

[janoshik]

Yeah, I'm defnitely in academia lol but we've had some industries send samples to our analytical chemists for QA/QC and I haven't heard of anyone still using UV for this. LC-MS, yes, but not LC-UV. It might just be the type of samples we run which clients prefer HPLC-HRMS but man I haven't heard of UV being used outside our biochem depts lol

LC-UV is literally the most used technique in the industry by far and for a good reason

MS sucks in every conceivable way for most routine process QA/QC. Way more expensive, more downtime, more maintenance, more personnel needed, less accurate, less precise, needs more sample prep, etc etc. Great for research, great for trace work, terrible for most other stuff.

We are talking well defined manufacturing processes where you are looking at the same peaks all day every day (all research already done) on your multi kilo batches (thus no trace work either).