don't listen to the non sense people posting here
take it 1x a day or 3x a day, it's split up to reduce side effects of thyroid storm
t3 can be taken with or without food, but certain minerals and other medications can affect absorption, ie iron, calcium, anti acids, so food with iron/calcium should be avoided, i think the recommendation is to not take iron/calcium 4 hours within dose of t3, as it is usually completely absorbed in 4 hours
people are described up to 75mcg, considering you're going to be suppressing your thyroid completely 50-75mcg is what you'd most likely use
that being said, you should do bloodwork to check if your free t3 levels go out of range, if it does, you should lower the dosage a bit and keep it in the upper normal