OmL
Member
Just here to learn, my first AI was aromasin and it suits me well so I’ve never had to be tire elsewhere.They both bind in the same way, it's just that arimidex only binds temporarily but exemstane binds forever. To prevent a rebound from arimidex, you don't need ever increasing doses. Instead, a regularly administered dose is needed so any newly freed aromatase can be occupied by the circulating arimidex. For the record, I've never had any kind of rebound type thing on adex.
