Tirzepatide reconstitution last

[AJJones85]

tirzepatide when reconstituted and put in fridge does it still only last for 4 weeks? Or could you get longer out of it.

Thanks

 

[Nidus]

"Tirz will survive a nuclear war" - @Sampei

 

[Sampei]

tirzepatide when reconstituted and put in fridge does it still only last for 4 weeks? Or could you get longer out of it.

Thanks

90+ days easily

 

[AJJones85]

90+ days easily

Thanks @Sampei

 

[Ghoul]

Thanks @Sampei

No one can answer this question without testing that goes beyond what Jano does,

These claims are based on a flawed testing methodology that doesn't measure the loss of stability, backed up by "feels" that "prove" if it has any effect, it's "fine".

What's the PH? The wrong PH speeds up degradation 10x. Many other factors are also involved, and every vial of UGL differs.

Even professional researchers occasionally make this mistake. I recently read a study that measured degeneration the way Jano did in the studies used to claim Tirzapatide is impervious. When they corrected the error, purity went from approx 95% to 65%.

The main problem is that in order to analyze the compound, it has to be filtered with a .22um syringe filter first, removing most impurities,

What you can be sure of is that by reconstituting with 3ml, you'll slow degeneration. By filtering you'll eliminate bacteria and a large proportion of the aggregates that speed up degradation, and reduce the risk from those contaminants.

 

[AJJones85]

No one can answer this question without testing that goes beyond what Jano does,

These claims are based on a flawed testing methodology that doesn't measure the loss of stability, backed up by "feels" that "prove" if it has any effect, it's "fine".

What's the PH? The wrong PH speeds up degradation 10x. Many other factors are also involved, and every vial of UGL differs.

Even professional researchers occasionally make this mistake. I recently read a study that measured degeneration the way Jano did in the studies used to claim Tirzapatide is impervious. When they corrected the error, purity went from approx 95% to 65%.

The main problem is that in order to analyze the compound, it has to be filtered with a .22um syringe filter first, removing most impurities,

What you can be sure of is that by reconstituting with 3ml, you'll slow degeneration. By filtering you'll eliminate bacteria and a large proportion of the aggregates that speed up degradation, and reduce the risk from those contaminants.

Am not gonna lie I had to read this 4 times to what you’re saying.
Am guessing this’ll be the same for all peptide?

 

[Ghoul]

Am not gonna lie I had to read this 4 times to what you’re saying.
Am guessing this’ll be the same for all peptide?

Every peptide differs in stability. Some are durable, some are fragile, the formulation (other ingredients) makes a big difference, and most of the time we have no idea what those ingredients are in UGL peptides.

But there are certain factors that apply to them all. I've had the same peptide from two different labs, same dose, reconstituted within a day of each other. One lost activity within a month, the other still worked a year later when I unexpectedly found it.

Keeping them more dilute slows aggregation (peptide molecules sticking together to form inactive clumps that reduce the amount of the drug).

Keeping them cold slows degeneration.

Avoiding agitation, bubbles, and foam slows degeneration.

Light speed up degeneration.

The presence of bacteria speeds up degeneration.

Aggregation can happen almost instantly, or take a long time to form, and the clock starts once reconstituted, so within reason, smaller dosed vials that can be used more quickly are preferable. For instance, I've noticed the price of 30mg Tirz vials are often the same per mg as 60mg, making them a better choice.

 

[Sampei]

Am not gonna lie I had to read this 4 times to what you’re saying.
Am guessing this’ll be the same for all peptide?

I'll make you a TLDR of it.

He doesn't have any data to prove his point, I have Jano Labtest showing loss of purity -0.xx% after 90 days, loss of quantity -0.xx mg after 90 days.

One thing he said correctly not all peptides are the same, Tirzepatide is super resistant.dont assume all other will behave the same.

Do with it whatever you want

 

[AJJones85]

Every peptide differs in stability. Some are durable, some are fragile, but there are certain factors that apply to them all.

Keeping them more dilute slows aggregation (peptide molecules sticking together to form inactive clumps that reduce the amount of the drug).

Keeping them cold slows degeneration.

Avoiding agitation, bubbles, and foam slows degeneration.

Light speed up degeneration.

The presence of bacteria speeds up degeneration.

Aggregation can happen almost instantly, or take a long time to form, and the clock starts once reconstituted, so within reason, smaller dosed vials that can be used more quickly are preferable.

thanks for the information
Make sense to get the smaller doses, I got 20mg tirzepatide she’s still on the 2.5 week and has been since December so won’t get no bigger then 20mg for now.