Toxicity of benzyl alcohol and benzyl benzoate

[filtros29]

So far I've been using the common method of sterilizing vials, but it occurred to me to put them once crimped inside the autoclave, I think that could be the final step to ensure sterilization, I mean, one more barrier to have a totally safe vial, plus I have some gear from outside that I would like to go through this step.
So, what happens chemically with benzyl alcohol and benzyl benzoate when they reach 138º Celsius? According to the internet, both compounds can decompose and produce toxic gases such as carbon monoxide and dioxide, but that is only if something external makes them ignite, which does not happen inside the autoclave.
Also, does anyone know if it is harmful for the hormone to reach these temperatures for 30 minutes?
If anyone has information I would greatly appreciate it.

 

[SunWukong]

@Ghoul

 

[Ghoul]

It's fine.

This is an FDA compliant compounding pharmacy recipe for Test-cyp.


Look at the final sterilization in step 5.

https://www.medisca.net/pdf/shortage-support/en-us/injection/F%20004%20571v2%20Testosterone%20100%20mg%20per%20mL%20Intramuscular%20Injection.pdf

 

[filtros29]

Wow! thank you so much for the valuable information, you have saved my day, this question was keeping me up at night.
By the way, and this is a separate topic, I don't know if I should open another thread, do you guys know anything about why Test E is cloudy? Last night I made 200ml, it had a perfect color, totally transparent with a slight yellowish tone, today when I got up after letting it mix, I see that it is cloudy, I have used the standard recipe, 1% BA and 15% BB

 

[filtros29]

Something curious about this is that I put the oil over 60º Celsius to better dissolve the mixture, last time I dissolved it at room temperature, does this have something to do with it? I should do the test. Another thing that bothers me is that the last time I prepared vials the last two vials came out cloudy, there were 20 in total, if they were from the same bottle, why the hell did the last ones come out cloudy?

 

[Alibabaa]

Wow! thank you so much for the valuable information, you have saved my day, this question was keeping me up at night.
By the way, and this is a separate topic, I don't know if I should open another thread, do you guys know anything about why Test E is cloudy? Last night I made 200ml, it had a perfect color, totally transparent with a slight yellowish tone, today when I got up after letting it mix, I see that it is cloudy, I have used the standard recipe, 1% BA and 15% BB

Either the raw material still had too much moisture or it came into contact with the solution during brewing (some use warm water to heat the glass container). Simply heat it again long enough and the moisture will escape. What is important, however, is that it is heated in an open container.

 

[filtros29]

Either the raw material still had too much moisture or it came into contact with the solution during brewing (some use warm water to heat the glass container). Simply heat it again long enough and the moisture will escape. What is important, however, is that it is heated in an open container.

Hello, thanks for the reply, I just tried it and it becomes cloudy again when it returns to 20º Celsius, I'm intrigued, because, if it's not due to an emulsion (due to humidity inside the vial) or a lack of filtering, I tried refiltering it, nor is it due to a lack of solvents, I already tried increasing the benzyl benzoate to 25%, then what could it be due to?