I am in a state of confusion right now, I belong to another board and people tell me I need to run an anti-prolactin with Tren, though I have read elsewhere that this is a myth. My other question is would Dextroamphetamine have an anti-prolactin effect since it raises dopamine levels (this would be convenient since I have it and not an anti-prolactin). Also I am running Test and Tren, 3 weeks on and 3 off, would an anti-prolactin even be warranted with such a short cycle, if it is even necessary at all.
MESO-Rx
Anabolic Steroids
Trenbolone, Anti-Prolactin, & Dextroamphetamine
- Thread starter TheGuy85
- Start date
beezil
New Member
i have run many tren cycles and never needed to run an antiprolactin.
maybe if running (2) nor19's. however, i would not recommend that.
lastly, if running 3 weekers or short cycles. be sure to use short esters Prop and Acetate.
beezil
New Member
rotate the following and you won't have to worry about quads...
delts, chest, bis, and glutes.... repeat.
try a 27g x .5in
Can I swap bis with tris? Delts are spoiling me to be honest, fucking 10x easier than poking myself in the ass? All I got are 25g x 1in atm, It goes all the way in my delt, I really didn't intend to put it in that far it just kind of happened today while I was trying to pin my right delt with my left hand.
beezil
New Member
i used to use 25g x 1in exclusively. so no worries there.
you can pin wherever you want bro... its your body. try it you just might like it!
I'm telling you what works for me. By no means is it gospel....
good luck.
you can pin wherever you want bro... its your body. try it you just might like it!
I'm telling you what works for me. By no means is it gospel....
good luck.
weekend
New Member
amphetamine will temporarily lower prolactin but after a tolerance is built you will see no decrease in prolactin because dopamine will not stay elevated forever.
amphetamine is not a dopamine agonist but a dopamine reuptake inhibitor and releaser. it does not lead to sustained higher dopamine activity, and there will always be a rebound when ceasing use (lower dopamine and higher prolactin)
long story short: use a dopamine agonist. amphetamine is also hard on the heart and stresses the body, worsening the mental and physical effects of tren.
amphetamine is not a dopamine agonist but a dopamine reuptake inhibitor and releaser. it does not lead to sustained higher dopamine activity, and there will always be a rebound when ceasing use (lower dopamine and higher prolactin)
long story short: use a dopamine agonist. amphetamine is also hard on the heart and stresses the body, worsening the mental and physical effects of tren.
The first problem is you're getting information from other boards. Why would you do that?
Second, without a legitimate medical need for d-amphetamine, its use is pointless because you're trying to treat something that doesn't exist, i.e., trenbolone induced hyperprolactinemia.
Regardless, here are a couple of papers looking at the effect of d-amphetamine on PRL.
Horm Metab Res. 1983 Sep;15(9):439-43.
Prolactin lowering effect of amphetamine in normoprolactinemic subjects and in physiological and pathological hyperprolactinemia. Prolactin lowering effect of amphetamine in n... [Horm Metab Res. 1983] - PubMed - NCBI
DeLeo V, Cella SG, Camanni F, Genazzani AR, Müller EE.
Abstract
The effect on plasma prolactin (PRL) of d-amphetamine (Amph) was studied in normo- and hyperprolactinemic subjects. In normoprolactinemic women Amph failed to lower plasma PRL levels when infused intravenously over 1 h at the dose of 7.5 mg, but induced at the dose of 15.0 mg a modest inhibition of plasma PRL (maximum PRL inhibition 20 +/- 4.5% at 45 min). Likewise, in puerperal women Amph at the dose of 7.5 mg did not decrease significantly plasma PRL levels but it was active in this respect (maximum inhibition 37 +/- 10% at 120 min) at the dose of 15.0 mg. In subjects with presumptive evidence of a PRL-secreting adenoma, Amph at either the 7.5 mg or the 15.0 mg dose failed to alter baseline PRL levels. These results indicate that Amph is a poor PRL suppressor in either normo- or hyperprolactinemic subjects. It is proposed that this may be due to the drug's ability to effect release of dopamine mainly from a non-granular pool of the amine.
Gynecol Obstet Invest. 1987;23(2):103-9.
Prolactin changes after administration of agonist and antagonist dopaminergic drugs in puerperal women. Prolactin changes after administration... [Gynecol Obstet Invest. 1987] - PubMed - NCBI
Petraglia F, De Leo V, Sardelli S, Mazzullo G, Gioffrè WR, Genazzani AR, D'Antona N.
Abstract
Prolactin (PRL) is an anterior pituitary hormone which plays a large part in the reproductive function of mammals. Its only well-documented effect in humans is that of initiating and maintaining lactation. Among hypothalamic neurotransmitters regulating the anterior pituitary function, dopamine (DA) is currently considered to correspond to the PRL-inhibiting factor. The central control mechanisms which induce high PRL levels in puerperal women are not well understood. To study DA tonus in puerperium we tested plasma PRL levels in different groups of puerperal subjects (6 per group) after acute administration of direct or indirect DA agonists or placebo: DA, L-dopa (a DA precursor), L-dopa plus carbidopa (a peripheral dopa-decarboxylase inhibitor), nomifensine (a DA-releasing and blocking or reuptake agent) and amphetamine (a DA releaser). The same tests with the same drug doses were performed on groups of healthy volunteers. A consistent reduction in plasma PRL levels after both direct and indirect DA agonist drugs compared to placebo was evident in puerperal and in control women. A different trend was only observed with the use of DA and amphetamine in puerperal subjects, who, unlike controls, failed to show a rebound in plasma PRL levels after the termination of drug infusion. These findings support the view that the inhibitory control of tuberoinfundibular neurons over PRL secretion is maintained in puerperium and changes in the affinity of DA receptors are related to the endocrine milieu which occurs during gestation.
I already get prescribed D-Amph (just started taking it for it prescribed purposes) and was wondering about the Trenbolone increasing prolactin thing, which came up on another board, and didn't know if adderall affected prolactin levels. I was already under the impression that the prolactin increase with trenbolone was a myth (had no evidence to support it) but I am not knowledgeable about such things. Good post, I tried looking stuff up but couldn't find anything on search engine related to d-amphetamine and prolactin levels, but you found a nice study it seems.
