Ultra sensitive LC/MS estradiol vs standard?

marsupial

Member
How exactly is the standard test erroneous? From what I’ve seen it typically overestimates E2 by a factor of 2 or so, but has it ever underestimated it and just been totally randomly wrong? Honestly if we are aware that it multiplies the “real” E2 by 1.5-2, I think we can still use it in conjunction with any symptoms to figure out whether E2 is crashed, low, or high?

Not only does ultrasensitive cost more, but it seems to take far more time (10d) to come back, whereas standard comes back the next day. 10d is a lot of days of a blast to waste sitting on your hands, but if standard E2 levels are so highly unreliable in either direction, there may not be much of a choice if you want to minimize risk of crashing E2
 
My Ultrasensitive test has never taken longer than the rest of my bloodwork (2-3 business days for everything)

I’m not sure where you get it from but the important thing for me is not getting a range or a calculation. I want to know the number, period. This helps me balance my dosages with things like EQ or primo. I believe I’ve seen that other compounds (especially tren) can throw off your estrogen numbers if it’s not an ultrasensitive test.
And lastly, having to multiple by 1.5-2 can be the difference between a 75 and 100 result. That’s a decent gap to move between.

Honestly it probably doesn’t matter for casual users. If you’re just running some TRT and anavar and aren’t having side effects, a general range should suffice. But I’d say it’s important to get ultrasensitive every once in a while just so you can track exact numbers.
 
L
My Ultrasensitive test has never taken longer than the rest of my bloodwork (2-3 business days for everything)

I’m not sure where you get it from but the important thing for me is not getting a range or a calculation. I want to know the number, period. This helps me balance my dosages with things like EQ or primo. I believe I’ve seen that other compounds (especially tren) can throw off your estrogen numbers if it’s not an ultrasensitive test.
And lastly, having to multiple by 1.5-2 can be the difference between a 75 and 100 result. That’s a decent gap to move between.

Honestly it probably doesn’t matter for casual users. If you’re just running some TRT and anavar and aren’t having side effects, a general range should suffice. But I’d say it’s important to get ultrasensitive every once in a while just so you can track exact numbers.
I understand the margin of error can be big at certain magnitudes, but for me who is running test and primo, prefers E not to be too high, and just wants to ensure it’s not crashed, about to crash, or too low (that it’d be a health concern re lack of cardio/neuroprotectivity longterm), standard should suffice right? Have you in fact seen the standard vary in the lower direction compared to ultra sensitive? Eg, I just got std e2 3d ago and it came back at <15 pg. Currently taking 200 test 100 primo and took a bit too much AI (6.25 mg ed on first day and then 12.5 mg for 3d leading to blood draw due to night sweats, which in hindsight were probably due to general hormone change rather than e2 rising). I have no symptoms at all of low estrogen other than being a bit tired and sleeping for about 9h a night, but I discontinued asin when the e2 came back.

Why was I aggressive with e2 control? Because on my first blast with test alone with AI e3d, I had higher e2 and it fucked with my sleep, gave me acne, and made me irritable and impulsive.

Also where do you get your ultra sensitive that it takes 2-3d. PrivateMD takes roughly 10 for the ultrasensitive E2 alone. I presume that wouldn’t change even if I ordered in conjunction with a fuller panel?

Just trying to decide how to draw e2 the next time so I can do it asap to see how to increase the test/primo dosing, but also want to prevent crashing e2.
 
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I honestly don’t understand how young kids are getting into this stuff without proper research. Even after you do all the research (much of which will only make sense when you start your first cycle), there’s a fine line between not being neurotic and making informed decisions about cycle design. Really makes you think that most people on gear are fucking themselves up rather than improving their lives
 
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