Boldenone (EQ) Misconceptions and Comparison with Metenolone (Primo) [Author: Type-IIx]

[asaly]

Maybe I wrote not perfectly, Schanzer called Boldenone differently than you (I) the name of the compound you gave refers to the compound (VIII) and according to pubchem it is called boldione

 

[readalot]

Maybe I wrote not perfectly, Schanzer called Boldenone differently than you (I) the name of the compound you gave refers to the compound (VIII) and according to pubchem it is called boldione

Boldione is the dione form of boldenone (prohormone)...

Characterization of boldione and its metabolites in human urine by liquid chromatography/electrospray ionization mass spectrometry and gas chromatography/mass spectrometry - PubMed

Boldione (1,4-androstadiene-3,17-dione) is a direct precursor (prohormone) to the anabolic steroid boldenone (1,4-androstadiene-17beta-ol-3-one). It is advertised as a highly anabolic/androgenic compound promoting muscularity, enhancing strength and overall physical performance, and is available...

pubmed.ncbi.nlm.nih.gov

Boldione, that is simply the dione form of boldenone, is activated in the body by the same widely distributed 17b-hydroxysteroid dehydrogenase enzyme that converts androstendione into testosterone

Schematic...

https://ars.els-cdn.com/content/image/1-s2.0-S0960852419304079-ga1.jpg

17β-carbonyl reduction is the term you want to understand here.

https://www.sciencedirect.com/science/article/abs/pii/S0960852419304079

Efficient One-Step Biocatalytic Multienzyme Cascade Strategy for Direct Conversion of Phytosterol to C-17-Hydroxylated Steroids - PMC

Steroidal 17-carbonyl reduction is crucial to the production of natural bioactive steroid medicines, and boldenone (BD) is one of the important C-17-hydroxylated steroids. Although efforts have been made to produce BD through biotransformation, the ...

www.ncbi.nlm.nih.gov

Fig. 1

Figure - PMC

Steroidal 17-carbonyl reduction is crucial to the production of natural bioactive steroid medicines, and boldenone (BD) is one of the important C-17-hydroxylated steroids. Although efforts have been made to produce BD through biotransformation, the ...

www.ncbi.nlm.nih.gov

Carbonyl reduction - Wikipedia

en.wikipedia.org

17β-Hydroxysteroid dehydrogenase - Wikipedia

en.m.wikipedia.org

 

[asaly]

I'll read the whole thing tomorrow but with what you posted it also defies words

Boldenone is 1,4-androstadiene-3,17-dione

The essence of the problem is that I look critically at the thesis that boldione aromatization is 100% the same as boldenone aromatization

 

[Type-IIx]

@Type-IIx

(shaking head)

 

[Type-IIx]

@asaly oh yeah I just basically wasn't reading anything you said based on past encounters. This is boldione which is like AD to T. The aromatization is the same for both, not affected by the 17β-OH.

 

[asaly]

@asaly oh yeah I just basically wasn't reading anything you said based on past encounters. This is boldione which is like AD to T. The aromatization is the same for both, not affected by the 17β-OH.

Couldn't you have written at the beginning that you think 17beta OH doesn't affect aromatization but instead insert several posts about how smart you are compared to me?

I have now read that AD aromatizes indeed as effectively as T, but can we be 100% sure that there is such an analogy for EQ/boldione?

 

[lukiss96]

I think something happened to @Type-IIx, he's usually a kind person, unless you intentionally step on his feet. Perhaps just a bad day at the office or something.

That's all I got to say, I will leave science talk to you both now gentlemen, I have not much to offer in terms of knowledge on this quite complex subject you talk about.

 

[readalot]

I have now read that AD aromatizes indeed as effectively as T, but can we be 100% sure that there is such an analogy for EQ/boldione?

Look at the structure of boldione vs. boldenone. What is the difference?

How does that compare to AD and T? Looking at the functional groups should help with the understanding.

What are their direct products of aromatization (building off the AD and T analogy)?

 

[readalot]

Couldn't you have written at the beginning that you think 17beta OH doesn't affect aromatization but instead insert several posts about how smart you are compared to me?

I have now read that AD aromatizes indeed as effectively as T, but can we be 100% sure that there is such an analogy for EQ/boldione?

Once you complete the exercise above you'll understand the statement below is false as written (bold on the boldenone is mine). Boldenone does not directly aromatize to estrone.

Reality: Boldenone aromatizes (to estrone [E1] & estradiol

Reality: Boldione aromatizes (to estrone [E1] & estradiol [E2]

The E1 to E2 is of course back to the 17β-carbonyl reduction step shared up above.

 

[asaly]

@readalot
you are explaining things I understand, my doubt was about those numbers, why we used % conversion of test and boldione for calculations

I hadn't noticed before that in this table AD has the same %conversion as test, which actually explains to me why the value for boldione was used, but I still don't know if we can be 100% convinced that equal values of AD and T will translate into equal values of EQ and boldione

 

[Mongo966]

I think something happened to @Type-IIx, he's usually a kind person, unless you intentionally step on his feet. Perhaps just a bad day at the office or something.

That's all I got to say, I will leave science talk to you both now gentlemen, I have not much to offer in terms of knowledge on this quite complex subject you talk about.

We think his account might have been hacked by Janoshik.

 

[asaly]

I think something happened to @Type-IIx, he's usually a kind person, unless you intentionally step on his feet. Perhaps just a bad day at the office or something.

he is kind of nervous towards me, I didn't write anything wrong just politely asked why he used boldione values for boldenone calculations

And he made up that I was stalking him all over the forum to ridicule him, when I kept saying that I was just a fan of his knowledge and enjoyed reading him

 

[readalot]

If we can be 100% convinced that equal values of AD and T will translate into equal values of EQ and boldione

Assumption based on boldione and EQ having exact same androgen backbone (look at the A ring) and AD vs T results. Of course the primary products of aromatization will be different (boldione --> estrone vs boldenone --> estradiol).

 

[buzzingonaas]

I am confused by some of the wording. Is this saying that the trial was ran with EQ and primo at below minimal effective anabolic dose? And that is where it was found to be less toxic than primo? Or are those two separate clinical trials?

 

[readalot]

I don't really know how to equip you to understand this besides instructing you to take Chem courses at a community college.

You need some uni level chem bro. I'm not trying to humiliate you I'm trying to explain to you that there's a knowledge barrier that is limited by your education.

Boldenone is 1,4-androstadiene-3,17-dione which aromatizes at an absolute rate of 35%, yielding the aromatic products estrone and estradiol.

 

[Type-IIx]

We think his account might have been hacked by Janoshik.

I saw Jano's thread, he was downloading a lot of pent up rage on Millard, but it was just misdirected. He probably feels his livelihood is at stake and/or that he's been treated unfairly while stakes are high.

I feel that way when I am (was?) prepping to invest a lot into selling my book too. I think it's best to just focus on my business for now.

 

[Mongo966]

I saw Jano's thread, he was downloading a lot of pent up rage on Millard, but it was just misdirected. He probably feels his livelihood is at stake and/or that he's been treated unfairly while stakes are high.

I feel that way when I am (was?) prepping to invest a lot into selling my book too. I think it's best to just focus on my business for now.

Yeah I think we all know it's probably just the stress of the book getting to you a bit.
Maybe it's time for a vacation once the book comes out.

 

[Fattyone]

I think something happened to @Type-IIx, he's usually a kind person, unless you intentionally step on his feet. Perhaps just a bad day at the office or something.

That's all I got to say, I will leave science talk to you both now gentlemen, I have not much to offer in terms of knowledge on this quite complex subject you talk about.

Seems things went south when people started showing up and pointing out flaws In his big word replies. He lost his shit and started calling names and acting childish when people were challenging him.

I used to read (or try to at least) his posts and took them at gospel. After this last week though I don’t view them, or him the same.

 

[AlexDavis43]

This thread turned out to be not very shitty. Kudos, gentlemen.

The verdict: get your fucking blood work done regularly and try to keep track of all the gear you've been taking. Make a chart or something.

 

[TTren]

I just got done running EQ for the first time in years. I wanted to give it another chance to see if perhaps I would like it better or get better results from it running it longer. If I had it to do again I’d have ran something else for the blast.

Eq gives me some vascularity that looks good. No real bad sides otherwise. No real anything otherwise.

I retain my opinion from before. It’s a waste of syringe space.

it lowers e2 its u dont even need an ai when running it I was on 1200mg test with 400eq no gyno while on 600mg tren